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HUMAN:RET3

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Species (Taxon ID) Homo sapiens (Human). (9606)
Gene Name(s) RBP3
Protein Name(s) Retinol-binding protein 3

Interphotoreceptor retinoid-binding protein IRBP Interstitial retinol-binding protein

External Links
UniProt P10745
EMBL M33875
M33864
M33865
M33866
M22453
J05253
AB593121
AL731561
CH471251
BC039844
J03912
X53044
DQ426897
CCDS CCDS73119.1
PIR A33812
RefSeq NP_002891.1
UniGene Hs.591928
ProteinModelPortal P10745
SMR P10745
BioGrid 111883
STRING 9606.ENSP00000224600
DrugBank DB00162
MEROPS S41.950
PhosphoSite P10745
DMDM 124894
PaxDb P10745
PRIDE P10745
Ensembl ENST00000584701
GeneID 5949
KEGG hsa:5949
UCSC uc001jez.3
CTD 5949
GeneCards GC10M048381
GeneReviews RBP3
HGNC HGNC:9921
MIM 180290
615233
neXtProt NX_P10745
Orphanet 791
PharmGKB PA34288
eggNOG NOG76669
GeneTree ENSGT00390000014726
HOGENOM HOG000139907
HOVERGEN HBG006175
InParanoid P10745
OMA CSYFFDE
OrthoDB EOG7MPRD1
PhylomeDB P10745
TreeFam TF332253
BioCyc MetaCyc:ENSG00000107618-MONOMER
Reactome REACT_160083
REACT_160156
GeneWiki RBP3
GenomeRNAi 5949
NextBio 23178
PRO PR:P10745
Proteomes UP000005640
Bgee P10745
CleanEx HS_RBP3
Genevestigator P10745
GO GO:0005576
GO:0005615
GO:0033165
GO:0031982
GO:0016918
GO:0005501
GO:0019841
GO:0008236
GO:0006629
GO:0007603
GO:0001523
GO:0006810
GO:0007601
Gene3D 3.90.226.10
InterPro IPR029045
IPR005151
Pfam PF03572
SMART SM00245
SUPFAM SSF52096

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

part_of

GO:1903561

extracellular vesicle

PMID:24769233[1]

ECO:0007005

high throughput direct assay evidence used in manual assertion

C

part_of:(UBERON:0001359)

Seeded From UniProt

complete

part_of

GO:0005615

extracellular space

PMID:23486466[2]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0090658

cone matrix sheath

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000137262
UniProtKB:F1NA61
UniProtKB:F1SEL7

C

Seeded From UniProt

complete

enables

GO:0019841

retinol binding

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000137262
RGD:3545

F

Seeded From UniProt

complete

part_of

GO:0033165

interphotoreceptor matrix

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:G3V8Q4
ensembl:ENSRNOP00000068670

C

Seeded From UniProt

complete

enables

GO:0019841

retinol binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:G3V8Q4
ensembl:ENSRNOP00000068670

F

Seeded From UniProt

complete

enables

GO:0005501

retinoid binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR032956

F

Seeded From UniProt

complete

involved_in

GO:0006508

proteolysis

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR005151

P

Seeded From UniProt

complete

involved_in

GO:0007601

visual perception

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR032956

P

Seeded From UniProt

complete

enables

GO:0008236

serine-type peptidase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR005151

F

Seeded From UniProt

complete

involved_in

GO:0007601

visual perception

PMID:2542268[4]

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0006629

lipid metabolic process

PMID:2542268[4]

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0005501

retinoid binding

PMID:2542268[4]
Reactome:R-HSA-2465938
Reactome:R-HSA-2465934
Reactome:R-HSA-2464809
Reactome:R-HSA-2454113

ECO:0000304

author statement supported by traceable reference used in manual assertion





F

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

Reactome:R-HSA-2465938
Reactome:R-HSA-2465934
Reactome:R-HSA-2464809
Reactome:R-HSA-2454113

ECO:0000304

author statement supported by traceable reference used in manual assertion




C

Seeded From UniProt

complete

involved_in

GO:0001523

retinoid metabolic process

Reactome:R-HSA-2453902
Reactome:R-HSA-2187335

ECO:0000304

author statement supported by traceable reference used in manual assertion


P

Seeded From UniProt

complete

enables

GO:0016918

retinal binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0845

F

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0964

C

Seeded From UniProt

complete

part_of

GO:0033165

interphotoreceptor matrix

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0146

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Chiasserini, D et al. (2014) Proteomic analysis of cerebrospinal fluid extracellular vesicles: a comprehensive dataset. J Proteomics 106 191-204 PubMed GONUTS page
  2. Li, S et al. (2013) Secretory defect and cytotoxicity: the potential disease mechanisms for the retinitis pigmentosa (RP)-associated interphotoreceptor retinoid-binding protein (IRBP). J. Biol. Chem. 288 11395-406 PubMed GONUTS page
  3. 3.0 3.1 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
  4. 4.0 4.1 4.2 Liou, GI et al. (1989) Human interstitial retinoid-binding protein. Gene structure and primary structure. J. Biol. Chem. 264 8200-6 PubMed GONUTS page