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HUMAN:GOGA4
Contents
| Species (Taxon ID) | Homo sapiens (Human). (9606) | |
| Gene Name(s) | GOLGA4 | |
| Protein Name(s) | Golgin subfamily A member 4
256 kDa golgin Golgin-245 Protein 72.1 Trans-Golgi p230 | |
| External Links | ||
| UniProt | Q13439 | |
| EMBL | U41740 X82834 AC097359 AB209693 U31906 X76942 | |
| CCDS | CCDS2666.1 CCDS54564.1 | |
| RefSeq | NP_001166184.1 NP_002069.2 | |
| UniGene | Hs.344151 | |
| PDB | 1R4A 1UPT | |
| PDBsum | 1R4A 1UPT | |
| ProteinModelPortal | Q13439 | |
| SMR | Q13439 | |
| BioGrid | 109065 | |
| IntAct | Q13439 | |
| MINT | MINT-3027757 | |
| STRING | 9606.ENSP00000354486 | |
| PhosphoSite | Q13439 | |
| DMDM | 12643718 | |
| MaxQB | Q13439 | |
| PaxDb | Q13439 | |
| PRIDE | Q13439 | |
| Ensembl | ENST00000356847 ENST00000361924 | |
| GeneID | 2803 | |
| KEGG | hsa:2803 | |
| UCSC | uc003cgv.3 uc003cgx.3 | |
| CTD | 2803 | |
| GeneCards | GC03P037284 | |
| HGNC | HGNC:4427 | |
| HPA | HPA035102 HPA040675 | |
| MIM | 602509 | |
| neXtProt | NX_Q13439 | |
| PharmGKB | PA28808 | |
| eggNOG | NOG12793 | |
| GeneTree | ENSGT00730000111139 | |
| HOGENOM | HOG000112753 | |
| HOVERGEN | HBG051754 | |
| InParanoid | Q13439 | |
| OMA | STKFSEW | |
| OrthoDB | EOG72C4ZF | |
| PhylomeDB | Q13439 | |
| TreeFam | TF325082 | |
| ChiTaRS | GOLGA4 | |
| EvolutionaryTrace | Q13439 | |
| GeneWiki | GOLGA4 | |
| GenomeRNAi | 2803 | |
| NextBio | 11049 | |
| PRO | PR:Q13439 | |
| Proteomes | UP000005640 | |
| Bgee | Q13439 | |
| CleanEx | HS_GOLGA4 | |
| ExpressionAtlas | Q13439 | |
| Genevestigator | Q13439 | |
| GO | GO:0005737 GO:0070062 GO:0005794 GO:0000139 GO:0043231 GO:0005634 GO:0005802 GO:0051020 GO:0043001 GO:0000042 GO:0016192 | |
| Gene3D | 1.10.220.60 | |
| InterPro | IPR000237 | |
| Pfam | PF01465 | |
| SMART | SM00755 | |
| SUPFAM | SSF101283 | |
| PROSITE | PS50913 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0000138 |
Golgi trans cisterna |
ECO:0000314 |
C |
Figure S2A - p230 is used to measure colocalization to trans-golgi |
complete | |||||
|
involved_in |
GO:0043001 |
Golgi to plasma membrane protein transport |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0045773 |
positive regulation of axon extension |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0070062 |
extracellular exosome |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
C |
part_of:(CL:0000047) |
Seeded From UniProt |
complete | ||
|
enables |
GO:0051020 |
GTPase binding |
ECO:0000353 |
physical interaction evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0043001 |
Golgi to plasma membrane protein transport |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005794 |
Golgi apparatus |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005794 |
Golgi apparatus |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0043231 |
intracellular membrane-bounded organelle |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005829 |
cytosol |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005794 |
Golgi apparatus |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005794 |
Golgi apparatus |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q91VW5 |
C |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0043001 |
Golgi to plasma membrane protein transport |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0016192 |
vesicle-mediated transport |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005802 |
trans-Golgi network |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005829 |
cytosol |
Reactome:R-HSA-6814682 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
|
C |
Seeded From UniProt |
complete | |
|
part_of |
GO:0005794 |
Golgi apparatus |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016020 |
membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0000139 |
Golgi membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Dippold, HC et al. (2009) GOLPH3 bridges phosphatidylinositol-4- phosphate and actomyosin to stretch and shape the Golgi to promote budding. Cell 139 337-51 PubMed GONUTS page
- ↑ 2.0 2.1 Burgo, A et al. (2012) A molecular network for the transport of the TI-VAMP/VAMP7 vesicles from cell center to periphery. Dev. Cell 23 166-80 PubMed GONUTS page
- ↑ Kang, D et al. (2008) Proteomic analysis of exosomes from human neural stem cells by flow field-flow fractionation and nanoflow liquid chromatography-tandem mass spectrometry. J. Proteome Res. 7 3475-80 PubMed GONUTS page
- ↑ Panic, B et al. (2003) Structural basis for Arl1-dependent targeting of homodimeric GRIP domains to the Golgi apparatus. Mol. Cell 12 863-74 PubMed GONUTS page
- ↑ 5.0 5.1 5.2 Kakinuma, T et al. (2004) Interaction between p230 and MACF1 is associated with transport of a glycosyl phosphatidyl inositol-anchored protein from the Golgi to the cell periphery. Exp. Cell Res. 298 388-98 PubMed GONUTS page
- ↑ Nishimoto-Morita, K et al. (2009) Differential effects of depletion of ARL1 and ARFRP1 on membrane trafficking between the trans-Golgi network and endosomes. J. Biol. Chem. 284 10583-92 PubMed GONUTS page
- ↑ Erlich, R et al. (1996) Molecular characterization of trans-Golgi p230. A human peripheral membrane protein encoded by a gene on chromosome 6p12-22 contains extensive coiled-coil alpha-helical domains and a granin motif. J. Biol. Chem. 271 8328-37 PubMed GONUTS page
- ↑ Kooy, J et al. (1992) Human autoantibodies as reagents to conserved Golgi components. Characterization of a peripheral, 230-kDa compartment-specific Golgi protein. J. Biol. Chem. 267 20255-63 PubMed GONUTS page
