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HUMAN:GTR2

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Species (Taxon ID) Homo sapiens (Human). (9606)
Gene Name(s) SLC2A2 (synonyms: GLUT2)
Protein Name(s) Solute carrier family 2, facilitated glucose transporter member 2

Glucose transporter type 2, liver GLUT-2

External Links
UniProt P11168
EMBL J03810
AK290846
AK298418
AK313622
AC061708
AC092918
CH471052
CCDS CCDS3215.1
PIR A31318
RefSeq NP_000331.1
NP_001265587.1
NP_001265588.1
UniGene Hs.167584
ProteinModelPortal P11168
SMR P11168
BioGrid 112405
STRING 9606.ENSP00000323568
BindingDB P11168
ChEMBL CHEMBL5873
DrugBank DB00428
GuidetoPHARMACOLOGY 876
TCDB 2.A.1.1.29
PhosphoSite P11168
DMDM 121756
MaxQB P11168
PaxDb P11168
PRIDE P11168
Ensembl ENST00000314251
GeneID 6514
KEGG hsa:6514
UCSC uc003fhe.1
CTD 6514
GeneCards GC03M170714
HGNC HGNC:11006
HPA CAB010444
HPA028997
MIM 138160
227810
neXtProt NX_P11168
Orphanet 2088
PharmGKB PA35876
eggNOG COG0477
GeneTree ENSGT00760000119022
HOGENOM HOG000202871
HOVERGEN HBG014816
InParanoid P11168
KO K07593
OMA HVAQQFS
OrthoDB EOG7QVM2R
PhylomeDB P11168
TreeFam TF313762
Reactome REACT_13819
REACT_18325
REACT_19343
REACT_212
REACT_9441
GenomeRNAi 6514
NextBio 25331
PRO PR:P11168
Proteomes UP000005640
Bgee P11168
CleanEx HS_SLC2A2
ExpressionAtlas P11168
Genevestigator P11168
GO GO:0005903
GO:0005737
GO:0005887
GO:0016020
GO:0005886
GO:0055056
GO:0033300
GO:0005355
GO:0015149
GO:0005975
GO:0031018
GO:0006112
GO:0015758
GO:0035428
GO:0008645
GO:0050796
GO:0044281
GO:0055085
InterPro IPR002440
IPR020846
IPR005828
IPR003663
IPR005829
Pfam PF00083
PRINTS PR01191
PR00171
SUPFAM SSF103473
TIGRFAMs TIGR00879
PROSITE PS50850
PS00216
PS00217

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:1904659

glucose transmembrane transport

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P14246
ensembl:ENSMUSP00000029240

P

Seeded From UniProt

complete

involved_in

GO:0070837

dehydroascorbic acid transport

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P14246
ensembl:ENSMUSP00000029240

P

Seeded From UniProt

complete

enables

GO:0055056

D-glucose transmembrane transporter activity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P14246
ensembl:ENSMUSP00000029240

F

Seeded From UniProt

complete

enables

GO:0033300

dehydroascorbic acid transmembrane transporter activity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P14246
ensembl:ENSMUSP00000029240

F

Seeded From UniProt

complete

part_of

GO:0016324

apical plasma membrane

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P14246
ensembl:ENSMUSP00000029240

C

Seeded From UniProt

complete

part_of

GO:0005911

cell-cell junction

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P14246
ensembl:ENSMUSP00000029240

C

Seeded From UniProt

complete

part_of

GO:0005903

brush border

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P14246
ensembl:ENSMUSP00000029240

C

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P14246
ensembl:ENSMUSP00000029240

C

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P14246
ensembl:ENSMUSP00000029240

C

Seeded From UniProt

complete

enables

GO:0005215

transporter activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR005829

F

Seeded From UniProt

complete

enables

GO:0005355

glucose transmembrane transporter activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR002440

F

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR002440
InterPro:IPR003663

C

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR005828
InterPro:IPR005829

C

Seeded From UniProt

complete

enables

GO:0022857

transmembrane transporter activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR003663
InterPro:IPR005828

F

Seeded From UniProt

complete

involved_in

GO:0055085

transmembrane transport

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR003663
InterPro:IPR005828
InterPro:IPR005829

P

Seeded From UniProt

complete

involved_in

GO:1904659

glucose transmembrane transport

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR002440

P

Seeded From UniProt

complete

part_of

GO:0016020

membrane

PMID:8027028[1]

ECO:0000304

author statement supported by traceable reference used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:1904659

glucose transmembrane transport

PMID:8027028[1]
Reactome:R-HSA-8981574

ECO:0000304

author statement supported by traceable reference used in manual assertion


P

Seeded From UniProt

complete

involved_in

GO:0005975

carbohydrate metabolic process

PMID:8027028[1]

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005887

integral component of plasma membrane

PMID:8027028[1]

ECO:0000304

author statement supported by traceable reference used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0005355

glucose transmembrane transporter activity

PMID:8027028[1]

ECO:0000304

author statement supported by traceable reference used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0106001

intestinal hexose absorption

Reactome:R-HSA-8981373

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0050796

regulation of insulin secretion

Reactome:R-HSA-422356

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0008645

hexose transmembrane transport

Reactome:R-HSA-189200

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

Reactome:R-HSA-8981574
Reactome:R-HSA-499981
Reactome:R-HSA-450095
Reactome:R-HSA-189242

ECO:0000304

author statement supported by traceable reference used in manual assertion




C

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0812

C

Seeded From UniProt

complete

involved_in

GO:0008643

carbohydrate transport

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0762

P

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472
UniProtKB-SubCell:SL-0162

C

Seeded From UniProt

complete

edit table

Notes

References

See Help:References for how to manage references in GONUTS.

  1. ↑ 1.0 1.1 1.2 1.3 1.4 Mueckler, M et al. (1994) A mutation in the Glut2 glucose transporter gene of a diabetic patient abolishes transport activity. J. Biol. Chem. 269 17765-7 PubMed GONUTS page
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