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HUMAN:Q9BXH2

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Species (Taxon ID) Homo sapiens (Human). (9606)
Gene Name(s) STAT3 (ECO:0000313 with EMBL:AAK17196.1)
Protein Name(s) STAT3 (ECO:0000313 with EMBL:AAK17196.1)
External Links
UniProt Q9BXH2
EMBL AF332508
UniGene Hs.463059
IntAct Q9BXH2
MINT MINT-4938158
ChiTaRS STAT3
GO GO:0005634
GO:0003700
GO:0004871
InterPro IPR001217
PANTHER PTHR11801

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0045605

negative regulation of epidermal cell differentiation

PMID:22417306[1]

ECO:0000314

P

Figure 4 shows that knock-down of STAT3 expression triggers cell differentiation.

complete
CACAO 4876

enables

GO:0003700

DNA-binding transcription factor activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001217

F

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001217

C

Seeded From UniProt

complete

involved_in

GO:0006355

regulation of transcription, DNA-templated

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001217

P

Seeded From UniProt

complete

involved_in

GO:0007165

signal transduction

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001217

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Saeki, Y et al. (2012) An ErbB receptor-mediated AP-1 regulatory network is modulated by STAT3 and c-MYC during calcium-dependent keratinocyte differentiation. Exp. Dermatol. 21 293-8 PubMed GONUTS page