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HUMAN:RGS20
Contents
| Species (Taxon ID) | Homo sapiens (Human). (9606) | |
| Gene Name(s) | RGS20 (synonyms: RGSZ1, ZGAP1) | |
| Protein Name(s) | Regulator of G-protein signaling 20
RGS20 Gz-selective GTPase-activating protein G(z)GAP Gz-GAP Regulator of G-protein signaling Z1 Regulator of Gz-selective protein signaling 1 | |
| External Links | ||
| UniProt | O76081 | |
| EMBL | AF060877 AF366054 AF366055 AF366056 AF366057 AF074979 AF493940 BC015614 BC063490 AY046538 | |
| CCDS | CCDS6155.1 CCDS6156.1 CCDS69482.1 | |
| RefSeq | NP_001273602.1 NP_001273603.1 NP_001273604.1 NP_003693.2 NP_733466.1 | |
| UniGene | Hs.368733 | |
| ProteinModelPortal | O76081 | |
| SMR | O76081 | |
| BioGrid | 114161 | |
| IntAct | O76081 | |
| MINT | MINT-3002244 | |
| STRING | 9606.ENSP00000297313 | |
| PhosphoSite | O76081 | |
| MaxQB | O76081 | |
| PaxDb | O76081 | |
| PRIDE | O76081 | |
| DNASU | 8601 | |
| Ensembl | ENST00000276500 ENST00000297313 ENST00000344277 | |
| GeneID | 8601 | |
| KEGG | hsa:8601 | |
| UCSC | uc003xrp.3 uc003xrq.3 uc010lye.3 uc010lyf.3 | |
| CTD | 8601 | |
| GeneCards | GC08P054764 | |
| HGNC | HGNC:14600 | |
| MIM | 607193 | |
| neXtProt | NX_O76081 | |
| PharmGKB | PA34373 | |
| eggNOG | NOG258376 | |
| GeneTree | ENSGT00760000118903 | |
| HOGENOM | HOG000233513 | |
| HOVERGEN | HBG013233 | |
| InParanoid | O76081 | |
| KO | K16449 | |
| OMA | RQMPAAQ | |
| OrthoDB | EOG7SN8DQ | |
| PhylomeDB | O76081 | |
| TreeFam | TF315837 | |
| Reactome | REACT_19231 REACT_19333 | |
| ChiTaRS | RGS20 | |
| GeneWiki | RGS20 | |
| GenomeRNAi | 8601 | |
| NextBio | 32227 | |
| PRO | PR:O76081 | |
| Proteomes | UP000005640 | |
| Bgee | O76081 | |
| CleanEx | HS_RGS20 | |
| ExpressionAtlas | O76081 | |
| Genevestigator | O76081 | |
| GO | GO:0005737 GO:0005634 GO:0005886 GO:0005096 GO:0043547 GO:0008277 GO:0038032 | |
| Gene3D | 1.10.196.10 | |
| InterPro | IPR016137 IPR024066 | |
| Pfam | PF00615 | |
| PRINTS | PR01301 | |
| SMART | SM00315 | |
| SUPFAM | SSF48097 | |
| PROSITE | PS50132 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
part_of |
GO:0005802 |
trans-Golgi network |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
| GO:0005737 |
cytoplasm |
ECO:0000315 |
C |
Fig.12 |
complete | |||||
|
involved_in |
GO:0043547 |
positive regulation of GTPase activity |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0005096 |
P |
Seeded From UniProt |
complete | ||
| GO:0005802 |
trans-Golgi network |
ECO:0000315 |
C |
Fig.12 |
complete | |||||
|
involved_in |
GO:0008277 |
regulation of G protein-coupled receptor signaling pathway |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005096 |
GTPase activator activity |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0007186 |
G protein-coupled receptor signaling pathway |
Reactome:R-HSA-388396 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005886 |
plasma membrane |
Reactome:R-HSA-8982021 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
|
C |
Seeded From UniProt |
complete | |
|
enables |
GO:0003924 |
GTPase activity |
Reactome:R-HSA-8982021 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
|
F |
Seeded From UniProt |
complete | |
|
involved_in |
GO:0009968 |
negative regulation of signal transduction |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016020 |
membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 Chatterjee, TK & Fisher, RA (2000) Cytoplasmic, nuclear, and golgi localization of RGS proteins. Evidence for N-terminal and RGS domain sequences as intracellular targeting motifs. J. Biol. Chem. 275 24013-21 PubMed GONUTS page
- ↑ 2.0 2.1 Glick, JL et al. (1998) RGSZ1, a Gz-selective regulator of G protein signaling whose action is sensitive to the phosphorylation state of Gzalpha. J. Biol. Chem. 273 26008-13 PubMed GONUTS page
