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HUMAN:H32

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Species (Taxon ID) Homo sapiens (Human). (9606)
Gene Name(s) HIST2H3D (synonyms: H3F2, H3FM)
Protein Name(s) Histone H3.2

Histone H3/m Histone H3/o

External Links
UniProt Q71DI3
EMBL AF531305
AF531307
AY648851
AL591493
AL591493
AL591493
BC074969
BC130635
BC130637
CCDS CCDS30848.1
CCDS30850.1
CCDS41388.1
RefSeq NP_001005464.1
NP_001116847.1
NP_066403.2
UniGene Hs.647745
Hs.706618
Hs.712062
PDB 2IIJ
2X4W
2X4X
2X4Y
3AV1
3DB3
3MO8
3QO2
3R93
4MZF
4MZG
4MZH
4OUC
PDBsum 2IIJ
2X4W
2X4X
2X4Y
3AV1
3DB3
3MO8
3QO2
3R93
4MZF
4MZG
4MZH
4OUC
ProteinModelPortal Q71DI3
SMR Q71DI3
BioGrid 126025
130616
575920
DIP DIP-48606N
IntAct Q71DI3
MINT MINT-4828325
STRING 9606.ENSP00000333277
PhosphoSite Q71DI3
DMDM 74758899
MaxQB Q71DI3
PaxDb Q71DI3
PRIDE Q71DI3
DNASU 126961
Ensembl ENST00000331491
ENST00000369158
ENST00000403683
GeneID 126961
333932
653604
KEGG hsa:126961
hsa:333932
hsa:653604
UCSC uc001esv.3
CTD 126961
333932
653604
GeneCards GC01M149784
GC01M149812
GC01P149824
HGNC HGNC:20505
HGNC:20503
HGNC:25311
HPA HPA042570
MIM 142780
neXtProt NX_Q71DI3
PharmGKB PA145148728
eggNOG COG2036
GeneTree ENSGT00760000118967
HOGENOM HOG000155290
HOVERGEN HBG001172
InParanoid Q71DI3
KO K11253
OMA RISKMAR
OrthoDB EOG7HB5C2
PhylomeDB Q71DI3
TreeFam TF314241
Reactome REACT_169168
REACT_169436
REACT_172610
REACT_172744
REACT_200753
REACT_200808
REACT_200827
REACT_200856
REACT_2204
REACT_2232
REACT_228108
REACT_228178
REACT_228222
REACT_24970
REACT_267652
REACT_267668
REACT_27271
REACT_75925
ChiTaRS HIST2H3C
EvolutionaryTrace Q71DI3
GeneWiki HIST2H3C
NextBio 81962
Proteomes UP000005640
Bgee Q71DI3
CleanEx HS_HIST2H3A
HS_HIST2H3C
HS_HIST2H3D
ExpressionAtlas Q71DI3
Genevestigator Q71DI3
GO GO:0005576
GO:0070062
GO:0005654
GO:0000786
GO:0005634
GO:0003677
GO:0007596
Gene3D 1.10.20.10
InterPro IPR009072
IPR007125
IPR000164
PANTHER PTHR11426
Pfam PF00125
PRINTS PR00622
SMART SM00428
SUPFAM SSF47113
PROSITE PS00322
PS00959

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0006334

nucleosome assembly

PMID:25615412[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0000786

nucleosome

PMID:25615412[1]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0006334

nucleosome assembly

PMID:21636898[2]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0000786

nucleosome

PMID:21636898[2]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

PMID:21636898[2]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0070062

extracellular exosome

PMID:19199708[3]

ECO:0007005

high throughput direct assay evidence used in manual assertion

C

part_of:(UBERON:0001831)

Seeded From UniProt

complete

part_of

GO:0070062

extracellular exosome

PMID:20458337[4]

ECO:0007005

high throughput direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0070062

extracellular exosome

PMID:20458337[4]

ECO:0007005

high throughput direct assay evidence used in manual assertion

C

part_of:(CL:0000639)

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

PMID:21630459[5]

ECO:0007005

high throughput direct assay evidence used in manual assertion

C

part_of:(CL:0000019)

Seeded From UniProt

complete

enables

GO:0031492

nucleosomal DNA binding

PMID:21873635[6]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000152096
UniProtKB:Q6NXT2

F

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

PMID:21873635[6]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000152096
TAIR:locus:2035252
TAIR:locus:2035415
UniProtKB:P49450
UniProtKB:P59169
UniProtKB:P68431
UniProtKB:Q71DI3
WB:WBGene00001831
WB:WBGene00001946
WB:WBGene00010036
dictyBase:DDB_G0271092

