GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.
HUMAN:PEPL
Contents
Species (Taxon ID) | Homo sapiens (Human). (9606) | |
Gene Name(s) | PPL (synonyms: KIAA0568) | |
Protein Name(s) | Periplakin
190 kDa paraneoplastic pemphigus antigen 195 kDa cornified envelope precursor protein | |
External Links | ||
UniProt | O60437 | |
EMBL | AF001691 AF013717 AF041004 AF040999 AF041000 AF041002 AF041003 AC027687 CH471112 BC114620 AB011140 | |
CCDS | CCDS10526.1 | |
PIR | T00337 | |
RefSeq | NP_002696.3 | |
UniGene | Hs.192233 | |
PDB | 4Q28 | |
PDBsum | 4Q28 | |
ProteinModelPortal | O60437 | |
SMR | O60437 | |
BioGrid | 111488 | |
IntAct | O60437 | |
MINT | MINT-1181651 | |
STRING | 9606.ENSP00000340510 | |
PhosphoSite | O60437 | |
MaxQB | O60437 | |
PaxDb | O60437 | |
PRIDE | O60437 | |
Ensembl | ENST00000345988 | |
GeneID | 5493 | |
KEGG | hsa:5493 | |
UCSC | uc002cyd.1 | |
CTD | 5493 | |
GeneCards | GC16M004932 | |
H-InvDB | HIX0012794 | |
HGNC | HGNC:9273 | |
HPA | HPA042550 | |
MIM | 602871 | |
neXtProt | NX_O60437 | |
PharmGKB | PA33602 | |
eggNOG | NOG280386 | |
GeneTree | ENSGT00760000119163 | |
HOGENOM | HOG000168302 | |
HOVERGEN | HBG053564 | |
InParanoid | O60437 | |
KO | K10386 | |
OMA | LPLVDHQ | |
OrthoDB | EOG7XM2WT | |
PhylomeDB | O60437 | |
TreeFam | TF342779 | |
GeneWiki | Periplakin | |
GenomeRNAi | 5493 | |
NextBio | 21238 | |
PRO | PR:O60437 | |
Proteomes | UP000005640 | |
Bgee | O60437 | |
CleanEx | HS_PPL | |
ExpressionAtlas | O60437 | |
Genevestigator | O60437 | |
GO | GO:0005856 GO:0030057 GO:0070062 GO:0005739 GO:0005634 GO:0005886 GO:0005200 GO:0031424 | |
InterPro | IPR001101 IPR018159 | |
Pfam | PF00681 | |
SMART | SM00250 SM00150 | |
SUPFAM | SSF75399 |
Annotations
Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
---|---|---|---|---|---|---|---|---|---|---|
enables |
GO:0045296 |
cadherin binding |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0009612 |
response to mechanical stimulus |
ECO:0000270 |
expression pattern evidence used in manual assertion |
P |
|
Seeded From UniProt |
complete | ||
part_of |
GO:0070062 |
extracellular exosome |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
C |
part_of:(UBERON:0001831) |
Seeded From UniProt |
complete | ||
part_of |
GO:0070062 |
extracellular exosome |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
C |
part_of:(UBERON:0001088) |
Seeded From UniProt |
complete | ||
involved_in |
GO:0045104 |
intermediate filament cytoskeleton organization |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:109611 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0042060 |
wound healing |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:108559 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0016020 |
membrane |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:104627 |
C |
Seeded From UniProt |
complete | ||
colocalizes_with |
GO:0005882 |
intermediate filament |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:109611 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0005737 |
cytoplasm |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:104627 |
C |
Seeded From UniProt |
complete | ||
enables |
GO:0005198 |
structural molecule activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN002753757 |
F |
Seeded From UniProt |
complete | ||
part_of |
GO:0005856 |
cytoskeleton |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005856 |
cytoskeleton |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
C |
Seeded From UniProt |
complete | |||
enables |
GO:0005200 |
structural constituent of cytoskeleton |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0070268 |
cornification |
Reactome:R-HSA-6809371 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0005829 |
cytosol |
Reactome:R-HSA-8938431 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
|
C |
Seeded From UniProt |
complete | |
part_of |
GO:0001533 |
cornified envelope |
Reactome:R-HSA-6814764 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0005856 |
cytoskeleton |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0030054 |
cell junction |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005634 |
nucleus |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005886 |
plasma membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0016020 |
membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005737 |
cytoplasm |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0031424 |
keratinization |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0005739 |
mitochondrion |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0030057 |
desmosome |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Guo, Z et al. (2014) E-cadherin interactome complexity and robustness resolved by quantitative proteomics. Sci Signal 7 rs7 PubMed GONUTS page
- ↑ Pyle, AL et al. () Biomechanical stress induces novel arterial intima-enriched genes: implications for vascular adaptation to stress. Cardiovasc. Pathol. 19 e13-20 PubMed GONUTS page
- ↑ Gonzalez-Begne, M et al. (2009) Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT). J. Proteome Res. 8 1304-14 PubMed GONUTS page
- ↑ Gonzales, PA et al. (2009) Large-scale proteomics and phosphoproteomics of urinary exosomes. J. Am. Soc. Nephrol. 20 363-79 PubMed GONUTS page
- ↑ 5.0 5.1 5.2 5.3 5.4 5.5 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
- ↑ 6.0 6.1 Aho, S et al. (1998) cDNA cloning, mRNA expression, and chromosomal mapping of human and mouse periplakin genes. Genomics 48 242-7 PubMed GONUTS page