HUMAN:H2AX

Species (Taxon ID)	Homo sapiens (Human). (9606)
Gene Name(s)	H2AFX (synonyms: H2AX)
Protein Name(s)	Histone H2AX H2a/x Histone H2A.X
External Links
UniProt	P16104
EMBL	X14850 CR457079 DQ015918 BC004915 BC011694 BC013416
CCDS	CCDS8410.1
PIR	S07631
RefSeq	NP_002096.1
UniGene	Hs.477879
PDB	1YDP 2AZM 2D31 2DYP 3SHV 3SQD 3SZM 3U3Z
PDBsum	1YDP 2AZM 2D31 2DYP 3SHV 3SQD 3SZM 3U3Z
ProteinModelPortal	P16104
SMR	P16104
BioGrid	109268
DIP	DIP-33604N
IntAct	P16104
MINT	MINT-1338182
STRING	9606.ENSP00000364310
PhosphoSite	P16104
DMDM	121992
MaxQB	P16104
PaxDb	P16104
PRIDE	P16104
Ensembl	ENST00000375167 ENST00000530167
GeneID	3014
KEGG	hsa:3014
UCSC	uc001pvg.3
CTD	3014
GeneCards	GC11M118964
HGNC	HGNC:4739
HPA	CAB012264
MIM	601772
neXtProt	NX_P16104
PharmGKB	PA29116
eggNOG	COG5262
GeneTree	ENSGT00760000118934
HOGENOM	HOG000234652
HOVERGEN	HBG009342
InParanoid	P16104
KO	K11251
OMA	TVGPKTP
OrthoDB	EOG7M0NTR
PhylomeDB	P16104
TreeFam	TF300137
Reactome	REACT_169168 REACT_169185 REACT_169436 REACT_172744 REACT_1884 REACT_1924 REACT_200753 REACT_200808 REACT_200827 REACT_200856 REACT_2204 REACT_22186 REACT_2232 REACT_228108 REACT_267652 REACT_267668 REACT_27271 REACT_486 REACT_75792 REACT_75925 REACT_7963 REACT_97
ChiTaRS	H2AFX
EvolutionaryTrace	P16104
GeneWiki	H2AFX
GenomeRNAi	3014
NextBio	11948
PRO	PR:P16104
Proteomes	UP000005640
Bgee	P16104
CleanEx	HS_H2AFX
Genevestigator	P16104
GO	GO:0000794 GO:0070062 GO:0001673 GO:0000790 GO:0005654 GO:0000786 GO:0005634 GO:0005657 GO:0035861 GO:0001741 GO:0003684 GO:0003677 GO:0019899 GO:0042393 GO:0006974 GO:0000077 GO:0006281 GO:0006302 GO:0000724 GO:0051321 GO:0006334 GO:0045739 GO:0010212 GO:0007283
Gene3D	1.10.20.10
InterPro	IPR009072 IPR007125 IPR002119
Pfam	PF00125
PRINTS	PR00620
SMART	SM00414
SUPFAM	SSF47113
PROSITE	PS00046

