GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.

Have any questions? Please email us at ecoliwiki@gmail.com

HUMAN:SMC2

From GONUTS
Jump to: navigation, search
Species (Taxon ID) Homo sapiens (Human). (9606)
Gene Name(s) SMC2 (synonyms: CAPE, SMC2L1)
Protein Name(s) Structural maintenance of chromosomes protein 2

SMC protein 2 SMC-2 Chromosome-associated protein E hCAP-E XCAP-E homolog

External Links
UniProt O95347
EMBL AF092563
AL833191
AL161791
AL354938
AL354938
AL161791
CH471105
BC130385
AF113673
BN000163
CCDS CCDS35086.1
RefSeq NP_001036015.1
NP_001036016.1
NP_001252531.1
NP_006435.2
XP_006716996.1
UniGene Hs.119023
ProteinModelPortal O95347
SMR O95347
BioGrid 115841
DIP DIP-35422N
IntAct O95347
MINT MINT-1161754
STRING 9606.ENSP00000286398
PhosphoSite O95347
MaxQB O95347
PaxDb O95347
PRIDE O95347
Ensembl ENST00000286398
ENST00000374787
ENST00000374793
ENST00000493955
GeneID 10592
KEGG hsa:10592
UCSC uc004bbv.3
CTD 10592
GeneCards GC09P106856
H-InvDB HIX0008250
HGNC HGNC:14011
MIM 605576
neXtProt NX_O95347
PharmGKB PA37833
eggNOG COG1196
GeneTree ENSGT00550000074857
HOGENOM HOG000228249
HOVERGEN HBG106605
InParanoid O95347
KO K06674
OMA CQNGKIP
OrthoDB EOG7SR4KV
PhylomeDB O95347
TreeFam TF101157
Reactome REACT_150260
REACT_172744
ChiTaRS SMC2
GeneWiki SMC2
GenomeRNAi 10592
NextBio 40225
PRO PR:O95347
Proteomes UP000005640
Bgee O95347
CleanEx HS_SMC2
ExpressionAtlas O95347
Genevestigator O95347
GO GO:0000793
GO:0000796
GO:0005737
GO:0005829
GO:0070062
GO:0000228
GO:0005654
GO:0005634
GO:0005524
GO:0046982
GO:0051383
GO:0010032
GO:0045132
GO:0000278
GO:0007076
Gene3D 3.40.50.300
InterPro IPR027417
IPR003395
IPR024704
IPR027120
IPR010935
PANTHER PTHR18937:SF9
Pfam PF06470
PF02463
PIRSF PIRSF005719
SMART SM00968
SUPFAM SSF52540
SSF75553

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

part_of

GO:0070062

extracellular exosome

PMID:19056867[1]

ECO:0007005

high throughput direct assay evidence used in manual assertion

C

part_of:(UBERON:0001088)

Seeded From UniProt

complete

enables

GO:0046982

protein heterodimerization activity

PMID:9789013[2]

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:Q9NTJ3

F

Seeded From UniProt

complete

involved_in

GO:0007076

mitotic chromosome condensation

PMID:11136719[3]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

PMID:10958694[4]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

PMID:12589063[5]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

PMID:12589063[5]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0000796

condensin complex

PMID:10958694[4]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0000796

condensin complex

PMID:11136719[3]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0000793

condensed chromosome

PMID:12589063[5]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0000228

nuclear chromosome

PMID:10958694[4]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005730

nucleolus

GO_REF:0000052

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000052

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0051383

kinetochore organization

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q8CG48
ensembl:ENSMUSP00000099979

P

Seeded From UniProt

complete

involved_in

GO:0045132

meiotic chromosome segregation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q8CG48
ensembl:ENSMUSP00000099979

P

Seeded From UniProt

complete

involved_in

GO:0010032

meiotic chromosome condensation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q8CG48
ensembl:ENSMUSP00000099979

P

Seeded From UniProt

complete

enables

GO:0003697

single-stranded DNA binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q8CG48
ensembl:ENSMUSP00000099979

F

Seeded From UniProt

complete

part_of

GO:0000796

condensin complex

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q8CG48
ensembl:ENSMUSP00000099979

C

Seeded From UniProt

complete

part_of

GO:0000793

condensed chromosome

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q8CG48
ensembl:ENSMUSP00000099979

C

Seeded From UniProt

complete

enables

GO:0005524

ATP binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR010935
InterPro:IPR036277

F

Seeded From UniProt

complete

part_of

GO:0005694

chromosome

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR010935
InterPro:IPR036277

C

Seeded From UniProt

complete

involved_in

GO:0051276

chromosome organization

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR010935
InterPro:IPR036277

P

Seeded From UniProt

complete

involved_in

GO:0007076

mitotic chromosome condensation

PMID:9789013[2]

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005829

cytosol

Reactome:R-HSA-2529020
Reactome:R-HSA-2529015

ECO:0000304

author statement supported by traceable reference used in manual assertion


C

Seeded From UniProt

complete

part_of

GO:0005654

nucleoplasm

Reactome:R-HSA-2429719
Reactome:R-HSA-2294600
Reactome:R-HSA-2294590
Reactome:R-HSA-2294580
Reactome:R-HSA-2288097
Reactome:R-HSA-2172666

ECO:0000304

author statement supported by traceable reference used in manual assertion






C

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

part_of

GO:0005694

chromosome

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0158
UniProtKB-SubCell:SL-0468

C

Seeded From UniProt

complete

enables

GO:0000166

nucleotide binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0547

F

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0539
UniProtKB-SubCell:SL-0191

C

Seeded From UniProt

complete

enables

GO:0005524

ATP binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0067

F

Seeded From UniProt

complete

involved_in

GO:0030261

chromosome condensation

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0226

P

Seeded From UniProt

complete

involved_in

GO:0007049

cell cycle

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0131

P

Seeded From UniProt

complete

involved_in

GO:0051301

cell division

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0132

P

Seeded From UniProt

complete

edit table

Notes

References

See Help:References for how to manage references in GONUTS.

  1. ↑ Gonzales, PA et al. (2009) Large-scale proteomics and phosphoproteomics of urinary exosomes. J. Am. Soc. Nephrol. 20 363-79 PubMed GONUTS page
  2. ↑ 2.0 2.1 Schmiesing, JA et al. (1998) Identification of two distinct human SMC protein complexes involved in mitotic chromosome dynamics. Proc. Natl. Acad. Sci. U.S.A. 95 12906-11 PubMed GONUTS page
  3. ↑ 3.0 3.1 Kimura, K et al. (2001) Chromosome condensation by a human condensin complex in Xenopus egg extracts. J. Biol. Chem. 276 5417-20 PubMed GONUTS page
  4. ↑ 4.0 4.1 4.2 Schmiesing, JA et al. (2000) A human condensin complex containing hCAP-C-hCAP-E and CNAP1, a homolog of Xenopus XCAP-D2, colocalizes with phosphorylated histone H3 during the early stage of mitotic chromosome condensation. Mol. Cell. Biol. 20 6996-7006 PubMed GONUTS page
  5. ↑ 5.0 5.1 5.2 Przewloka, MR et al. (2003) In vitro and in vivo interactions of DNA ligase IV with a subunit of the condensin complex. Mol. Biol. Cell 14 685-97 PubMed GONUTS page
Retrieved from "https://gowiki.tamu.edu/wiki/index.php?title=HUMAN:SMC2&oldid=5942396"