C

Seeded From UniProt

complete

part_of

GO:0000786

nucleosome

PMID:21873635[6]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0004828
PANTHER:PTN000152096
UniProtKB:P68431
UniProtKB:P84243
UniProtKB:Q16695
UniProtKB:Q6PI20
UniProtKB:Q71DI3
WB:WBGene00001946

C

Seeded From UniProt

complete

part_of

GO:0000786

nucleosome

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000164
InterPro:IPR007125

C

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000164
InterPro:IPR007125

F

Seeded From UniProt

complete

enables

GO:0046982

protein heterodimerization activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR009072

F

Seeded From UniProt

complete

involved_in

GO:0060964

regulation of gene silencing by miRNA

Reactome:R-HSA-5578749

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0045814

negative regulation of gene expression, epigenetic

Reactome:R-HSA-212300

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0045652

regulation of megakaryocyte differentiation

Reactome:R-HSA-8936459

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0044267

cellular protein metabolic process

Reactome:R-HSA-392499

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0038111

interleukin-7-mediated signaling pathway

Reactome:R-HSA-1266695

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0007596

blood coagulation

Reactome:R-HSA-109582

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0006325

chromatin organization

Reactome:R-HSA-4839726

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005654

nucleoplasm

Reactome:R-HSA-997263
Reactome:R-HSA-994106
Reactome:R-HSA-9012000
Reactome:R-HSA-9011985
Reactome:R-HSA-9011984
Reactome:R-HSA-9011983
Reactome:R-HSA-9011981
Reactome:R-HSA-9011952
Reactome:R-HSA-9011949
Reactome:R-HSA-9009371
Reactome:R-HSA-9009065
Reactome:R-HSA-8937118
Reactome:R-HSA-8937113
Reactome:R-HSA-8937050
Reactome:R-HSA-8937037
Reactome:R-HSA-8937022
Reactome:R-HSA-8937016
Reactome:R-HSA-8936989
Reactome:R-HSA-8936979
Reactome:R-HSA-8936621
Reactome:R-HSA-8936616
Reactome:R-HSA-8936608
Reactome:R-HSA-8936599
Reactome:R-HSA-8936584
Reactome:R-HSA-8936481
Reactome:R-HSA-8935740
Reactome:R-HSA-8935730
Reactome:R-HSA-8865613
Reactome:R-HSA-5625870
Reactome:R-HSA-5625849
Reactome:R-HSA-5625848
Reactome:R-HSA-5625797
Reactome:R-HSA-5625796
Reactome:R-HSA-5625784
Reactome:R-HSA-5625774
Reactome:R-HSA-5578742
Reactome:R-HSA-5250938
Reactome:R-HSA-427528
Reactome:R-HSA-427527
Reactome:R-HSA-427514
Reactome:R-HSA-427337
Reactome:R-HSA-3788748
Reactome:R-HSA-3788745
Reactome:R-HSA-3240295
Reactome:R-HSA-3229102
Reactome:R-HSA-3229089
Reactome:R-HSA-3222593
Reactome:R-HSA-212269
Reactome:R-HSA-212263
Reactome:R-HSA-212252
Reactome:R-HSA-212222

ECO:0000304

author statement supported by traceable reference used in manual assertion



















































C

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

Reactome:R-HSA-977224

ECO:0000304

author statement supported by traceable reference used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0000183

chromatin silencing at rDNA

Reactome:R-HSA-427413
Reactome:R-HSA-427359

ECO:0000304

author statement supported by traceable reference used in manual assertion


P

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0238

F

Seeded From UniProt

complete

part_of

GO:0005694

chromosome

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0158
UniProtKB-SubCell:SL-0468

C

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0539
UniProtKB-SubCell:SL-0191

C

Seeded From UniProt

complete

part_of

GO:0000786

nucleosome

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0544

C

Seeded From UniProt

complete

edit table

Notes

References

See Help:References for how to manage references in GONUTS.

  1. ↑ 1.0 1.1 Kato, D et al. (2015) Human tNASP promotes in vitro nucleosome assembly with histone H3.3. Biochemistry 54 1171-9 PubMed GONUTS page
  2. ↑ 2.0 2.1 2.2 Tachiwana, H et al. (2011) Structures of human nucleosomes containing major histone H3 variants. Acta Crystallogr. D Biol. Crystallogr. 67 578-83 PubMed GONUTS page
  3. ↑ Gonzalez-Begne, M et al. (2009) Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT). J. Proteome Res. 8 1304-14 PubMed GONUTS page
  4. ↑ 4.0 4.1 Buschow, SI et al. () MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis. Immunol. Cell Biol. 88 851-6 PubMed GONUTS page
  5. ↑ de Mateo, S et al. (2011) Proteomic characterization of the human sperm nucleus. Proteomics 11 2714-26 PubMed GONUTS page
  6. ↑ 6.0 6.1 6.2 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
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