HUMAN:MSH5

Species (Taxon ID)	Homo sapiens (Human). (9606)
Gene Name(s)	MSH5
Protein Name(s)	MutS protein homolog 5 hMSH5
External Links
UniProt	O43196
EMBL	AF048986 AF048991 AF048988 AF048989 AF048990 AF034759 AF070071 AF070079 AF070072 AF070073 AF070074 AF070075 AF070076 AF070077 AF070078 BT007200 AY943816 BA000025 AF129756 AF134726 AL662834 AL662834 AL662899 AL662899 CR936239 CR925765 CR936239 CR925765 CR759787 CR759787 CR925765 CR936239 CR925765 CR936239 CH471081 CH471081 BC001358 BC002498 BC041031
CCDS	CCDS34409.2 CCDS34410.1 CCDS4720.1
RefSeq	NP_002432.1 NP_079535.4 NP_751897.1 NP_751898.1
UniGene	Hs.647011
ProteinModelPortal	O43196
SMR	O43196
BioGrid	110576
IntAct	O43196
MINT	MINT-2999175
STRING	9606.ENSP00000364894
PhosphoSite	O43196
MaxQB	O43196
PaxDb	O43196
PRIDE	O43196
DNASU	4439
Ensembl	ENST00000375703 ENST00000375740 ENST00000375750 ENST00000375755 ENST00000412070 ENST00000416549 ENST00000419269 ENST00000420731 ENST00000427735 ENST00000435700 ENST00000436091 ENST00000436192 ENST00000441395 ENST00000441401 ENST00000448617 ENST00000456839 ENST00000457742
GeneID	4439
KEGG	hsa:4439
UCSC	uc003nwu.2 uc003nwv.2 uc003nwx.2
CTD	4439
GeneCards	GC06P031707 GC06Pj31696 GC06Pk31690 GC06Pl31747 GC06Pm31785
H-InvDB	HIX0165917 HIX0166738 HIX0167237 HIX0167372
HGNC	HGNC:7328
MIM	603382
neXtProt	NX_O43196
PharmGKB	PA31136
eggNOG	COG0249
GeneTree	ENSGT00550000074977
HOVERGEN	HBG001449
InParanoid	O43196
KO	K08741
OMA	VESHAFM
PhylomeDB	O43196
TreeFam	TF314549
Reactome	REACT_27271
ChiTaRS	MSH5
GeneWiki	MSH5
GenomeRNAi	4439
NextBio	17301
PRO	PR:O43196
Proteomes	UP000005640 UP000005640
Bgee	O43196
CleanEx	HS_MSH5
ExpressionAtlas	O43196
Genevestigator	O43196
GO	GO:0000795 GO:0005524 GO:0008094 GO:0030983 GO:0006200 GO:0051026 GO:0045143 GO:0006298 GO:0007131
Gene3D	3.40.50.300
InterPro	IPR000432 IPR007861 IPR007696 IPR027417
Pfam	PF05192 PF05190 PF00488
SMART	SM00534 SM00533
SUPFAM	SSF48334 SSF52540
PROSITE	PS00486

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
involved_in	GO:0051026	chiasma assembly		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000145508 TAIR:locus:2092404 UniProtKB:Q6L4V0 WB:WBGene00003421	P		Seeded From UniProt	complete
involved_in	GO:0045143	homologous chromosome segregation		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000145508 UniProtKB:Q6L4V0 WB:WBGene00003421	P		Seeded From UniProt	complete
part_of	GO:0032300	mismatch repair complex		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	EcoGene:EG10625 PANTHER:PTN002260779	C		Seeded From UniProt	complete
contributes_to	GO:0032143	single thymine insertion binding		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN002260779 UniProtKB:P43246 UniProtKB:P52701	F		Seeded From UniProt	complete
contributes_to	GO:0032137	guanine/thymine mispair binding		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:101816 MGI:MGI:1343961 PANTHER:PTN002260779 SGD:S000001162 SGD:S000002504 SGD:S000005450 UniProtKB:P43246 UniProtKB:P52701	F		Seeded From UniProt	complete
enables	GO:0008094	DNA-dependent ATPase activity		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN002260779 SGD:S000001162	F		Seeded From UniProt	complete
involved_in	GO:0007131	reciprocal meiotic recombination		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000145508 SGD:S000002313 TAIR:locus:2092404 UniProtKB:Q6L4V0 WB:WBGene00003421	P		Seeded From UniProt	complete
involved_in	GO:0006298	mismatch repair		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	EcoGene:EG10625 FB:FBgn0015546 MGI:MGI:101816 MGI:MGI:109519 MGI:MGI:1343961 PANTHER:PTN000145505 PomBase:SPBC19G7.01c PomBase:SPCC285.16c SGD:S000000688 SGD:S000001162 SGD:S000002504 SGD:S000005450 TAIR:locus:2095097 UniProtKB:P20585 UniProtKB:P43246 UniProtKB:P52701 WB:WBGene00003418 WB:WBGene00003422	P		Seeded From UniProt	complete
enables	GO:0005524	ATP binding		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	EcoGene:EG10625 PANTHER:PTN002260779 SGD:S000002504 SGD:S000005450 UniProtKB:P43246 UniProtKB:P52701	F		Seeded From UniProt	complete
enables	GO:0005524	ATP binding		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	EcoGene:EG10625 PANTHER:PTN002260779 SGD:S000002504 SGD:S000005450	F		Seeded From UniProt	complete
enables	GO:0003684	damaged DNA binding		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:101816 MGI:MGI:109519 MGI:MGI:1343961 PANTHER:PTN002260779 TAIR:locus:2095097 TAIR:locus:2131829 UniProtKB:O04716	F		Seeded From UniProt	complete
enables	GO:0005524	ATP binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000432 InterPro:IPR007696 InterPro:IPR007861 InterPro:IPR011184	F		Seeded From UniProt	complete
involved_in	GO:0006298	mismatch repair	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000432 InterPro:IPR007696 InterPro:IPR007861 InterPro:IPR011184	P		Seeded From UniProt	complete
enables	GO:0030983	mismatched DNA binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000432 InterPro:IPR007696 InterPro:IPR007861 InterPro:IPR011184	F		Seeded From UniProt	complete
involved_in	GO:0006974	cellular response to DNA damage stimulus	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0227	P		Seeded From UniProt	complete
involved_in	GO:0051321	meiotic cell cycle	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0469	P		Seeded From UniProt	complete
enables	GO:0003677	DNA binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0238	F		Seeded From UniProt	complete
enables	GO:0005524	ATP binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0067	F		Seeded From UniProt	complete
involved_in	GO:0006281	DNA repair	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0234	P		Seeded From UniProt	complete
enables	GO:0000166	nucleotide binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0547	F		Seeded From UniProt	complete
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References

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