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Category:GO:0060072 ! large conductance calcium-activated potassium channel activity
name: large conductance calcium-activated potassium channel activity
namespace: molecular_function
alt_id: GO:0022895
def: "Enables the transmembrane transfer of potassium by a channel with a unit conductance of 100 to 220 picoSiemens that opens in response to stimulus by concerted actions of internal calcium ions and membrane potential. Large conductance calcium-activated potassium channels are less sensitive to calcium than are small or intermediate conductance calcium-activated potassium channels. Transport by a channel involves catalysis of facilitated diffusion of a solute (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel, without evidence for a carrier-mediated mechanism." [GOC:mtg_transport, ISBN:0815340729, PMID:17115074]
synonym: "BK calcium-activated potassium channel activity" EXACT []
synonym: "BK channel activity" RELATED []
synonym: "BK KCa channel activity" EXACT []
synonym: "large conductance KCa channel activity" EXACT []
is_a: GO:0015269 ! calcium-activated potassium channel activity
AmiGO
<GOterm>GO:0060072</GOterm>
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