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
part_of	GO:0090734	site of DNA damage	PMID:27248496^[1]	ECO:0000315	mutant phenotype evidence used in manual assertion		C	part_of:(GO:0005634)	Seeded From UniProt	complete
involved_in	GO:0006974	cellular response to DNA damage stimulus	PMID:27248496^[1]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	occurs_at:(GO:0005634)	Seeded From UniProt	complete
part_of	GO:0005813	centrosome	PMID:17498979^[2]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:19734146^[3]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:24507776^[4]	ECO:0000315	mutant phenotype evidence used in manual assertion		C	part_of:(GO:0006974)	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:16319397^[5]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0070062	extracellular exosome	PMID:23533145^[6]	ECO:0007005	high throughput direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:21630459^[7]	ECO:0007005	high throughput direct assay evidence used in manual assertion		C	part_of:(CL:0000019)	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:23235539^[8]	ECO:0000314	direct assay evidence used in manual assertion		C	exists_during:(GO:0006974)	Seeded From UniProt	complete
involved_in	GO:0006974	cellular response to DNA damage stimulus	PMID:15149599^[9]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
colocalizes_with	GO:0000781	chromosome, telomeric region	PMID:15149599^[9]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0045739	positive regulation of DNA repair	PMID:19234442^[10]	ECO:0000303	author statement without traceable support used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0042393	histone binding	PMID:19234442^[10]	ECO:0000353	physical interaction evidence used in manual assertion	UniProtKB:O00213	F		Seeded From UniProt	complete
enables	GO:0019899	enzyme binding	PMID:19234442^[10]	ECO:0000353	physical interaction evidence used in manual assertion	UniProtKB:Q99504	F		Seeded From UniProt	complete
involved_in	GO:0010212	response to ionizing radiation	PMID:19234442^[10]	ECO:0000303	author statement without traceable support used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0006334	nucleosome assembly	PMID:2587254^[11]	ECO:0000303	author statement without traceable support used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0006302	double-strand break repair	PMID:19234442^[10]	ECO:0000303	author statement without traceable support used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:17974976^[12]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
enables	GO:0003677	DNA binding	PMID:2587254^[11]	ECO:0000303	author statement without traceable support used in manual assertion		F		Seeded From UniProt	complete
involved_in	GO:0000077	DNA damage checkpoint	PMID:17974976^[12]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0006974	cellular response to DNA damage stimulus	PMID:21873635^[13]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000605098 UniProtKB:P16104	P		Seeded From UniProt	complete
involved_in	GO:0006325	chromatin organization	PMID:21873635^[13]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:2448285 PANTHER:PTN000604564 PomBase:SPBC11B10.10c	P		Seeded From UniProt	complete
enables	GO:0003677	DNA binding	PMID:21873635^[13]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	CGD:CAL0000179664 PANTHER:PTN000604564 UniProtKB:O97320 UniProtKB:Q7L7L0	F		Seeded From UniProt	complete
part_of	GO:0000790	nuclear chromatin	PMID:21873635^[13]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:102688 PANTHER:PTN000604564 SGD:S000005372 UniProtKB:O75367 UniProtKB:Q9P0M6	C		Seeded From UniProt	complete
part_of	GO:0035861	site of double-strand break	PMID:21270334^[14]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:15604234^[15]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:11331621^[16]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0016607	nuclear speck	GO_REF:0000052	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005654	nucleoplasm	GO_REF:0000052	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0090398	cellular senescence	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:D3ZXP3 ensembl:ENSRNOP00000056469	P		Seeded From UniProt	complete
involved_in	GO:0071480	cellular response to gamma radiation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:D3ZXP3 ensembl:ENSRNOP00000056469	P		Seeded From UniProt	complete
involved_in	GO:0021987	cerebral cortex development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:D3ZXP3 ensembl:ENSRNOP00000056469	P		Seeded From UniProt	complete
involved_in	GO:0007283	spermatogenesis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:D3ZXP3 ensembl:ENSRNOP00000056469	P		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:D3ZXP3 ensembl:ENSRNOP00000056469	C		Seeded From UniProt	complete
part_of	GO:0035861	site of double-strand break	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P27661 ensembl:ENSMUSP00000051432	C		Seeded From UniProt	complete
involved_in	GO:0007283	spermatogenesis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P27661 ensembl:ENSMUSP00000051432	P		Seeded From UniProt	complete
involved_in	GO:0006281	DNA repair	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P27661 ensembl:ENSMUSP00000051432	P		Seeded From UniProt	complete
part_of	GO:0005694	chromosome	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P27661 ensembl:ENSMUSP00000051432	C		Seeded From UniProt	complete
part_of	GO:0005657	replication fork	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P27661 ensembl:ENSMUSP00000051432	C		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P27661 ensembl:ENSMUSP00000051432	C		Seeded From UniProt	complete
enables	GO:0003684	damaged DNA binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P27661 ensembl:ENSMUSP00000051432	F		Seeded From UniProt	complete
part_of	GO:0001741	XY body	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P27661 ensembl:ENSMUSP00000051432	C		Seeded From UniProt	complete
part_of	GO:0001673	male germ cell nucleus	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P27661 ensembl:ENSMUSP00000051432	C		Seeded From UniProt	complete
part_of	GO:0000794	condensed nuclear chromosome	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P27661 ensembl:ENSMUSP00000051432	C		Seeded From UniProt	complete
part_of	GO:0000790	nuclear chromatin	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P27661 ensembl:ENSMUSP00000051432	C		Seeded From UniProt	complete
part_of	GO:0000785	chromatin	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P27661 ensembl:ENSMUSP00000051432	C		Seeded From UniProt	complete
involved_in	GO:0000724	double-strand break repair via homologous recombination	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P27661 ensembl:ENSMUSP00000051432	P		Seeded From UniProt	complete
part_of	GO:0000786	nucleosome	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR002119 InterPro:IPR007125	C		Seeded From UniProt	complete
enables	GO:0003677	DNA binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR002119 InterPro:IPR007125	F		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR002119	C		Seeded From UniProt	complete
enables	GO:0046982	protein heterodimerization activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR009072	F		Seeded From UniProt	complete
involved_in	GO:0006303	double-strand break repair via nonhomologous end joining	Reactome:R-HSA-5693571	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0005654	nucleoplasm	Reactome:R-HSA-69891 Reactome:R-HSA-5693602 Reactome:R-HSA-5693599 Reactome:R-HSA-5693583 Reactome:R-HSA-5693566 Reactome:R-HSA-5693551 Reactome:R-HSA-5693549 Reactome:R-HSA-5693536 Reactome:R-HSA-5686900 Reactome:R-HSA-5686704 Reactome:R-HSA-5686685 Reactome:R-HSA-5684071 Reactome:R-HSA-5684052 Reactome:R-HSA-5683986 Reactome:R-HSA-5683967 Reactome:R-HSA-5683964 Reactome:R-HSA-5683930 Reactome:R-HSA-5683801 Reactome:R-HSA-5683735 Reactome:R-HSA-5683425 Reactome:R-HSA-5683405 Reactome:R-HSA-5683385 Reactome:R-HSA-5683384 Reactome:R-HSA-5683077 Reactome:R-HSA-5682992 Reactome:R-HSA-5682983 Reactome:R-HSA-5682967 Reactome:R-HSA-5682965 Reactome:R-HSA-5682863 Reactome:R-HSA-5682858 Reactome:R-HSA-5682629 Reactome:R-HSA-5682607 Reactome:R-HSA-5682598 Reactome:R-HSA-5682588 Reactome:R-HSA-5682586	ECO:0000304	author statement supported by traceable reference used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005694	chromosome	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0158 UniProtKB-SubCell:SL-0468	C		Seeded From UniProt	complete
involved_in	GO:0051321	meiotic cell cycle	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0469	P		Seeded From UniProt	complete
involved_in	GO:0007049	cell cycle	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0131	P		Seeded From UniProt	complete
part_of	GO:0000786	nucleosome	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0544	C		Seeded From UniProt	complete
involved_in	GO:0006974	cellular response to DNA damage stimulus	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0227	P		Seeded From UniProt	complete
involved_in	GO:0006281	DNA repair	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0234	P		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0539 UniProtKB-SubCell:SL-0191	C		Seeded From UniProt	complete
involved_in	GO:0006310	DNA recombination	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0233	P		Seeded From UniProt	complete
enables	GO:0003677	DNA binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0238	F		Seeded From UniProt	complete
involved_in	GO:0016032	viral process	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0945	P		Seeded From UniProt	complete
edit table

Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 Gilmore, JM et al. (2016) WDR76 Co-Localizes with Heterochromatin Related Proteins and Rapidly Responds to DNA Damage. PLoS ONE 11 e0155492 PubMed GONUTS page
↑ Zhang, S et al. (2007) Werner syndrome helicase (WRN), nuclear DNA helicase II (NDH II) and histone gammaH2AX are localized to the centrosome. Cell Biol. Int. 31 1109-21 PubMed GONUTS page
↑ Richter, K et al. (2009) Speckled-like pattern in the germinal center (SLIP-GC), a nuclear GTPase expressed in activation-induced deaminase-expressing lymphomas and germinal center B cells. J. Biol. Chem. 284 30652-61 PubMed GONUTS page
↑ Tummala, H et al. (2014) ERCC6L2 mutations link a distinct bone-marrow-failure syndrome to DNA repair and mitochondrial function. Am. J. Hum. Genet. 94 246-56 PubMed GONUTS page
↑ Bonenfant, D et al. (2006) Characterization of histone H2A and H2B variants and their post-translational modifications by mass spectrometry. Mol. Cell Proteomics 5 541-52 PubMed GONUTS page
↑ Principe, S et al. (2013) In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine. Proteomics 13 1667-71 PubMed GONUTS page
↑ de Mateo, S et al. (2011) Proteomic characterization of the human sperm nucleus. Proteomics 11 2714-26 PubMed GONUTS page
↑ Lopez, MF et al. (2012) Depletion of nuclear histone H2A variants is associated with chronic DNA damage signaling upon drug-evoked senescence of human somatic cells. Aging (Albany NY) 4 823-42 PubMed GONUTS page
↑ ^9.0 ^9.1 Herbig, U et al. (2004) Telomere shortening triggers senescence of human cells through a pathway involving ATM, p53, and p21(CIP1), but not p16(INK4a). Mol. Cell 14 501-13 PubMed GONUTS page
↑ ^10.0 ^10.1 ^10.2 ^10.3 ^10.4 Cook, PJ et al. (2009) Tyrosine dephosphorylation of H2AX modulates apoptosis and survival decisions. Nature 458 591-6 PubMed GONUTS page
↑ ^11.0 ^11.1 Mannironi, C et al. (1989) H2A.X. a histone isoprotein with a conserved C-terminal sequence, is encoded by a novel mRNA with both DNA replication type and polyA 3' processing signals. Nucleic Acids Res. 17 9113-26 PubMed GONUTS page
↑ ^12.0 ^12.1 Medina, R et al. (2007) The HiNF-P/p220NPAT cell cycle signaling pathway controls nonhistone target genes. Cancer Res. 67 10334-42 PubMed GONUTS page
↑ ^13.0 ^13.1 ^13.2 ^13.3 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
↑ Boehler, C et al. (2011) Poly(ADP-ribose) polymerase 3 (PARP3), a newcomer in cellular response to DNA damage and mitotic progression. Proc. Natl. Acad. Sci. U.S.A. 108 2783-8 PubMed GONUTS page
↑ Polci, R et al. (2004) NIMA-related protein kinase 1 is involved early in the ionizing radiation-induced DNA damage response. Cancer Res. 64 8800-3 PubMed GONUTS page
↑ Chadwick, BP & Willard, HF (2001) Histone H2A variants and the inactive X chromosome: identification of a second macroH2A variant. Hum. Mol. Genet. 10 1101-13 PubMed GONUTS page

