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HUMAN:K2C1B

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Species (Taxon ID) Homo sapiens (Human). (9606)
Gene Name(s) KRT77 (synonyms: KRT1B)
Protein Name(s) Keratin, type II cytoskeletal 1b

Cytokeratin-1B CK-1B Keratin-77 K77 Type-II keratin Kb39

External Links
UniProt Q7Z794
EMBL AJ564104
AC055716
BK000975
CCDS CCDS8837.1
RefSeq NP_778253.2
UniGene Hs.334989
ProteinModelPortal Q7Z794
SMR Q7Z794
BioGrid 131903
IntAct Q7Z794
STRING 9606.ENSP00000342710
PhosphoSite Q7Z794
DMDM 308153590
MaxQB Q7Z794
PaxDb Q7Z794
PRIDE Q7Z794
Ensembl ENST00000341809
GeneID 374454
KEGG hsa:374454
UCSC uc001saw.3
CTD 374454
GeneCards GC12M053083
H-InvDB HIX0036740
HGNC HGNC:20411
HPA HPA045934
MIM 611158
neXtProt NX_Q7Z794
eggNOG NOG146126
GeneTree ENSGT00760000118796
HOGENOM HOG000230976
HOVERGEN HBG013015
InParanoid Q7Z794
KO K07605
OMA NTSHRRI
OrthoDB EOG7FV3Q8
PhylomeDB Q7Z794
TreeFam TF317854
GenomeRNAi 374454
NextBio 100191
PRO PR:Q7Z794
Proteomes UP000005640
Bgee Q7Z794
CleanEx HS_KRT77
ExpressionAtlas Q7Z794
Genevestigator Q7Z794
GO GO:0005856
GO:0070062
GO:0045095
GO:0005198
InterPro IPR001664
IPR018039
IPR003054
IPR018159
PANTHER PTHR23239
Pfam PF00038
PRINTS PR01276
SMART SM00150
PROSITE PS00226

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

part_of

GO:0070062

extracellular exosome

PMID:23533145[1]

ECO:0007005

high throughput direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005856

cytoskeleton

PMID:16117782[2]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0008150

biological_process

GO_REF:0000015

ECO:0000307

no biological data found used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0003674

molecular_function

GO_REF:0000015

ECO:0000307

no biological data found used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0005198

structural molecule activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001664

F

Seeded From UniProt

complete

part_of

GO:0005882

intermediate filament

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001664

C

Seeded From UniProt

complete

part_of

GO:0045095

keratin filament

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR003054

C

Seeded From UniProt

complete

involved_in

GO:0070268

cornification

Reactome:R-HSA-6809371

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0031424

keratinization

Reactome:R-HSA-6805567

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005829

cytosol

Reactome:R-HSA-8942224
Reactome:R-HSA-6814764
Reactome:R-HSA-6814734
Reactome:R-HSA-6814387
Reactome:R-HSA-6814298
Reactome:R-HSA-6811539
Reactome:R-HSA-6810937
Reactome:R-HSA-6810357
Reactome:R-HSA-6809663
Reactome:R-HSA-6809393
Reactome:R-HSA-6806629
Reactome:R-HSA-6806613
Reactome:R-HSA-6806610
Reactome:R-HSA-6805573
Reactome:R-HSA-6805546

ECO:0000304

author statement supported by traceable reference used in manual assertion















C

Seeded From UniProt

complete

part_of

GO:0005882

intermediate filament

GO_REF:0000037
GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0403
UniProtKB-KW:KW-0416

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Principe, S et al. (2013) In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine. Proteomics 13 1667-71 PubMed GONUTS page
  2. Langbein, L et al. (2005) Characterization of a novel human type II epithelial keratin K1b, specifically expressed in eccrine sweat glands. J. Invest. Dermatol. 125 428-44 PubMed GONUTS page