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HUMAN:PGK2

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Species (Taxon ID) Homo sapiens (Human). (9606)
Gene Name(s) PGK2 (synonyms: PGKB)
Protein Name(s) Phosphoglycerate kinase 2

Phosphoglycerate kinase, testis specific

External Links
UniProt P07205
EMBL X05246
AK312770
AL121974
BC038843
CCDS CCDS4930.1
PIR A24030
A27816
RefSeq NP_620061.2
UniGene Hs.367727
ProteinModelPortal P07205
SMR P07205
BioGrid 111253
STRING 9606.ENSP00000305995
ChEMBL CHEMBL2096677
PhosphoSite P07205
DMDM 21264485
UCD-2DPAGE P07205
MaxQB P07205
PaxDb P07205
PeptideAtlas P07205
PRIDE P07205
DNASU 5232
Ensembl ENST00000304801
GeneID 5232
KEGG hsa:5232
UCSC uc003ozu.3
CTD 5232
GeneCards GC06M049753
HGNC HGNC:8898
HPA HPA045385
MIM 172270
neXtProt NX_P07205
PharmGKB PA33237
eggNOG COG0126
GeneTree ENSGT00390000008820
HOGENOM HOG000227107
HOVERGEN HBG008177
InParanoid P07205
KO K00927
OMA ESNKNHA
OrthoDB EOG74R1QN
PhylomeDB P07205
TreeFam TF300489
BioCyc MetaCyc:HS10215-MONOMER
UniPathway UPA00109
GenomeRNAi 5232
NextBio 20224
PRO PR:P07205
Proteomes UP000005640
Bgee P07205
CleanEx HS_PGK2
Genevestigator P07205
GO GO:0005737
GO:0070062
GO:0005634
GO:0035686
GO:0005524
GO:0004618
GO:0006096
GO:0016310
GO:0030317
Gene3D 3.40.50.1260
3.40.50.1270
HAMAP MF_00145
InterPro IPR001576
IPR015901
IPR015911
IPR015824
PANTHER PTHR11406
Pfam PF00162
PIRSF PIRSF000724
PRINTS PR00477
SUPFAM SSF53748
PROSITE PS00111

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

part_of

GO:0070062

extracellular exosome

PMID:23533145[1]

ECO:0007005

high throughput direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

PMID:21630459[2]

ECO:0007005

high throughput direct assay evidence used in manual assertion

C

part_of:(CL:0000019)

Seeded From UniProt

complete

involved_in

GO:0016310

phosphorylation

PMID:3453121[3]

ECO:0000303

author statement without traceable support used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0016310

phosphorylation

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P41759

P

Seeded From UniProt

complete

involved_in

GO:0006096

glycolytic process

PMID:3453121[3]

ECO:0000303

author statement without traceable support used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0005524

ATP binding

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P00559

F

Seeded From UniProt

complete

enables

GO:0004618

phosphoglycerate kinase activity

PMID:3453121[3]

ECO:0000303

author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0004618

phosphoglycerate kinase activity

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P41759

F

Seeded From UniProt

complete

involved_in

GO:1903862

positive regulation of oxidative phosphorylation

PMID:21873635[4]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000150497
ZFIN:ZDB-GENE-040426-2711

P

Seeded From UniProt

complete

enables

GO:0043531

ADP binding

PMID:21873635[4]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000150497
RGD:619878

F

Seeded From UniProt

complete

part_of

GO:0035686

sperm fibrous sheath

PMID:21873635[4]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:97563
PANTHER:PTN001685897

C

Seeded From UniProt

complete

involved_in

GO:0006096

glycolytic process

PMID:21873635[4]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG10703
MGI:MGI:97555
MGI:MGI:97563
PANTHER:PTN000150497
RGD:619878
SGD:S000000605
TAIR:locus:2206410
UniProtKB:P00558
UniProtKB:P50318

P

Seeded From UniProt

complete

involved_in

GO:0006094

gluconeogenesis

PMID:21873635[4]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000150497
RGD:619878
SGD:S000000605

P

Seeded From UniProt

complete

part_of

GO:0005829

cytosol

PMID:21873635[4]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG10703
PANTHER:PTN000150497
RGD:619878
TAIR:locus:2087750
TAIR:locus:2206410

C

Seeded From UniProt

complete

enables

GO:0005524

ATP binding

PMID:21873635[4]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000150497
RGD:619878
UniProtKB:P00559

F

Seeded From UniProt

complete

enables

GO:0004618

phosphoglycerate kinase activity

PMID:21873635[4]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG10703
MGI:MGI:97555
MGI:MGI:97563
PANTHER:PTN000150497
RGD:619878
SGD:S000000605
UniProtKB:P00558
UniProtKB:P11977

F

Seeded From UniProt

complete

part_of

GO:0035686

sperm fibrous sheath

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P09041
ensembl:ENSMUSP00000033585

C

Seeded From UniProt

complete

involved_in

GO:0030317

flagellated sperm motility

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P09041
ensembl:ENSMUSP00000033585

P

Seeded From UniProt

complete

involved_in

GO:0006096

glycolytic process

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P09041
ensembl:ENSMUSP00000033585

P

Seeded From UniProt

complete

part_of

GO:0005929

cilium

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P09041
ensembl:ENSMUSP00000033585

C

Seeded From UniProt

complete

enables

GO:0004618

phosphoglycerate kinase activity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P09041
ensembl:ENSMUSP00000033585

F

Seeded From UniProt

complete

enables

GO:0004618

phosphoglycerate kinase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001576
InterPro:IPR015824
InterPro:IPR015911
InterPro:IPR036043

F

Seeded From UniProt

complete

involved_in

GO:0006096

glycolytic process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001576
InterPro:IPR015824
InterPro:IPR015911
InterPro:IPR036043

P

Seeded From UniProt

complete

enables

GO:0004618

phosphoglycerate kinase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:2.7.2.3

F

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

enables

GO:0016301

kinase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0418

F

Seeded From UniProt

complete

enables

GO:0000166

nucleotide binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0547

F

Seeded From UniProt

complete

enables

GO:0005524

ATP binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0067

F

Seeded From UniProt

complete

involved_in

GO:0006096

glycolytic process

GO_REF:0000037
GO_REF:0000041

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0324
UniPathway:UPA00109

P

Seeded From UniProt

complete

enables

GO:0016740

transferase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0808

F

Seeded From UniProt

complete

involved_in

GO:0016310

phosphorylation

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0418

P

Seeded From UniProt

complete

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Notes

References

See Help:References for how to manage references in GONUTS.

  1. ↑ Principe, S et al. (2013) In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine. Proteomics 13 1667-71 PubMed GONUTS page
  2. ↑ de Mateo, S et al. (2011) Proteomic characterization of the human sperm nucleus. Proteomics 11 2714-26 PubMed GONUTS page
  3. ↑ 3.0 3.1 3.2 McCarrey, JR & Thomas, K () Human testis-specific PGK gene lacks introns and possesses characteristics of a processed gene. Nature 326 501-5 PubMed GONUTS page
  4. ↑ 4.0 4.1 4.2 4.3 4.4 4.5 4.6 4.7 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
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