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HUMAN:SSBP

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Species (Taxon ID) Homo sapiens (Human). (9606)
Gene Name(s) SSBP1 (synonyms: SSBP)
Protein Name(s) Single-stranded DNA-binding protein, mitochondrial

Mt-SSB MtSSB PWP1-interacting protein 17

External Links
UniProt Q04837
EMBL M94556
AF277319
BC000895
CCDS CCDS5866.1
PIR JN0568
RefSeq NP_001243439.1
NP_001243440.1
NP_001243441.1
NP_001243442.1
NP_003134.1
UniGene Hs.490394
PDB 1S3O
2DUD
3ULL
PDBsum 1S3O
2DUD
3ULL
ProteinModelPortal Q04837
SMR Q04837
BioGrid 112620
IntAct Q04837
MINT MINT-3025472
STRING 9606.ENSP00000265304
PhosphoSite Q04837
UCD-2DPAGE Q04837
MaxQB Q04837
PaxDb Q04837
PeptideAtlas Q04837
PRIDE Q04837
DNASU 6742
Ensembl ENST00000265304
ENST00000465582
ENST00000481508
ENST00000484178
ENST00000498107
ENST00000570667
ENST00000571430
ENST00000574199
ENST00000575059
ENST00000576834
ENST00000612337
GeneID 6742
KEGG hsa:6742
UCSC uc003vwo.2
CTD 6742
GeneCards GC07P141445
HGNC HGNC:11317
HPA HPA002866
MIM 600439
neXtProt NX_Q04837
PharmGKB PA36141
eggNOG COG0629
GeneTree ENSGT00390000002796
HOVERGEN HBG001181
InParanoid Q04837
KO K03111
OMA ITYGEIT
PhylomeDB Q04837
TreeFam TF314629
Reactome REACT_200608
ChiTaRS SSBP1
EvolutionaryTrace Q04837
GeneWiki SSBP1
GenomeRNAi 6742
NextBio 26300
PRO PR:Q04837
Proteomes UP000005640
UP000005640
Bgee Q04837
CleanEx HS_SSBP1
ExpressionAtlas Q04837
Genevestigator Q04837
GO GO:0070062
GO:0042645
GO:0005739
GO:0005634
GO:0003682
GO:0044822
GO:0003697
GO:0006260
GO:0070584
GO:0051096
Gene3D 2.40.50.140
HAMAP MF_00984
InterPro IPR012340
IPR000424
IPR011344
PANTHER PTHR10302
Pfam PF00436
PIRSF PIRSF002070
SUPFAM SSF50249
TIGRFAMs TIGR00621
PROSITE PS50935

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

part_of

GO:0070062

extracellular exosome

PMID:20458337[1]

ECO:0007005

high throughput direct assay evidence used in manual assertion

C

part_of:(CL:0000639)

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

PMID:21630459[2]

ECO:0007005

high throughput direct assay evidence used in manual assertion

C

part_of:(CL:0000019)

Seeded From UniProt

complete

part_of

GO:0042645

mitochondrial nucleoid

PMID:18063578[3]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0051096

positive regulation of helicase activity

PMID:12975372[4]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0003723

RNA binding

PMID:22681889[5]

ECO:0007005

high throughput direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0003723

RNA binding

PMID:22658674[6]

ECO:0007005

high throughput direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0003682

chromatin binding

PMID:18063578[3]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0051096

positive regulation of helicase activity

PMID:21873635[7]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000033807
UniProtKB:Q04837

P

Seeded From UniProt

complete

part_of

GO:0042645

mitochondrial nucleoid

PMID:21873635[7]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000033809
SGD:S000007222
UniProtKB:Q04837

C

Seeded From UniProt

complete

involved_in

GO:0006264

mitochondrial DNA replication

PMID:21873635[7]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0010438
PANTHER:PTN000033809

P

Seeded From UniProt

complete

part_of

GO:0005739

mitochondrion

PMID:21873635[7]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0010438
MGI:MGI:1920040
PANTHER:PTN000033809
SGD:S000007222
TAIR:locus:2015353
UniProtKB:Q04837
UniProtKB:Q8GWJ4

C

Seeded From UniProt

complete

enables

GO:0003697

single-stranded DNA binding

PMID:21873635[7]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG10976
FB:FBgn0010438
PANTHER:PTN000033807
PomBase:SPAC2F3.04c
SGD:S000007222
TAIR:locus:2015353
UniProtKB:P9WGD5
UniProtKB:Q8I415

F

Seeded From UniProt

complete

part_of

GO:0005739

mitochondrion

GO_REF:0000052

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0070584

mitochondrion morphogenesis

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9CYR0
ensembl:ENSMUSP00000031971

P

Seeded From UniProt

complete

part_of

GO:0005739

mitochondrion

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9CYR0
ensembl:ENSMUSP00000031971

C

Seeded From UniProt

complete

enables

GO:0003697

single-stranded DNA binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000424
InterPro:IPR011344

F

Seeded From UniProt

complete

involved_in

GO:0006260

DNA replication

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR011344

P

Seeded From UniProt

complete

involved_in

GO:0007005

mitochondrion organization

Reactome:R-HSA-1592230

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005759

mitochondrial matrix

Reactome:R-HSA-1592241

ECO:0000304

author statement supported by traceable reference used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0006260

DNA replication

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0235

P

Seeded From UniProt

complete

part_of

GO:0005739

mitochondrion

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0496
UniProtKB-SubCell:SL-0173

C

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0238

F

Seeded From UniProt

complete

part_of

GO:0042645

mitochondrial nucleoid

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-1135
UniProtKB-SubCell:SL-0269

C

Seeded From UniProt

complete

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Notes

References

See Help:References for how to manage references in GONUTS.

  1. ↑ Buschow, SI et al. () MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis. Immunol. Cell Biol. 88 851-6 PubMed GONUTS page
  2. ↑ de Mateo, S et al. (2011) Proteomic characterization of the human sperm nucleus. Proteomics 11 2714-26 PubMed GONUTS page
  3. ↑ 3.0 3.1 Bogenhagen, DF et al. (2008) The layered structure of human mitochondrial DNA nucleoids. J. Biol. Chem. 283 3665-75 PubMed GONUTS page
  4. ↑ Korhonen, JA et al. (2003) TWINKLE Has 5' -> 3' DNA helicase activity and is specifically stimulated by mitochondrial single-stranded DNA-binding protein. J. Biol. Chem. 278 48627-32 PubMed GONUTS page
  5. ↑ Baltz, AG et al. (2012) The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts. Mol. Cell 46 674-90 PubMed GONUTS page
  6. ↑ Castello, A et al. (2012) Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. Cell 149 1393-406 PubMed GONUTS page
  7. ↑ 7.0 7.1 7.2 7.3 7.4 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
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