HUMAN:KCMA1

Species (Taxon ID)	Homo sapiens (Human). (9606)
Gene Name(s)	KCNMA1 (synonyms: KCNMA, SLO)
Protein Name(s)	Calcium-activated potassium channel subunit alpha-1 BK channel BKCA alpha Calcium-activated potassium channel, subfamily M subunit alpha-1 K(VCA)alpha KCa1.1 Maxi K channel MaxiK Slo-alpha Slo1 Slowpoke homolog Slo homolog hSlo
External Links
UniProt	Q12791
EMBL	U13913 U23767 AL157833 AL731560 AL731556 AL627447 AC021032 AC011439 AL157833 AC011439 AC021032 AL627447 AL731556 AL731560 AL627447 AL731560 AL731556 AC021032 AC011439 AL157833 AL627447 AC011439 AC021032 AL157833 AL731556 AL731560 AL731556 AC011439 AL157833 AC021032 AL731560 AL627447 AL731556 AC011439 AC021032 AL157833 AL627447 AL731560 AL731560 AL157833 AL731556 AC021032 AC011439 AL627447 AL731560 AC011439 AC021032 AL157833 AL627447 AL731556 AC067745 AL607069 AL731575 CH471083 BC062659 BC137115 BC137137 U11717 AY040849 AB113575 AB113382 U02632 U09384 AF025999 U11058 AF118141
CCDS	CCDS60569.1 CCDS60571.1 CCDS7352.1
PIR	I38596 S62904
RefSeq	NP_001014797.1 NP_001154824.1 NP_001154825.1 NP_001258447.1 NP_001258451.1 NP_002238.2
UniGene	Hs.144795
PDB	2K44 3MT5 3NAF
PDBsum	2K44 3MT5 3NAF
ProteinModelPortal	Q12791
SMR	Q12791
BioGrid	109979
DIP	DIP-29729N
IntAct	Q12791
MINT	MINT-4825316
BindingDB	Q12791
ChEMBL	CHEMBL3038495
DrugBank	DB00436 DB00356 DB01003 DB01119 DB01159 DB00999 DB00774 DB01110 DB00721
GuidetoPHARMACOLOGY	380
PhosphoSite	Q12791
DMDM	46396283
MaxQB	Q12791
PaxDb	Q12791
PRIDE	Q12791
Ensembl	ENST00000286627 ENST00000286628 ENST00000480683
GeneID	3778
KEGG	hsa:3778
UCSC	uc001jxj.2 uc001jxk.1 uc001jxn.3 uc001jxo.3 uc001jxs.4 uc009xrt.1
CTD	3778
GeneCards	GC10M078629
HGNC	HGNC:6284
HPA	HPA054648
MIM	600150 609446
neXtProt	NX_Q12791
Orphanet	79137
PharmGKB	PA220
eggNOG	COG1226
GeneTree	ENSGT00530000063026
HOVERGEN	HBG052222
InParanoid	Q12791
KO	K04936
PhylomeDB	Q12791
TreeFam	TF314283
Reactome	REACT_23767 REACT_75896
ChiTaRS	KCNMA1
EvolutionaryTrace	Q12791
GenomeRNAi	3778
NextBio	14823
PRO	PR:Q12791
Proteomes	UP000005640
Bgee	Q12791
ExpressionAtlas	Q12791
Genevestigator	Q12791
GO	GO:0016324 GO:0005901 GO:0070062 GO:0016021 GO:0005886 GO:0008076 GO:0003779 GO:0015269 GO:0060072 GO:0046872 GO:0005249 GO:0007596 GO:0030007 GO:0060073 GO:0045794 GO:0043065 GO:0071805 GO:0006813 GO:0042391 GO:0051592 GO:0034465 GO:0001666 GO:0006970 GO:0060083 GO:0007268
Gene3D	3.40.50.720
InterPro	IPR005821 IPR003091 IPR003929 IPR016040 IPR003148
Pfam	PF03493 PF00520 PF02254
PRINTS	PR01449 PR00169

