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HUMAN:HSP74
Contents
| Species (Taxon ID) | Homo sapiens (Human). (9606) | |
| Gene Name(s) | HSPA4 (synonyms: APG2) | |
| Protein Name(s) | Heat shock 70 kDa protein 4
HSP70RY Heat shock 70-related protein APG-2 | |
| External Links | ||
| UniProt | P34932 | |
| EMBL | AB023420 BT007375 AC113410 BC002526 BC110861 BC126122 BC126124 L12723 | |
| CCDS | CCDS4166.1 | |
| PIR | I56208 | |
| RefSeq | NP_002145.3 | |
| UniGene | Hs.90093 | |
| ProteinModelPortal | P34932 | |
| SMR | P34932 | |
| BioGrid | 109540 | |
| DIP | DIP-460N | |
| IntAct | P34932 | |
| MINT | MINT-1159519 | |
| STRING | 9606.ENSP00000302961 | |
| PhosphoSite | P34932 | |
| DMDM | 206729934 | |
| DOSAC-COBS-2DPAGE | P34932 | |
| REPRODUCTION-2DPAGE | IPI00002966 P34932 | |
| MaxQB | P34932 | |
| PaxDb | P34932 | |
| PRIDE | P34932 | |
| DNASU | 3308 | |
| Ensembl | ENST00000304858 ENST00000617819 | |
| GeneID | 3308 | |
| KEGG | hsa:3308 | |
| UCSC | uc003kyj.3 | |
| CTD | 3308 | |
| GeneCards | GC05P132415 | |
| HGNC | HGNC:5237 | |
| HPA | CAB025529 HPA010023 | |
| MIM | 601113 | |
| neXtProt | NX_P34932 | |
| PharmGKB | PA29503 | |
| eggNOG | COG0443 | |
| GeneTree | ENSGT00390000016919 | |
| HOGENOM | HOG000228138 | |
| HOVERGEN | HBG047955 | |
| InParanoid | P34932 | |
| KO | K09489 | |
| OMA | DDRNTFT | |
| OrthoDB | EOG77M8N0 | |
| PhylomeDB | P34932 | |
| TreeFam | TF105043 | |
| ChiTaRS | HSPA4 | |
| GeneWiki | HSPA4 | |
| GenomeRNAi | 3308 | |
| NextBio | 13119 | |
| PRO | PR:P34932 | |
| Proteomes | UP000005640 | |
| Bgee | P34932 | |
| CleanEx | HS_HSPA4 | |
| ExpressionAtlas | P34932 | |
| Genevestigator | P34932 | |
| GO | GO:0005829 GO:0070062 GO:0005739 GO:0005524 GO:0051131 GO:0045040 GO:0006986 | |
| Gene3D | 1.20.1270.10 2.60.34.10 | |
| InterPro | IPR018181 IPR029048 IPR029047 IPR013126 | |
| Pfam | PF00012 | |
| PRINTS | PR00301 | |
| SUPFAM | SSF100920 SSF100934 | |
| PROSITE | PS00329 PS01036 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
part_of |
GO:0070062 |
extracellular exosome |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
part_of:(CL:0000351) |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0070062 |
extracellular exosome |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0070062 |
extracellular exosome |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
C |
part_of:(CL:0000639) |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005829 |
cytosol |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0051131 |
chaperone-mediated protein complex assembly |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0045040 |
protein insertion into mitochondrial outer membrane |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006986 |
response to unfolded protein |
ECO:0000303 |
author statement without traceable support used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005524 |
ATP binding |
ECO:0000303 |
author statement without traceable support used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005829 |
cytosol |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000452854 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:105053 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0000166 |
nucleotide binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005524 |
ATP binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Atay, S et al. (2011) Morphologic and proteomic characterization of exosomes released by cultured extravillous trophoblast cells. Exp. Cell Res. 317 1192-202 PubMed GONUTS page
- ↑ 2.0 2.1 Buschow, SI et al. () MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis. Immunol. Cell Biol. 88 851-6 PubMed GONUTS page
- ↑ Hageman, J et al. (2011) The diverse members of the mammalian HSP70 machine show distinct chaperone-like activities. Biochem. J. 435 127-42 PubMed GONUTS page
- ↑ 4.0 4.1 Humphries, AD et al. (2005) Dissection of the mitochondrial import and assembly pathway for human Tom40. J. Biol. Chem. 280 11535-43 PubMed GONUTS page
- ↑ 5.0 5.1 Fathallah, DM et al. (1993) Molecular cloning of a novel human hsp70 from a B cell line and its assignment to chromosome 5. J. Immunol. 151 810-3 PubMed GONUTS page
- ↑ 6.0 6.1 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
