HUMAN:NELFA

Species (Taxon ID)	Homo sapiens (Human). (9606)
Gene Name(s)	NELFA (synonyms: WHSC2)
Protein Name(s)	Negative elongation factor A NELF-A Wolf-Hirschhorn syndrome candidate 2 protein
External Links
UniProt	Q9H3P2
EMBL	AF101434 AB044549 AF131751 AK126056 AL132868 CH471131 BC002764
RefSeq	NP_005654.3
UniGene	Hs.21771
ProteinModelPortal	Q9H3P2
BioGrid	113307
DIP	DIP-48478N
IntAct	Q9H3P2
MINT	MINT-3067399
STRING	9606.ENSP00000372335
PhosphoSite	Q9H3P2
DMDM	212276499
MaxQB	Q9H3P2
PaxDb	Q9H3P2
PRIDE	Q9H3P2
DNASU	7469
Ensembl	ENST00000382882 ENST00000411638 ENST00000542778
GeneID	7469
KEGG	hsa:7469
UCSC	uc003gek.3
CTD	7469
GeneCards	GC04M001985
HGNC	HGNC:12768
HPA	CAB009960 HPA039858 HPA043931
MIM	606026
neXtProt	NX_Q9H3P2
Orphanet	280
PharmGKB	PA37371
eggNOG	NOG10551
GeneTree	ENSGT00390000005342
HOGENOM	HOG000113765
HOVERGEN	HBG052595
InParanoid	Q9H3P2
KO	K15179
OrthoDB	EOG708VZQ
PhylomeDB	Q9H3P2
TreeFam	TF324956
Reactome	REACT_22107 REACT_22201 REACT_6143 REACT_6162 REACT_6244 REACT_6259 REACT_6261 REACT_6319 REACT_6344 REACT_6346 REACT_833 REACT_846
GeneWiki	WHSC2
GenomeRNAi	7469
NextBio	29260
PRO	PR:Q9H3P2
Proteomes	UP000005640
Bgee	Q9H3P2
CleanEx	HS_WHSC2
ExpressionAtlas	Q9H3P2
Genevestigator	Q9H3P2
GO	GO:0005737 GO:0032021 GO:0005654 GO:0005634 GO:0003682 GO:0010467 GO:0007275 GO:0034244 GO:0050434 GO:0006368 GO:0006366 GO:0016032
InterPro	IPR026305
PANTHER	PTHR13328

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Notes	Status
part_of	GO:0032021	NELF complex	PMID:12612062^[1]	ECO:0000314	direct assay evidence used in manual assertion		C	Seeded From UniProt	complete
involved_in	GO:0034244	negative regulation of transcription elongation from RNA polymerase II promoter	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0038872 MGI:MGI:1346098 PANTHER:PTN001000126	P	Seeded From UniProt	complete
part_of	GO:0032021	NELF complex	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0038872 PANTHER:PTN001000126 UniProtKB:Q9H3P2	C	Seeded From UniProt	complete
part_of	GO:0016604	nuclear body	GO_REF:0000052	ECO:0000314	direct assay evidence used in manual assertion		C	Seeded From UniProt	complete
part_of	GO:0005829	cytosol	GO_REF:0000052	ECO:0000314	direct assay evidence used in manual assertion		C	Seeded From UniProt	complete
part_of	GO:0005654	nucleoplasm	GO_REF:0000052	ECO:0000314	direct assay evidence used in manual assertion		C	Seeded From UniProt	complete
part_of	GO:0032021	NELF complex	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR026305	C	Seeded From UniProt	complete
involved_in	GO:0034244	negative regulation of transcription elongation from RNA polymerase II promoter	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR026305	P	Seeded From UniProt	complete
involved_in	GO:0007275	multicellular organism development	PMID:10409432^[3]	ECO:0000304	author statement supported by traceable reference used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0050434	positive regulation of viral transcription	Reactome:R-HSA-167246	ECO:0000304	author statement supported by traceable reference used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0006368	transcription elongation from RNA polymerase II promoter	Reactome:R-HSA-75955 Reactome:R-HSA-113418 Reactome:R-HSA-112382	ECO:0000304	author statement supported by traceable reference used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0006366	transcription by RNA polymerase II	Reactome:R-HSA-73857	ECO:0000304	author statement supported by traceable reference used in manual assertion		P	Seeded From UniProt	complete
part_of	GO:0005654	nucleoplasm	Reactome:R-HSA-6797616 Reactome:R-HSA-6797606 Reactome:R-HSA-170706 Reactome:R-HSA-170704 Reactome:R-HSA-113429 Reactome:R-HSA-113414 Reactome:R-HSA-113413 Reactome:R-HSA-113412 Reactome:R-HSA-113411 Reactome:R-HSA-113409 Reactome:R-HSA-113402 Reactome:R-HSA-112437 Reactome:R-HSA-112396 Reactome:R-HSA-112395 Reactome:R-HSA-112392 Reactome:R-HSA-112385 Reactome:R-HSA-112381 Reactome:R-HSA-112379	ECO:0000304	author statement supported by traceable reference used in manual assertion		C	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0539 UniProtKB-SubCell:SL-0191	C	Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ Narita, T et al. (2003) Human transcription elongation factor NELF: identification of novel subunits and reconstitution of the functionally active complex. Mol. Cell. Biol. 23 1863-73 PubMed GONUTS page
↑ ^2.0 ^2.1 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
↑ Wright, TJ et al. (1999) Comparative analysis of a novel gene from the Wolf-Hirschhorn/Pitt-Rogers-Danks syndrome critical region. Genomics 59 203-12 PubMed GONUTS page

[PMID:12612062-1] Narita, T et al. (2003) Human transcription elongation factor NELF: identification of novel subunits and reconstitution of the functionally active complex. Mol. Cell. Biol. 23 1863-73 PubMed GONUTS page

[PMID:21873635-2] 2.0 ^2.1 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:10409432-3] Wright, TJ et al. (1999) Comparative analysis of a novel gene from the Wolf-Hirschhorn/Pitt-Rogers-Danks syndrome critical region. Genomics 59 203-12 PubMed GONUTS page

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HUMAN:NELFA

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