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
enables	GO:0060072	large conductance calcium-activated potassium channel activity	PMID:15703204^[1]	ECO:0000315	mutant phenotype evidence used in manual assertion		F		Seeded From UniProt	complete
part_of	GO:0005901	caveola	PMID:15703204^[1]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(UBERON:0001296) part_of:(CL:0000192)	Seeded From UniProt	complete
enables	GO:0003779	actin binding	PMID:15703204^[1]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
	GO:0015269	calcium-activated potassium channel activity	PMCID: PMC2727533	ECO:0000315			F		Figure 4. Differential BKCa channel activity measured by membrane potential in breast cancer cell lines.	complete
involved_in	GO:0060083	smooth muscle contraction involved in micturition	PMID:11641143^[2]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0060073	micturition	PMID:11641143^[2]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0060072	large conductance calcium-activated potassium channel activity	PMID:7993625^[3]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
involved_in	GO:0051592	response to calcium ion	PMID:18458941^[4]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0051592	response to calcium ion	PMID:12388065^[5]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0045794	negative regulation of cell volume	PMID:12388065^[5]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0043065	positive regulation of apoptotic process	PMID:11245614^[6]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0042391	regulation of membrane potential	PMID:7993625^[3]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0042391	regulation of membrane potential	PMID:7877450^[7]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0034465	response to carbon monoxide	PMID:18180950^[8]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0034465	response to carbon monoxide	PMID:15528406^[9]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0030007	cellular potassium ion homeostasis	PMID:11245614^[6]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0016324	apical plasma membrane	PMID:10840032^[10]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0016021	integral component of membrane	PMID:7877450^[7]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0016021	integral component of membrane	PMID:7573516^[11]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
enables	GO:0015269	calcium-activated potassium channel activity	PMID:11245614^[6]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0015269	calcium-activated potassium channel activity	PMID:7877450^[7]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0015269	calcium-activated potassium channel activity	PMID:7573516^[11]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0015269	calcium-activated potassium channel activity	PMID:18458941^[4]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0015269	calcium-activated potassium channel activity	PMID:17706472^[12]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
part_of	GO:0008076	voltage-gated potassium channel complex	PMID:7877450^[7]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0008076	voltage-gated potassium channel complex	PMID:7573516^[11]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0006970	response to osmotic stress	PMID:10840032^[10]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0006970	response to osmotic stress	PMID:12388065^[5]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0006813	potassium ion transport	PMID:11245614^[6]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0006813	potassium ion transport	PMID:7877450^[7]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0006813	potassium ion transport	PMID:7573516^[11]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0006813	potassium ion transport	PMID:12388065^[5]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0006813	potassium ion transport	PMID:18458941^[4]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0006813	potassium ion transport	PMID:17706472^[12]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0005249	voltage-gated potassium channel activity	PMID:7877450^[7]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0005249	voltage-gated potassium channel activity	PMID:12388065^[5]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
