HUMAN:PTBP2

Species (Taxon ID)	Homo sapiens (Human). (9606)
Gene Name(s)	PTBP2 (synonyms: NPTB, PTB, PTBLP)
Protein Name(s)	Polypyrimidine tract-binding protein 2 Neural polypyrimidine tract-binding protein Neurally-enriched homolog of PTB PTB-like protein
External Links
UniProt	Q9UKA9
EMBL	AF176085 AB051232 AB051233 AF530580 AF530581 AF530582 AF530583 BK000526 AL357150 AL357150 AL357150 AL357150 BC016582
CCDS	CCDS72828.1 CCDS72829.1 CCDS72830.1 CCDS754.1
RefSeq	NP_001287914.1 NP_001287915.1 NP_001287916.1 NP_001287917.1 NP_001287918.1 NP_001287919.1 NP_067013.1
UniGene	Hs.596061 Hs.743449
PDB	2CQ1 2MJU 4CQ1
PDBsum	2CQ1 2MJU 4CQ1
ProteinModelPortal	Q9UKA9
SMR	Q9UKA9
BioGrid	121796
IntAct	Q9UKA9
MINT	MINT-1483252
STRING	9606.ENSP00000412788
iPTMnet	Q9UKA9
PhosphoSitePlus	Q9UKA9
SwissPalm	Q9UKA9
BioMuta	PTBP2
DMDM	74761983
REPRODUCTION-2DPAGE	IPI00647067
EPD	Q9UKA9
PaxDb	Q9UKA9
PeptideAtlas	Q9UKA9
PRIDE	Q9UKA9
DNASU	58155
Ensembl	ENST00000370197 ENST00000370198 ENST00000426398 ENST00000609116
GeneID	58155
KEGG	hsa:58155
UCSC	uc001drn.3
CTD	58155
DisGeNET	58155
GeneCards	PTBP2
HGNC	HGNC:17662
HPA	HPA047420
MIM	608449
neXtProt	NX_Q9UKA9
OpenTargets	ENSG00000117569
PharmGKB	PA33935
eggNOG	KOG1190 ENOG410XPMZ
GeneTree	ENSGT00550000074508
HOVERGEN	HBG069548
InParanoid	Q9UKA9
KO	K14948
OMA	NLGESHH
OrthoDB	EOG091G0Z5R
PhylomeDB	Q9UKA9
TreeFam	TF319824
ChiTaRS	PTBP2
EvolutionaryTrace	Q9UKA9
GeneWiki	PTBP2
GenomeRNAi	58155
PRO	PR:Q9UKA9
Proteomes	UP000005640
Bgee	ENSG00000117569
CleanEx	HS_PTBP2
Genevisible	Q9UKA9
GO	GO:0030426 GO:0043025 GO:0005681 GO:0003729 GO:0000166 GO:0036002 GO:0003723 GO:0021549 GO:0006376 GO:0033119 GO:2000177 GO:0021510
Gene3D	3.30.70.330
InterPro	IPR006536 IPR012677 IPR000504
Pfam	PF00076
SMART	SM00360
SUPFAM	SSF54928
TIGRFAMs	TIGR01649
PROSITE	PS50102

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
enables	GO:0003723	RNA binding	PMID:22681889	ECO:0007005	high throughput direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
	GO:0006376	mRNA splice site selection	PMID:27926877	ECO:0000314			P		Provides regulation of negative regulation of the splicing of exons during mRNA splicing.	complete CACAO 12852
enables	GO:0003723	RNA binding	PMID:22658674	ECO:0007005	high throughput direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
involved_in	GO:0033119	negative regulation of RNA splicing	PMID:18335065	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0043025	neuronal cell body	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q66H20 ensembl:ENSRNOP00000015036	C		Seeded From UniProt	complete
involved_in	GO:0033119	negative regulation of RNA splicing	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q66H20 ensembl:ENSRNOP00000015036	P		Seeded From UniProt	complete
part_of	GO:0030426	growth cone	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q66H20 ensembl:ENSRNOP00000015036	C		Seeded From UniProt	complete
involved_in	GO:0021549	cerebellum development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q66H20 ensembl:ENSRNOP00000015036	P		Seeded From UniProt	complete
involved_in	GO:0021510	spinal cord development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q66H20 ensembl:ENSRNOP00000015036	P		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q66H20 ensembl:ENSRNOP00000015036	C		Seeded From UniProt	complete
involved_in	GO:2000177	regulation of neural precursor cell proliferation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q91Z31 ensembl:ENSMUSP00000029780	P		Seeded From UniProt	complete
involved_in	GO:0006376	mRNA splice site selection	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q91Z31 ensembl:ENSMUSP00000029780	P		Seeded From UniProt	complete
part_of	GO:0005681	spliceosomal complex	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q91Z31 ensembl:ENSMUSP00000029780	C		Seeded From UniProt	complete
enables	GO:0003729	mRNA binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q91Z31 ensembl:ENSMUSP00000029780	F		Seeded From UniProt	complete
enables	GO:0003676	nucleic acid binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000504 InterPro:IPR035979	F		Seeded From UniProt	complete
enables	GO:0003723	RNA binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR006536	F		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR006536	C		Seeded From UniProt	complete
involved_in	GO:0006397	mRNA processing	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR006536	P		Seeded From UniProt	complete
involved_in	GO:0006397	mRNA processing	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0507	P		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0539 UniProtKB-SubCell:SL-0191	C		Seeded From UniProt	complete
involved_in	GO:0008380	RNA splicing	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0508	P		Seeded From UniProt	complete
enables	GO:0003723	RNA binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0694	F		Seeded From UniProt	complete
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References

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