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HUMAN:SHC4

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Species (Taxon ID) Homo sapiens (Human). (9606)
Gene Name(s) SHC4 (synonyms: SHCD)
Protein Name(s) SHC-transforming protein 4

Rai-like protein RaLP SHC-transforming protein D hShcD Src homology 2 domain-containing-transforming protein C4 SH2 domain protein C4

External Links
UniProt Q6S5L8
EMBL AY464565
AY358250
BC033907
CCDS CCDS10130.1
RefSeq NP_976224.3
XP_005254433.1
UniGene Hs.642615
ProteinModelPortal Q6S5L8
SMR Q6S5L8
BioGrid 134386
IntAct Q6S5L8
STRING 9606.ENSP00000329668
PhosphoSite Q6S5L8
DMDM 74722804
MaxQB Q6S5L8
PaxDb Q6S5L8
PRIDE Q6S5L8
Ensembl ENST00000332408
ENST00000396535
GeneID 399694
KEGG hsa:399694
UCSC uc001zxb.1
uc010uey.1
CTD 399694
GeneCards GC15M049115
H-InvDB HIX0202177
HGNC HGNC:16743
neXtProt NX_Q6S5L8
PharmGKB PA142670917
eggNOG NOG315087
GeneTree ENSGT00390000018860
HOGENOM HOG000231974
HOVERGEN HBG050121
InParanoid Q6S5L8
KO K17449
OMA PRMASMK
OrthoDB EOG7MD4QK
PhylomeDB Q6S5L8
TreeFam TF315807
SignaLink Q6S5L8
ChiTaRS SHC4
GenomeRNAi 399694
NextBio 105503
PRO PR:Q6S5L8
Proteomes UP000005640
Bgee Q6S5L8
CleanEx HS_SHC4
ExpressionAtlas Q6S5L8
Genevestigator Q6S5L8
GO GO:0030054
GO:0045211
GO:0006915
GO:0035556
GO:0008284
GO:0010468
GO:0048863
Gene3D 2.30.29.30
3.30.505.10
InterPro IPR011993
IPR006019
IPR006020
IPR000980
IPR029596
PANTHER PTHR10337:SF12
Pfam PF00640
PF00017
PRINTS PR00401
PR00629
SMART SM00462
SM00252
SUPFAM SSF55550
PROSITE PS01179
PS50001

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

enables

GO:0030971

receptor tyrosine kinase binding

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:2655364
MGI:MGI:98296
PANTHER:PTN000818658
RGD:620446

F

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000818658
RGD:620446
UniProtKB:P29353

C

Seeded From UniProt

complete

involved_in

GO:0048863

stem cell differentiation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q6S5L9
ensembl:ENSMUSP00000043146

P

Seeded From UniProt

complete

enables

GO:0030971

receptor tyrosine kinase binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q6S5L9
ensembl:ENSMUSP00000043146

F

Seeded From UniProt

complete

enables

GO:0019904

protein domain specific binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q6S5L9
ensembl:ENSMUSP00000043146

F

Seeded From UniProt

complete

involved_in

GO:0010468

regulation of gene expression

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q6S5L9
ensembl:ENSMUSP00000043146

P

Seeded From UniProt

complete

involved_in

GO:0008284

positive regulation of cell population proliferation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q6S5L9
ensembl:ENSMUSP00000043146

P

Seeded From UniProt

complete

involved_in

GO:0006915

apoptotic process

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q6S5L9
ensembl:ENSMUSP00000043146

P

Seeded From UniProt

complete

involved_in

GO:0008284

positive regulation of cell population proliferation

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR029596

P

Seeded From UniProt

complete

enables

GO:0030971

receptor tyrosine kinase binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR029596

F

Seeded From UniProt

complete

involved_in

GO:0035556

intracellular signal transduction

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR006019

P

Seeded From UniProt

complete

involved_in

GO:0048863

stem cell differentiation

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR029596

P

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-1003

C

Seeded From UniProt

complete

part_of

GO:0030054

cell junction

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0965

C

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

part_of

GO:0045202

synapse

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0770

C

Seeded From UniProt

complete

part_of

GO:0045211

postsynaptic membrane

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0628
UniProtKB-SubCell:SL-0219

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page