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HUMAN:ING1

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Species (Taxon ID) Homo sapiens (Human). (9606)
Gene Name(s) ING1
Protein Name(s) Inhibitor of growth protein 1
External Links
UniProt Q9UK53
EMBL AF181849
AF181850
AF001954
AF044076
AF149721
AF149722
AF149723
AF167551
AF167550
AF167551
AF167549
AB037387
AB037387
AB037387
AB037594
AB031269
AB024401
AB024402
AB024403
AB024404
AB024404
AB024405
AJ310392
AF078835
AF078837
AF078836
AK302353
AL157820
AL157820
AL157820
AL157820
CH471085
CH471085
BC093942
BC093944
CCDS CCDS9515.1
CCDS9516.1
CCDS9517.1
CCDS9518.1
RefSeq NP_001254657.1
NP_005528.4
NP_937860.1
NP_937861.1
NP_937862.1
UniGene Hs.46700
Hs.508725
PDB 2QIC
PDBsum 2QIC
ProteinModelPortal Q9UK53
SMR Q9UK53
BioGrid 109833
DIP DIP-24256N
DIP-24257N
DIP-24258N
IntAct Q9UK53
PhosphoSite Q9UK53
DMDM 212276438
MaxQB Q9UK53
PaxDb Q9UK53
PRIDE Q9UK53
Ensembl ENST00000333219
ENST00000338450
ENST00000375774
ENST00000375775
GeneID 3621
KEGG hsa:3621
UCSC uc001vrf.4
uc001vrg.3
uc001vrh.4
uc001vri.3
uc031qni.1
CTD 3621
GeneCards GC13P111365
H-InvDB HIX0056146
HGNC HGNC:6062
HPA CAB016136
CAB017773
HPA052591
MIM 275355
601566
neXtProt NX_Q9UK53
Orphanet 67037
PharmGKB PA29872
eggNOG COG5034
GeneTree ENSGT00550000074538
HOVERGEN HBG006607
InParanoid Q9UK53
OMA FETCQET
OrthoDB EOG7RBZ9T
PhylomeDB Q9UK53
TreeFam TF352014
ChiTaRS ING1
EvolutionaryTrace Q9UK53
GeneWiki ING1
GenomeRNAi 3621
NextBio 14163
PRO PR:Q9UK53
Proteomes UP000005640
Bgee Q9UK53
Genevestigator Q9UK53
GO GO:0005634
GO:0035064
GO:0008270
GO:0007049
GO:0016568
GO:0030308
GO:0008285
GO:0045893
GO:0006606
GO:0010941
Gene3D 3.30.40.10
InterPro IPR028643
IPR028651
IPR024610
IPR019786
IPR011011
IPR001965
IPR019787
IPR013083
PANTHER PTHR10333
PTHR10333:SF38
Pfam PF12998
PF00628
SMART SM00249
SUPFAM SSF57903
PROSITE PS01359
PS50016

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

enables

GO:0035064

methylated histone binding

PMID:16728974[1]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0030308

negative regulation of cell growth

PMID:8944021[2]

ECO:0000303

author statement without traceable support used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

PMID:10866301[3]

ECO:0000303

author statement without traceable support used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0045893

positive regulation of transcription, DNA-templated

PMID:21873635[4]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1349481
MGI:MGI:1916510
PANTHER:PTN002232778
UniProtKB:Q9H160

P

Seeded From UniProt

complete

enables

GO:0035064

methylated histone binding

PMID:21873635[4]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000035902
SGD:S000001132
SGD:S000005041
SGD:S000005590
TAIR:locus:2076141
UniProtKB:B3H615
UniProtKB:Q8WYH8
UniProtKB:Q9H160
UniProtKB:Q9NXR8
UniProtKB:Q9UK53
UniProtKB:Q9UNL4

F

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

PMID:21873635[4]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0038546
MGI:MGI:1349481
PANTHER:PTN002232778
UniProtKB:Q9H160

C

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR028643

C

Seeded From UniProt

complete

involved_in

GO:0008285

negative regulation of cell population proliferation

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR028643

P

Seeded From UniProt

complete

involved_in

GO:0010941

regulation of cell death

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR028643

P

Seeded From UniProt

complete

involved_in

GO:0008285

negative regulation of cell population proliferation

PMID:8944021[2]

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0539
UniProtKB-SubCell:SL-0191

C

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

involved_in

GO:0007049

cell cycle

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0131

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Shi, X et al. (2006) ING2 PHD domain links histone H3 lysine 4 methylation to active gene repression. Nature 442 96-9 PubMed GONUTS page
  2. 2.0 2.1 Garkavtsev, I et al. (1996) Suppression of the novel growth inhibitor p33ING1 promotes neoplastic transformation. Nat. Genet. 14 415-20 PubMed GONUTS page
  3. Gunduz, M et al. (2000) Genomic structure of the human ING1 gene and tumor-specific mutations detected in head and neck squamous cell carcinomas. Cancer Res. 60 3143-6 PubMed GONUTS page
  4. 4.0 4.1 4.2 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page