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HUMAN:MUC5A
Contents
| Species (Taxon ID) | Homo sapiens (Human). (9606) | |
| Gene Name(s) | MUC5AC (synonyms: MUC5) | |
| Protein Name(s) | Mucin-5AC
MUC-5AC Gastric mucin Lewis B blood group antigen LeB Major airway glycoprotein Mucin-5 subtype AC, tracheobronchial Tracheobronchial mucin TBM | |
| External Links | ||
| UniProt | P98088 | |
| EMBL | AJ298317 AJ298318 AJ298319 AF015521 X81649 AJ001402 AJ001403 U06711 Z48314 BC033831 AL833060 | |
| PIR | A33811 JE0095 | |
| UniGene | Hs.534332 Hs.558950 Hs.721515 | |
| ProteinModelPortal | P98088 | |
| SMR | P98088 | |
| IntAct | P98088 | |
| MEROPS | I08.951 | |
| UniCarbKB | P98088 | |
| DMDM | 160370004 | |
| MaxQB | P98088 | |
| PRIDE | P98088 | |
| GeneCards | GC11P001151 | |
| H-InvDB | HIX0201650 | |
| HGNC | HGNC:7515 | |
| HPA | CAB002774 CAB009395 HPA040615 | |
| MIM | 158373 | |
| neXtProt | NX_P98088 | |
| InParanoid | P98088 | |
| Reactome | REACT_115606 REACT_115835 | |
| NextBio | 125477 | |
| PRO | PR:P98088 | |
| Proteomes | UP000005640 | |
| Genevestigator | P98088 | |
| GO | GO:0070062 GO:0043205 GO:0005796 GO:0005201 GO:0044267 GO:0043206 GO:0016266 GO:0043687 | |
| InterPro | IPR006207 IPR002919 IPR014853 IPR001007 IPR001846 IPR025155 | |
| Pfam | PF08742 PF13330 PF01826 PF00094 | |
| SMART | SM00832 SM00041 SM00214 SM00216 | |
| SUPFAM | SSF57567 | |
| PROSITE | PS01185 PS01225 PS01208 PS50184 PS51233 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
involved_in |
GO:0048015 |
phosphatidylinositol-mediated signaling |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
occurs_in:(CL:0002368) |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
part_of:(CL:0002368) |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005615 |
extracellular space |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
part_of:(CL:0002368) |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0070062 |
extracellular exosome |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
C |
part_of:(UBERON:0001831) |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0070701 |
mucus layer |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005201 |
extracellular matrix structural constituent |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0016266 |
O-glycan processing |
Reactome:R-HSA-913709 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005886 |
plasma membrane |
Reactome:R-HSA-8858500 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005796 |
Golgi lumen |
Reactome:R-HSA-981814 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
|
C |
Seeded From UniProt |
complete | |
|
involved_in |
GO:0002223 |
stimulatory C-type lectin receptor signaling pathway |
Reactome:R-HSA-5621481 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005576 |
extracellular region |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 Li, Q et al. (2015) Ezrin/Exocyst complex regulates mucin 5AC secretion induced by neutrophil elastase in human airway epithelial cells. Cell. Physiol. Biochem. 35 326-38 PubMed GONUTS page
- ↑ Gonzalez-Begne, M et al. (2009) Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT). J. Proteome Res. 8 1304-14 PubMed GONUTS page
- ↑ Sheehan, JK et al. (2004) Identification of molecular intermediates in the assembly pathway of the MUC5AC mucin. J. Biol. Chem. 279 15698-705 PubMed GONUTS page
- ↑ Meezaman, D et al. (1994) Cloning and analysis of cDNA encoding a major airway glycoprotein, human tracheobronchial mucin (MUC5). J. Biol. Chem. 269 12932-9 PubMed GONUTS page