involved_in	GO:0001666	response to hypoxia	PMID:15528406^[9]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0060087	relaxation of vascular smooth muscle	PMID:21873635^[13]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:99923 PANTHER:PTN000002894 UniProtKB:O18866	P		Seeded From UniProt	complete
enables	GO:0060072	large conductance calcium-activated potassium channel activity	PMID:21873635^[13]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:99923 PANTHER:PTN002224803 RGD:620715 UniProtKB:Q12791	F		Seeded From UniProt	complete
part_of	GO:0045211	postsynaptic membrane	PMID:21873635^[13]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:99923 PANTHER:PTN000002875	C		Seeded From UniProt	complete
involved_in	GO:0042391	regulation of membrane potential	PMID:21873635^[13]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:99923 PANTHER:PTN000002872 UniProtKB:Q12791	P		Seeded From UniProt	complete
part_of	GO:0016021	integral component of membrane	PMID:21873635^[13]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:99923 PANTHER:PTN000002872 RGD:621106 UniProtKB:Q12791	C		Seeded From UniProt	complete
enables	GO:0015271	outward rectifier potassium channel activity	PMID:21873635^[13]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000002872 WB:WBGene00004831	F		Seeded From UniProt	complete
enables	GO:0015269	calcium-activated potassium channel activity	PMID:21873635^[13]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0003429 MGI:MGI:99923 PANTHER:PTN002224803 RGD:620715 UniProtKB:Q12791 UniProtKB:Q28204 WB:WBGene00004830	F		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	PMID:21873635^[13]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:99923 PANTHER:PTN000002872 RGD:620715	C		Seeded From UniProt	complete
enables	GO:0005216	ion channel activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR005821	F		Seeded From UniProt	complete
enables	GO:0005249	voltage-gated potassium channel activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR028325	F		Seeded From UniProt	complete
involved_in	GO:0006811	ion transport	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR005821	P		Seeded From UniProt	complete
involved_in	GO:0006813	potassium ion transport	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR003929 InterPro:IPR028325	P		Seeded From UniProt	complete
part_of	GO:0008076	voltage-gated potassium channel complex	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR028325	C		Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR003929 InterPro:IPR005821	C		Seeded From UniProt	complete
involved_in	GO:0055085	transmembrane transport	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR005821	P		Seeded From UniProt	complete
enables	GO:0060072	large conductance calcium-activated potassium channel activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR024939	F		Seeded From UniProt	complete
enables	GO:0060072	large conductance calcium-activated potassium channel activity	PMID:7993625^[3]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0015269	calcium-activated potassium channel activity	PMID:7993625^[3]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
part_of	GO:0008076	voltage-gated potassium channel complex	PMID:7993625^[3]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0006813	potassium ion transport	PMID:7993625^[3]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0005249	voltage-gated potassium channel activity	PMID:7993625^[3]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
involved_in	GO:0071805	potassium ion transmembrane transport	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0005249	P		Seeded From UniProt	complete
enables	GO:0042802	identical protein binding	PMID:20574420^[14]	ECO:0000353	physical interaction evidence used in manual assertion	UniProtKB:Q12791-5	F		Seeded From UniProt	complete
part_of	GO:0016021	integral component of membrane	PMID:11880513^[15]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
enables	GO:0015269	calcium-activated potassium channel activity	PMID:11880513^[15]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0005249	voltage-gated potassium channel activity	PMID:11880513^[15]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
involved_in	GO:0071805	potassium ion transmembrane transport	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0005249	P		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	Reactome:R-HSA-1296037	ECO:0000304	author statement supported by traceable reference used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0016021	integral component of membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0812	C		Seeded From UniProt	complete
