HUMAN:NEK3

Species (Taxon ID)	Homo sapiens (Human). (9606)
Gene Name(s)	NEK3
Protein Name(s)	Serine/threonine-protein kinase Nek3 HSPK 36 Never in mitosis A-related kinase 3 NimA-related protein kinase 3
External Links
UniProt	P51956
EMBL	AB072828 AK290259 AL139082 CH471075 BC019916 Z29067 Z25434
CCDS	CCDS73576.1
PIR	I38224
RefSeq	NP_001139571.1 NP_002489.1 NP_689933.1
UniGene	Hs.409989
ProteinModelPortal	P51956
SMR	P51956
BioGrid	110827
IntAct	P51956
STRING	9606.ENSP00000383210
BindingDB	P51956
ChEMBL	CHEMBL5679
GuidetoPHARMACOLOGY	2118
PhosphoSite	P51956
DMDM	20178297
MaxQB	P51956
PaxDb	P51956
PRIDE	P51956
DNASU	4752
Ensembl	ENST00000610828 ENST00000611833 ENST00000618534
GeneID	4752
KEGG	hsa:4752
UCSC	uc001vgi.3 uc010tgy.2
CTD	4752
GeneCards	GC13M052706
HGNC	HGNC:7746
HPA	HPA019062 HPA043230
MIM	604044
neXtProt	NX_P51956
PharmGKB	PA31547
eggNOG	COG0515
GeneTree	ENSGT00760000118997
HOGENOM	HOG000261617
HOVERGEN	HBG003063
InParanoid	P51956
KO	K08857
OrthoDB	EOG7D59P5
PhylomeDB	P51956
TreeFam	TF106472
BRENDA	2.7.11.1
SignaLink	P51956
GeneWiki	NEK3
GenomeRNAi	4752
NextBio	18314
PRO	PR:P51956
Proteomes	UP000005640
Bgee	P51956
CleanEx	HS_NEK3
ExpressionAtlas	P51956
Genevestigator	P51956
GO	GO:0030424 GO:0005737 GO:0005634 GO:0005524 GO:0046872 GO:0004674 GO:0007067 GO:0006468
InterPro	IPR011009 IPR000719 IPR017441 IPR002290 IPR008271
Pfam	PF00069
SMART	SM00220
SUPFAM	SSF56112
PROSITE	PS00107 PS50011 PS00108

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
involved_in	GO:0000278	mitotic cell cycle	PMID:7522034	ECO:0000303	author statement without traceable support used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0006468	protein phosphorylation	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q9R0A5	P		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:7522034	ECO:0000303	author statement without traceable support used in manual assertion		C		Seeded From UniProt	complete
enables	GO:0004674	protein serine/threonine kinase activity	PMID:7522034	ECO:0000303	author statement without traceable support used in manual assertion		F		Seeded From UniProt	complete
involved_in	GO:0090043	regulation of tubulin deacetylation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9R0A5 ensembl:ENSMUSP00000106358	P		Seeded From UniProt	complete
involved_in	GO:0048812	neuron projection morphogenesis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9R0A5 ensembl:ENSMUSP00000106358	P		Seeded From UniProt	complete
involved_in	GO:0030010	establishment of cell polarity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9R0A5 ensembl:ENSMUSP00000106358	P		Seeded From UniProt	complete
involved_in	GO:0006468	protein phosphorylation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9R0A5 ensembl:ENSMUSP00000106358	P		Seeded From UniProt	complete
enables	GO:0004672	protein kinase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000719 InterPro:IPR008271	F		Seeded From UniProt	complete
enables	GO:0005524	ATP binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000719 InterPro:IPR017441	F		Seeded From UniProt	complete
involved_in	GO:0006468	protein phosphorylation	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000719 InterPro:IPR008271	P		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0963 UniProtKB-SubCell:SL-0086	C		Seeded From UniProt	complete
enables	GO:0016301	kinase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0418	F		Seeded From UniProt	complete
involved_in	GO:0007049	cell cycle	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0131	P		Seeded From UniProt	complete
enables	GO:0005524	ATP binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0067	F		Seeded From UniProt	complete
enables	GO:0004674	protein serine/threonine kinase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0723	F		Seeded From UniProt	complete
involved_in	GO:0016310	phosphorylation	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0418	P		Seeded From UniProt	complete
enables	GO:0016740	transferase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0808	F		Seeded From UniProt	complete
involved_in	GO:0051301	cell division	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0132	P		Seeded From UniProt	complete
part_of	GO:0042995	cell projection	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0966	C		Seeded From UniProt	complete
enables	GO:0046872	metal ion binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0479	F		Seeded From UniProt	complete
enables	GO:0000166	nucleotide binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0547	F		Seeded From UniProt	complete
part_of	GO:0030424	axon	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0279	C		Seeded From UniProt	complete
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References

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