HUMAN:Q96QB2

Species (Taxon ID)	Homo sapiens (Human). (9606)
Gene Name(s)	lat1 (ECO:0000313 with EMBL:BAB70708.1)
Protein Name(s)	Sodium-independent neutral amino acid transporter LAT1 (ECO:0000313 with EMBL:BAB70708.1)
External Links
UniProt	Q96QB2
EMBL	AB023721
UniGene	Hs.513797
PRIDE	Q96QB2
HOVERGEN	HBG000476
GO	GO:0016021 GO:0015171
InterPro	IPR002293 IPR004760
PANTHER	PTHR11785
Pfam	PF13520
PIRSF	PIRSF006060
TIGRFAMs	TIGR00911

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
	GO:0015804	neutral amino acid transport	PMID:24671056	ECO:0000315			P		Figure 1B shows how when JPH203, a LAT-1 specific inhibitor was used then the amount of the neutral amino acid leucine was decreased. This shows how when LAT-1 is functional LAT1 acts to support effective uptake of amino acids, which is critical for the optimal function of HUVECs for angiogenesis.	complete CACAO 10003
involved_in	GO:0015804	neutral amino acid transport	PMID:24671056	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0006865	amino acid transport	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR004760	P		Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR002293	C		Seeded From UniProt	complete
part_of	GO:0016021	integral component of membrane	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR004760	C		Seeded From UniProt	complete
enables	GO:0022857	transmembrane transporter activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR002293	F		Seeded From UniProt	complete
involved_in	GO:0055085	transmembrane transport	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR002293	P		Seeded From UniProt	complete
part_of	GO:0016021	integral component of membrane	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0812	C		Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0472	C		Seeded From UniProt	complete
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References

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