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HUMAN:HMGN5

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Species (Taxon ID) Homo sapiens (Human). (9606)
Gene Name(s) HMGN5 (synonyms: NSBP1)
Protein Name(s) High mobility group nucleosome-binding domain-containing protein 5

Nucleosome-binding protein 1

External Links
UniProt P82970
EMBL AF250329
AF250330
AK094058
AL391294
CH471104
BC005342
CCDS CCDS14448.1
RefSeq NP_110390.1
UniGene Hs.282204
ProteinModelPortal P82970
BioGrid 122655
IntAct P82970
STRING 9606.ENSP00000350848
PhosphoSite P82970
DMDM 23396771
MaxQB P82970
PaxDb P82970
PRIDE P82970
DNASU 79366
Ensembl ENST00000358130
GeneID 79366
KEGG hsa:79366
UCSC uc004eee.1
CTD 79366
GeneCards GC0XM080370
HGNC HGNC:8013
HPA HPA000511
MIM 300385
neXtProt NX_P82970
PharmGKB PA31789
eggNOG NOG134182
GeneTree ENSGT00730000111570
HOGENOM HOG000113856
HOVERGEN HBG094823
InParanoid P82970
KO K17045
OMA SSTHLIQ
OrthoDB EOG77T177
PhylomeDB P82970
ChiTaRS HMGN5
GenomeRNAi 79366
NextBio 68337
PRO PR:P82970
Proteomes UP000005640
Bgee P82970
CleanEx HS_NSBP1
ExpressionAtlas P82970
Genevestigator P82970
GO GO:0000785
GO:0043231
GO:0005730
GO:0005654
GO:0005634
GO:0003682
GO:0003677
GO:0044822
GO:0016568
GO:0045893
GO:0006357
GO:0006355
GO:0006351
InterPro IPR000079
Pfam PF01101
PRINTS PR00925
SMART SM00527
PROSITE PS00355

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0008284

positive regulation of cell proliferation

PMID:20531280[1]

ECO:0000315

P

Figure 2

complete
CACAO 6897

GO:0071157

negative regulation of cell cycle arrest

PMID:20531280[1]

ECO:0000315

P

Figure 3, A and B

complete
CACAO 6898

involved_in

GO:0010628

positive regulation of gene expression

PMID:20531280[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

GO:0043066

negative regulation of apoptotic process

PMID:20531280[1]

ECO:0000315

P

Figure 3, C and D

complete
CACAO 6899

involved_in

GO:0043066

negative regulation of apoptotic process

PMID:20531280[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

GO:0010628

positive regulation of gene expression

PMID:20531280[1]

ECO:0000315

P

Figure 4

complete
CACAO 6900

involved_in

GO:0071157

negative regulation of cell cycle arrest

PMID:20531280[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

GO:2001219

positive regulation of S/G2 transition of mitotic cell cycle

PMID:20531280[1]

ECO:0000315

P

Figure 3, A and B

complete
CACAO 6916

involved_in

GO:0008284

positive regulation of cell population proliferation

PMID:20531280[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0045893

positive regulation of transcription, DNA-templated

PMID:11161810[2]

ECO:0000303

author statement without traceable support used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0003723

RNA binding

PMID:22681889[3]

ECO:0007005

high throughput direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0006355

regulation of transcription, DNA-templated

PMID:11161810[2]

ECO:0000303

author statement without traceable support used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

PMID:11161810[2]

ECO:0000303

author statement without traceable support used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0003682

chromatin binding

PMID:11161810[2]

ECO:0000303

author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000052

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0000785

chromatin

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000079

C

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000079

C

Seeded From UniProt

complete

enables

GO:0031492

nucleosomal DNA binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000079

F

Seeded From UniProt

complete

involved_in

GO:0006325

chromatin organization

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0156

P

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0539
UniProtKB-SubCell:SL-0191

C

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0238

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 1.8 Jiang, N et al. (2010) Downregulation of the nucleosome-binding protein 1 (NSBP1) gene can inhibit the in vitro and in vivo proliferation of prostate cancer cells. Asian J. Androl. 12 709-17 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 King, LM & Francomano, CA (2001) Characterization of a human gene encoding nucleosomal binding protein NSBP1. Genomics 71 163-73 PubMed GONUTS page
  3. Baltz, AG et al. (2012) The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts. Mol. Cell 46 674-90 PubMed GONUTS page