involved_in	GO:0006813	potassium ion transport	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0633	P		Seeded From UniProt	complete
enables	GO:0005267	potassium channel activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0631	F		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-1003 UniProtKB-SubCell:SL-0039	C		Seeded From UniProt	complete
enables	GO:0005244	voltage-gated ion channel activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0851	F		Seeded From UniProt	complete
involved_in	GO:0006811	ion transport	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0406	P		Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0472	C		Seeded From UniProt	complete
involved_in	GO:0034765	regulation of ion transmembrane transport	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0851	P		Seeded From UniProt	complete
enables	GO:0046872	metal ion binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0479	F		Seeded From UniProt	complete
involved_in	GO:0071805	potassium ion transmembrane transport	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0631	P		Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 ^1.2 Brainard, AM et al. (2005) Maxi-K channels localize to caveolae in human myometrium: a role for an actin-channel-caveolin complex in the regulation of myometrial smooth muscle K+ current. Am. J. Physiol., Cell Physiol. 289 C49-57 PubMed GONUTS page
↑ ^2.0 ^2.1 Christ, GJ et al. (2001) Bladder injection of "naked" hSlo/pcDNA3 ameliorates detrusor hyperactivity in obstructed rats in vivo. Am. J. Physiol. Regul. Integr. Comp. Physiol. 281 R1699-709 PubMed GONUTS page
↑ ^3.0 ^3.1 ^3.2 ^3.3 ^3.4 ^3.5 ^3.6 Tseng-Crank, J et al. (1994) Cloning, expression, and distribution of functionally distinct Ca(2+)-activated K+ channel isoforms from human brain. Neuron 13 1315-30 PubMed GONUTS page
↑ ^4.0 ^4.1 ^4.2 Fernández-Fernández, JM et al. (2008) Functional coupling of TRPV4 cationic channel and large conductance, calcium-dependent potassium channel in human bronchial epithelial cell lines. Pflugers Arch. 457 149-59 PubMed GONUTS page
↑ ^5.0 ^5.1 ^5.2 ^5.3 ^5.4 Fernández-Fernández, JM et al. (2002) Maxi K+ channel mediates regulatory volume decrease response in a human bronchial epithelial cell line. Am. J. Physiol., Cell Physiol. 283 C1705-14 PubMed GONUTS page
↑ ^6.0 ^6.1 ^6.2 ^6.3 Krick, S et al. (2001) Activation of K+ channels induces apoptosis in vascular smooth muscle cells. Am. J. Physiol., Cell Physiol. 280 C970-9 PubMed GONUTS page
↑ ^7.0 ^7.1 ^7.2 ^7.3 ^7.4 ^7.5 Dworetzky, SI et al. (1994) Cloning and expression of a human large-conductance calcium-activated potassium channel. Brain Res. Mol. Brain Res. 27 189-93 PubMed GONUTS page
↑ Williams, SE et al. (2008) A structural motif in the C-terminal tail of slo1 confers carbon monoxide sensitivity to human BK Ca channels. Pflugers Arch. 456 561-72 PubMed GONUTS page
↑ ^9.0 ^9.1 Williams, SE et al. (2004) Hemoxygenase-2 is an oxygen sensor for a calcium-sensitive potassium channel. Science 306 2093-7 PubMed GONUTS page
↑ ^10.0 ^10.1 Allard, B et al. (2000) Characterization and gene expression of high conductance calcium-activated potassium channels displaying mechanosensitivity in human odontoblasts. J. Biol. Chem. 275 25556-61 PubMed GONUTS page
↑ ^11.0 ^11.1 ^11.2 ^11.3 McCobb, DP et al. (1995) A human calcium-activated potassium channel gene expressed in vascular smooth muscle. Am. J. Physiol. 269 H767-77 PubMed GONUTS page
↑ ^12.0 ^12.1 Dalziel, JE et al. (2007) Expression of human BK ion channels in Sf9 cells, their purification using metal affinity chromatography, and functional reconstitution into planar lipid bilayers. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 857 315-21 PubMed GONUTS page
↑ ^13.0 ^13.1 ^13.2 ^13.3 ^13.4 ^13.5 ^13.6 ^13.7 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
↑ Wu, Y et al. (2010) Structure of the gating ring from the human large-conductance Ca(2+)-gated K(+) channel. Nature 466 393-7 PubMed GONUTS page
↑ ^15.0 ^15.1 ^15.2 Liu, X et al. (2002) Cloning and characterization of glioma BK, a novel BK channel isoform highly expressed in human glioma cells. J. Neurosci. 22 1840-9 PubMed GONUTS page

