GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.
HUMAN:MACD1
Contents
Species (Taxon ID) | Homo sapiens (Human). (9606) | |
Gene Name(s) | MACROD1 (synonyms: LRP16) | |
Protein Name(s) | O-acetyl-ADP-ribose deacetylase MACROD1
MACRO domain-containing protein 1 Protein LRP16 [Protein ADP-ribosylglutamate] hydrolase | |
External Links | ||
UniProt | Q9BQ69 | |
EMBL | AF202922 BC000270 BC003188 BC007297 BC008316 | |
CCDS | CCDS8056.1 | |
RefSeq | NP_054786.2 | |
UniGene | Hs.602898 | |
PDB | 2X47 | |
PDBsum | 2X47 | |
ProteinModelPortal | Q9BQ69 | |
SMR | Q9BQ69 | |
BioGrid | 118813 | |
IntAct | Q9BQ69 | |
STRING | 9606.ENSP00000255681 | |
PhosphoSite | Q9BQ69 | |
DMDM | 32129719 | |
MaxQB | Q9BQ69 | |
PaxDb | Q9BQ69 | |
PeptideAtlas | Q9BQ69 | |
PRIDE | Q9BQ69 | |
Ensembl | ENST00000255681 | |
GeneID | 28992 | |
KEGG | hsa:28992 | |
UCSC | uc001nyh.3 | |
CTD | 28992 | |
GeneCards | GC11M063767 | |
HGNC | HGNC:29598 | |
HPA | HPA041031 | |
MIM | 610400 | |
neXtProt | NX_Q9BQ69 | |
PharmGKB | PA162394816 | |
eggNOG | COG2110 | |
GeneTree | ENSGT00520000055566 | |
HOGENOM | HOG000086960 | |
HOVERGEN | HBG052356 | |
InParanoid | Q9BQ69 | |
OMA | KITCGYR | |
OrthoDB | EOG7D2FFN | |
PhylomeDB | Q9BQ69 | |
TreeFam | TF341440 | |
ChiTaRS | MACROD1 | |
EvolutionaryTrace | Q9BQ69 | |
GenomeRNAi | 28992 | |
NextBio | 51921 | |
PRO | PR:Q9BQ69 | |
Proteomes | UP000005640 | |
Bgee | Q9BQ69 | |
CleanEx | HS_MACROD1 | |
Genevestigator | Q9BQ69 | |
GO | GO:0005739 GO:0005634 GO:0019213 GO:0016798 GO:0006974 GO:0051725 GO:0042278 | |
InterPro | IPR002589 | |
Pfam | PF01661 | |
SMART | SM00506 | |
PROSITE | PS51154 |
Annotations
Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
---|---|---|---|---|---|---|---|---|---|---|
involved_in |
GO:0140291 |
peptidyl-glutamate ADP-deribosylation |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0140293 |
ADP-ribosylglutamate hydrolase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0051725 |
protein de-ADP-ribosylation |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0042278 |
purine nucleoside metabolic process |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0019213 |
deacetylase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0016798 |
hydrolase activity, acting on glycosyl bonds |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0006974 |
cellular response to DNA damage stimulus |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0005634 |
nucleus |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005654 |
nucleoplasm |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005634 |
nucleus |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0006974 |
cellular response to DNA damage stimulus |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0016787 |
hydrolase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Rosenthal, F et al. (2013) Macrodomain-containing proteins are new mono-ADP-ribosylhydrolases. Nat. Struct. Mol. Biol. 20 502-7 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 Jankevicius, G et al. (2013) A family of macrodomain proteins reverses cellular mono-ADP-ribosylation. Nat. Struct. Mol. Biol. 20 508-14 PubMed GONUTS page
- ↑ 3.0 3.1 Chen, D et al. (2011) Identification of macrodomain proteins as novel O-acetyl-ADP-ribose deacetylases. J. Biol. Chem. 286 13261-71 PubMed GONUTS page