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HUMAN:RBM7

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Species (Taxon ID) Homo sapiens (Human). (9606)
Gene Name(s) RBM7
Protein Name(s) RNA-binding protein 7

RNA-binding motif protein 7

External Links
UniProt Q9Y580
EMBL AF156098
AK002015
AK312619
CH471065
BC034381
CCDS CCDS8370.1
RefSeq NP_001272974.1
NP_001272975.1
NP_001272976.1
NP_001272977.1
NP_057174.1
UniGene Hs.7527
PDB 2M8H
5IQQ
5LXR
5LXY
PDBsum 2M8H
5IQQ
5LXR
5LXY
ProteinModelPortal Q9Y580
SMR Q9Y580
BioGrid 115478
DIP DIP-48833N
IntAct Q9Y580
MINT MINT-1453692
STRING 9606.ENSP00000439918
iPTMnet Q9Y580
PhosphoSitePlus Q9Y580
DMDM 9978697
EPD Q9Y580
MaxQB Q9Y580
PaxDb Q9Y580
PeptideAtlas Q9Y580
PRIDE Q9Y580
DNASU 10179
Ensembl ENST00000540163
GeneID 10179
KEGG hsa:10179
UCSC uc001pov.5
CTD 10179
DisGeNET 10179
GeneCards RBM7
HGNC HGNC:9904
HPA HPA013993
HPA048003
MIM 612413
neXtProt NX_Q9Y580
OpenTargets ENSG00000076053
PharmGKB PA34269
eggNOG KOG4454
ENOG41123B7
GeneTree ENSGT00870000136493
HOGENOM HOG000059553
HOVERGEN HBG009324
InParanoid Q9Y580
KO K13188
PhylomeDB Q9Y580
TreeFam TF323596
GeneWiki RBM7
GenomeRNAi 10179
PRO PR:Q9Y580
Proteomes UP000005640
Bgee ENSG00000076053
CleanEx HS_RBM7
ExpressionAtlas Q9Y580
Genevisible Q9Y580
GO GO:0005634
GO:0000166
GO:0003723
GO:0003727
GO:0051321
GO:0000381
CDD cd12592
Gene3D 3.30.70.330
InterPro IPR012677
IPR034500
IPR000504
Pfam PF00076
SMART SM00360
SUPFAM SSF54928
PROSITE PS50102

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0000381

regulation of alternative mRNA splicing, via spliceosome

PMID:27905398[1]

ECO:0000315

P

Provides regulation for the process of alternative splicing through interacting with spliceosome proteins.

complete
CACAO 12857

part_of

GO:0005654

nucleoplasm

PMID:16263084[2]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

NOT|part_of

GO:0005730

nucleolus

PMID:21855801[3]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

PMID:21855801[3]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0003723

RNA binding

PMID:22681889[4]

ECO:0007005

high throughput direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0003723

RNA binding

PMID:22658674[5]

ECO:0007005

high throughput direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

PMID:21873635[6]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001012985
UniProtKB:P57052

C

Seeded From UniProt

complete

enables

GO:0003727

single-stranded RNA binding

PMID:21873635[6]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001012985
WB:WBGene00020091

F

Seeded From UniProt

complete

involved_in

GO:0000381

regulation of alternative mRNA splicing, via spliceosome

PMID:21873635[6]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001012985
UniProtKB:P57052

P

Seeded From UniProt

complete

part_of

GO:0005654

nucleoplasm

GO_REF:0000052

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000052

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0003676

nucleic acid binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000504
InterPro:IPR035979

F

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0539
UniProtKB-SubCell:SL-0191

C

Seeded From UniProt

complete

enables

GO:0003723

RNA binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0694

F

Seeded From UniProt

complete

involved_in

GO:0051321

meiotic cell cycle

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0469

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Falk, S et al. (2016) Structure of the RBM7-ZCCHC8 core of the NEXT complex reveals connections to splicing factors. Nat Commun 7 13573 PubMed GONUTS page
  2. Gustafson, MP et al. (2005) Zcchc8 is a glycogen synthase kinase-3 substrate that interacts with RNA-binding proteins. Biochem. Biophys. Res. Commun. 338 1359-67 PubMed GONUTS page
  3. 3.0 3.1 Lubas, M et al. (2011) Interaction profiling identifies the human nuclear exosome targeting complex. Mol. Cell 43 624-37 PubMed GONUTS page
  4. Baltz, AG et al. (2012) The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts. Mol. Cell 46 674-90 PubMed GONUTS page
  5. Castello, A et al. (2012) Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. Cell 149 1393-406 PubMed GONUTS page
  6. 6.0 6.1 6.2 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page