[PMID:15703204-1] 1.0 ^1.1 ^1.2 Brainard, AM et al. (2005) Maxi-K channels localize to caveolae in human myometrium: a role for an actin-channel-caveolin complex in the regulation of myometrial smooth muscle K+ current. Am. J. Physiol., Cell Physiol. 289 C49-57 PubMed GONUTS page

[PMID:11641143-2] 2.0 ^2.1 Christ, GJ et al. (2001) Bladder injection of "naked" hSlo/pcDNA3 ameliorates detrusor hyperactivity in obstructed rats in vivo. Am. J. Physiol. Regul. Integr. Comp. Physiol. 281 R1699-709 PubMed GONUTS page

[PMID:7993625-3] 3.0 ^3.1 ^3.2 ^3.3 ^3.4 ^3.5 ^3.6 Tseng-Crank, J et al. (1994) Cloning, expression, and distribution of functionally distinct Ca(2+)-activated K+ channel isoforms from human brain. Neuron 13 1315-30 PubMed GONUTS page

[PMID:18458941-4] 4.0 ^4.1 ^4.2 Fernández-Fernández, JM et al. (2008) Functional coupling of TRPV4 cationic channel and large conductance, calcium-dependent potassium channel in human bronchial epithelial cell lines. Pflugers Arch. 457 149-59 PubMed GONUTS page

[PMID:12388065-5] 5.0 ^5.1 ^5.2 ^5.3 ^5.4 Fernández-Fernández, JM et al. (2002) Maxi K+ channel mediates regulatory volume decrease response in a human bronchial epithelial cell line. Am. J. Physiol., Cell Physiol. 283 C1705-14 PubMed GONUTS page

[PMID:11245614-6] 6.0 ^6.1 ^6.2 ^6.3 Krick, S et al. (2001) Activation of K+ channels induces apoptosis in vascular smooth muscle cells. Am. J. Physiol., Cell Physiol. 280 C970-9 PubMed GONUTS page

[PMID:7877450-7] 7.0 ^7.1 ^7.2 ^7.3 ^7.4 ^7.5 Dworetzky, SI et al. (1994) Cloning and expression of a human large-conductance calcium-activated potassium channel. Brain Res. Mol. Brain Res. 27 189-93 PubMed GONUTS page

[PMID:18180950-8] Williams, SE et al. (2008) A structural motif in the C-terminal tail of slo1 confers carbon monoxide sensitivity to human BK Ca channels. Pflugers Arch. 456 561-72 PubMed GONUTS page

[PMID:15528406-9] 9.0 ^9.1 Williams, SE et al. (2004) Hemoxygenase-2 is an oxygen sensor for a calcium-sensitive potassium channel. Science 306 2093-7 PubMed GONUTS page

[PMID:10840032-10] 10.0 ^10.1 Allard, B et al. (2000) Characterization and gene expression of high conductance calcium-activated potassium channels displaying mechanosensitivity in human odontoblasts. J. Biol. Chem. 275 25556-61 PubMed GONUTS page

[PMID:7573516-11] 11.0 ^11.1 ^11.2 ^11.3 McCobb, DP et al. (1995) A human calcium-activated potassium channel gene expressed in vascular smooth muscle. Am. J. Physiol. 269 H767-77 PubMed GONUTS page

[PMID:17706472-12] 12.0 ^12.1 Dalziel, JE et al. (2007) Expression of human BK ion channels in Sf9 cells, their purification using metal affinity chromatography, and functional reconstitution into planar lipid bilayers. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 857 315-21 PubMed GONUTS page

[PMID:21873635-13] 13.0 ^13.1 ^13.2 ^13.3 ^13.4 ^13.5 ^13.6 ^13.7 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:20574420-14] Wu, Y et al. (2010) Structure of the gating ring from the human large-conductance Ca(2+)-gated K(+) channel. Nature 466 393-7 PubMed GONUTS page

[PMID:11880513-15] 15.0 ^15.1 ^15.2 Liu, X et al. (2002) Cloning and characterization of glioma BK, a novel BK channel isoform highly expressed in human glioma cells. J. Neurosci. 22 1840-9 PubMed GONUTS page

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HUMAN:KCMA1

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