GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.

Have any questions? Please email us at ecoliwiki@gmail.com

HUMAN:ORC6

From GONUTS
Jump to: navigation, search
Species (Taxon ID) Homo sapiens (Human). (9606)
Gene Name(s) ORC6 (synonyms: ORC6L)
Protein Name(s) Origin recognition complex subunit 6
External Links
UniProt Q9Y5N6
EMBL AF139658
AK024019
CH471092
BC039032
BC063565
CCDS CCDS10722.1
RefSeq NP_055136.1
UniGene Hs.49760
PDB 3M03
PDBsum 3M03
ProteinModelPortal Q9Y5N6
SMR Q9Y5N6
BioGrid 117129
DIP DIP-29692N
IntAct Q9Y5N6
MINT MINT-1202310
STRING 9606.ENSP00000219097
PhosphoSite Q9Y5N6
DMDM 8928274
MaxQB Q9Y5N6
PaxDb Q9Y5N6
PRIDE Q9Y5N6
DNASU 23594
Ensembl ENST00000219097
GeneID 23594
KEGG hsa:23594
UCSC uc002eeg.1
CTD 23594
GeneCards GC16P046724
HGNC HGNC:17151
HPA CAB016330
MIM 607213
613803
neXtProt NX_Q9Y5N6
Orphanet 2554
PharmGKB PA32813
eggNOG NOG285438
GeneTree ENSGT00390000007370
HOGENOM HOG000065679
HOVERGEN HBG007876
InParanoid Q9Y5N6
KO K02608
OMA VEIPHKP
PhylomeDB Q9Y5N6
TreeFam TF101096
Reactome REACT_1095
REACT_1156
REACT_1321
REACT_1707
REACT_1949
REACT_207
REACT_2243
REACT_567
REACT_6769
ChiTaRS ORC6
GeneWiki ORC6
ORC6L
GenomeRNAi 23594
NextBio 46248
PRO PR:Q9Y5N6
Proteomes UP000005640
Bgee Q9Y5N6
CleanEx HS_ORC6L
ExpressionAtlas Q9Y5N6
Genevestigator Q9Y5N6
GO GO:0016020
GO:0005664
GO:0005654
GO:0000808
GO:0003677
GO:0006260
GO:0006261
GO:0000082
GO:0000278
InterPro IPR008721
IPR020529
Pfam PF05460
ProDom PD315657

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0051782

negative regulation of cell division

PMID:22581055[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0016020

membrane

PMID:19946888[2]

ECO:0007005

high throughput direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0000808

origin recognition complex

PMID:17716973[3]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0006270

DNA replication initiation

PMID:21873635[4]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0023180
PANTHER:PTN000333607

P

Seeded From UniProt

complete

part_of

GO:0005664

nuclear origin of replication recognition complex

PMID:21873635[4]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0023180
PANTHER:PTN000333607
PomBase:SPBC2A9.12

C

Seeded From UniProt

complete

enables

GO:0003688

DNA replication origin binding

PMID:21873635[4]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000333607
PomBase:SPBC2A9.12

F

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000052

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0001650

fibrillar center

GO_REF:0000052

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR008721

F

Seeded From UniProt

complete

part_of

GO:0005664

nuclear origin of replication recognition complex

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR008721
InterPro:IPR020529

C

Seeded From UniProt

complete

involved_in

GO:0006260

DNA replication

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR008721
InterPro:IPR020529

P

Seeded From UniProt

complete

involved_in

GO:0006260

DNA replication

Reactome:R-HSA-176318

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005654

nucleoplasm

Reactome:R-HSA-68944
Reactome:R-HSA-68940
Reactome:R-HSA-68919
Reactome:R-HSA-68918
Reactome:R-HSA-68917
Reactome:R-HSA-68916
Reactome:R-HSA-68849
Reactome:R-HSA-68826
Reactome:R-HSA-68688
Reactome:R-HSA-68615
Reactome:R-HSA-176973
Reactome:R-HSA-176318
Reactome:R-HSA-176298

ECO:0000304

author statement supported by traceable reference used in manual assertion













C

Seeded From UniProt

complete

involved_in

GO:0000082

G1/S transition of mitotic cell cycle

Reactome:R-HSA-69206

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0238

F

Seeded From UniProt

complete

involved_in

GO:0006260

DNA replication

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0235

P

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0539
UniProtKB-SubCell:SL-0191

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Varma, D et al. (2012) Recruitment of the human Cdt1 replication licensing protein by the loop domain of Hec1 is required for stable kinetochore-microtubule attachment. Nat. Cell Biol. 14 593-603 PubMed GONUTS page
  2. Ghosh, D et al. (2010) Defining the membrane proteome of NK cells. J Mass Spectrom 45 1-25 PubMed GONUTS page
  3. Siddiqui, K & Stillman, B (2007) ATP-dependent assembly of the human origin recognition complex. J. Biol. Chem. 282 32370-83 PubMed GONUTS page
  4. 4.0 4.1 4.2 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page