HUMAN:THTPA

Species (Taxon ID)	Homo sapiens (Human). (9606)
Gene Name(s)	THTPA
Protein Name(s)	Thiamine-triphosphatase ThTPase
External Links
UniProt	Q9BU02
EMBL	AF432862 AK057691 BX161435 BX378775 AL135999 CH471078 CH471078 BC002984
CCDS	CCDS32053.1 CCDS58307.1
RefSeq	NP_001119811.1 NP_001242991.1 NP_001243250.1 NP_001243251.1 NP_001243252.1 NP_077304.1
UniGene	Hs.655179 Hs.732304 Hs.736905
PDB	3BHD 3TVL
PDBsum	3BHD 3TVL
ProteinModelPortal	Q9BU02
SMR	Q9BU02
BioGrid	122595
IntAct	Q9BU02
STRING	9606.ENSP00000288014
PhosphoSite	Q9BU02
DMDM	37538018
MaxQB	Q9BU02
PaxDb	Q9BU02
PeptideAtlas	Q9BU02
PRIDE	Q9BU02
DNASU	79178
Ensembl	ENST00000288014 ENST00000404535 ENST00000554789 ENST00000556015
GeneID	79178
KEGG	hsa:79178
UCSC	uc001wkg.5 uc031qnv.1
CTD	79178
GeneCards	GC14P024025
HGNC	HGNC:18987
HPA	HPA028876
MIM	611612
neXtProt	NX_Q9BU02
PharmGKB	PA38774
eggNOG	NOG42323
GeneTree	ENSGT00390000005996
HOGENOM	HOG000154571
HOVERGEN	HBG057173
InParanoid	Q9BU02
KO	K05307
OMA	RDTYYDT
OrthoDB	EOG7288SN
PhylomeDB	Q9BU02
TreeFam	TF333398
BRENDA	3.6.1.28
Reactome	REACT_11117
ChiTaRS	THTPA
EvolutionaryTrace	Q9BU02
GenomeRNAi	79178
NextBio	68161
PRO	PR:Q9BU02
Proteomes	UP000005640
Bgee	Q9BU02
CleanEx	HS_THTPA
ExpressionAtlas	Q9BU02
Genevestigator	Q9BU02
GO	GO:0005829 GO:0016787 GO:0000287 GO:0050333 GO:0016311 GO:0006091 GO:0044281 GO:0042357 GO:0006772 GO:0042723 GO:0006766 GO:0006767
Gene3D	2.40.320.10
InterPro	IPR023577 IPR012177
Pfam	PF01928
PIRSF	PIRSF036561
SUPFAM	SSF55154
PROSITE	PS51707

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
	GO:0005515		PMID:21049048	ECO:0000021		UniProtKB:P35372			Figure 2 and 3 both show ThTpase activity with the protein	complete
enables	GO:0050333	thiamin-triphosphatase activity	PMID:11827967	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
involved_in	GO:0042357	thiamine diphosphate metabolic process	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q8JZL3	P		Seeded From UniProt	complete
involved_in	GO:0016311	dephosphorylation	PMID:11827967	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0006091	generation of precursor metabolites and energy	PMID:11827967	ECO:0000303	author statement without traceable support used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0000287	magnesium ion binding	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q8JZL3	F		Seeded From UniProt	complete
enables	GO:0050333	thiamin-triphosphatase activity		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:2446078 PANTHER:PTN001026440 UniProtKB:Q9BU02	F		Seeded From UniProt	complete
involved_in	GO:0042357	thiamine diphosphate metabolic process		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:2446078 PANTHER:PTN001026440	P		Seeded From UniProt	complete
involved_in	GO:0016311	dephosphorylation		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN001026440 UniProtKB:Q9BU02	P		Seeded From UniProt	complete
enables	GO:0000287	magnesium ion binding		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:2446078 PANTHER:PTN001026440	F		Seeded From UniProt	complete
enables	GO:0050333	thiamin-triphosphatase activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q8JZL3 ensembl:ENSMUSP00000056026	F		Seeded From UniProt	complete
involved_in	GO:0042357	thiamine diphosphate metabolic process	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q8JZL3 ensembl:ENSMUSP00000056026	P		Seeded From UniProt	complete
enables	GO:0000287	magnesium ion binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q8JZL3 ensembl:ENSMUSP00000056026	F		Seeded From UniProt	complete
involved_in	GO:0006772	thiamine metabolic process	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR012177	P		Seeded From UniProt	complete
enables	GO:0050333	thiamin-triphosphatase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR012177 InterPro:IPR039582	F		Seeded From UniProt	complete
enables	GO:0050333	thiamin-triphosphatase activity	GO_REF:0000003	ECO:0000501	evidence used in automatic assertion	EC:3.6.1.28	F		Seeded From UniProt	complete
enables	GO:0016787	hydrolase activity	PMID:11827967	ECO:0000304	author statement supported by traceable reference used in manual assertion		F		Seeded From UniProt	complete
involved_in	GO:0006772	thiamine metabolic process	PMID:11827967	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0042723	thiamine-containing compound metabolic process	Reactome:R-HSA-196819	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0005829	cytosol	Reactome:R-HSA-965067	ECO:0000304	author statement supported by traceable reference used in manual assertion		C		Seeded From UniProt	complete
enables	GO:0046872	metal ion binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0479	F		Seeded From UniProt	complete
enables	GO:0016787	hydrolase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0378	F		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0963 UniProtKB-SubCell:SL-0086	C		Seeded From UniProt	complete
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References

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