[PMID:27248496-1] 1.0 ^1.1 Gilmore, JM et al. (2016) WDR76 Co-Localizes with Heterochromatin Related Proteins and Rapidly Responds to DNA Damage. PLoS ONE 11 e0155492 PubMed GONUTS page

[PMID:17498979-2] Zhang, S et al. (2007) Werner syndrome helicase (WRN), nuclear DNA helicase II (NDH II) and histone gammaH2AX are localized to the centrosome. Cell Biol. Int. 31 1109-21 PubMed GONUTS page

[PMID:19734146-3] Richter, K et al. (2009) Speckled-like pattern in the germinal center (SLIP-GC), a nuclear GTPase expressed in activation-induced deaminase-expressing lymphomas and germinal center B cells. J. Biol. Chem. 284 30652-61 PubMed GONUTS page

[PMID:24507776-4] Tummala, H et al. (2014) ERCC6L2 mutations link a distinct bone-marrow-failure syndrome to DNA repair and mitochondrial function. Am. J. Hum. Genet. 94 246-56 PubMed GONUTS page

[PMID:16319397-5] Bonenfant, D et al. (2006) Characterization of histone H2A and H2B variants and their post-translational modifications by mass spectrometry. Mol. Cell Proteomics 5 541-52 PubMed GONUTS page

[PMID:23533145-6] Principe, S et al. (2013) In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine. Proteomics 13 1667-71 PubMed GONUTS page

[PMID:21630459-7] Mateo, S et al. (2011) Proteomic characterization of the human sperm nucleus. Proteomics 11 2714-26 PubMed GONUTS page

[PMID:23235539-8] Lopez, MF et al. (2012) Depletion of nuclear histone H2A variants is associated with chronic DNA damage signaling upon drug-evoked senescence of human somatic cells. Aging (Albany NY) 4 823-42 PubMed GONUTS page

[PMID:15149599-9] 9.0 ^9.1 Herbig, U et al. (2004) Telomere shortening triggers senescence of human cells through a pathway involving ATM, p53, and p21(CIP1), but not p16(INK4a). Mol. Cell 14 501-13 PubMed GONUTS page

[PMID:19234442-10] 10.0 ^10.1 ^10.2 ^10.3 ^10.4 Cook, PJ et al. (2009) Tyrosine dephosphorylation of H2AX modulates apoptosis and survival decisions. Nature 458 591-6 PubMed GONUTS page

[PMID:2587254-11] 11.0 ^11.1 Mannironi, C et al. (1989) H2A.X. a histone isoprotein with a conserved C-terminal sequence, is encoded by a novel mRNA with both DNA replication type and polyA 3' processing signals. Nucleic Acids Res. 17 9113-26 PubMed GONUTS page

[PMID:17974976-12] 12.0 ^12.1 Medina, R et al. (2007) The HiNF-P/p220NPAT cell cycle signaling pathway controls nonhistone target genes. Cancer Res. 67 10334-42 PubMed GONUTS page

[PMID:21873635-13] 13.0 ^13.1 ^13.2 ^13.3 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:21270334-14] Boehler, C et al. (2011) Poly(ADP-ribose) polymerase 3 (PARP3), a newcomer in cellular response to DNA damage and mitotic progression. Proc. Natl. Acad. Sci. U.S.A. 108 2783-8 PubMed GONUTS page

[PMID:15604234-15] Polci, R et al. (2004) NIMA-related protein kinase 1 is involved early in the ionizing radiation-induced DNA damage response. Cancer Res. 64 8800-3 PubMed GONUTS page

[PMID:11331621-16] Chadwick, BP & Willard, HF (2001) Histone H2A variants and the inactive X chromosome: identification of a second macroH2A variant. Hum. Mol. Genet. 10 1101-13 PubMed GONUTS page

[1]

[2]

[3]

[4]

[5]

[6]

[7]

[8]

[9]

[10]

[11]

[12]

[13]

[14]

[15]

[16]

HUMAN:H2AX

Contents

Annotations

Notes

References

c

d

e

h

m

n

p

r

s

v

x

Navigation menu

Personal tools

Namespaces

Variants

Views

More

Search

Navigation

Cacao

Links

Tools