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HUMAN:FTMT
Contents
Species (Taxon ID) | Homo sapiens (Human). (9606) | |
Gene Name(s) | FTMT | |
Protein Name(s) | Ferritin, mitochondrial | |
External Links | ||
UniProt | Q8N4E7 | |
EMBL | BC034419 | |
CCDS | CCDS4128.1 | |
RefSeq | NP_803431.1 | |
UniGene | Hs.105324 | |
PDB | 1R03 | |
PDBsum | 1R03 | |
ProteinModelPortal | Q8N4E7 | |
SMR | Q8N4E7 | |
STRING | 9606.ENSP00000313691 | |
DMDM | 62900307 | |
PaxDb | Q8N4E7 | |
PRIDE | Q8N4E7 | |
DNASU | 94033 | |
Ensembl | ENST00000321339 | |
GeneID | 94033 | |
KEGG | hsa:94033 | |
UCSC | uc003kss.3 | |
CTD | 94033 | |
GeneCards | GC05P121187 | |
HGNC | HGNC:17345 | |
MIM | 608847 | |
neXtProt | NX_Q8N4E7 | |
PharmGKB | PA134941146 | |
eggNOG | COG1528 | |
GeneTree | ENSGT00760000119129 | |
HOGENOM | HOG000223383 | |
HOVERGEN | HBG000410 | |
InParanoid | Q8N4E7 | |
KO | K18495 | |
OMA | FLETYYL | |
OrthoDB | EOG7DRJ49 | |
PhylomeDB | Q8N4E7 | |
TreeFam | TF313885 | |
EvolutionaryTrace | Q8N4E7 | |
GeneWiki | Mitochondrial_ferritin | |
GenomeRNAi | 94033 | |
NextBio | 78343 | |
PRO | PR:Q8N4E7 | |
Proteomes | UP000005640 | |
Bgee | Q8N4E7 | |
CleanEx | HS_FTMT | |
Genevestigator | Q8N4E7 | |
GO | GO:0005739 GO:0005634 GO:0008199 GO:0004322 GO:0006879 GO:0006826 GO:0008284 GO:0051349 GO:0051353 GO:0051347 | |
Gene3D | 1.20.1260.10 | |
InterPro | IPR001519 IPR009040 IPR009078 IPR012347 IPR014034 IPR008331 | |
PANTHER | PTHR11431 | |
Pfam | PF00210 | |
SUPFAM | SSF47240 | |
PROSITE | PS00204 PS50905 |
Annotations
Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
---|---|---|---|---|---|---|---|---|---|---|
involved_in |
GO:1904231 |
positive regulation of succinate dehydrogenase activity |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:1904234 |
positive regulation of aconitate hydratase activity |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0005634 |
nucleus |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
C |
part_of:(CL:0000019) |
Seeded From UniProt |
complete | ||
involved_in |
GO:0051349 |
positive regulation of lyase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0008284 |
positive regulation of cell population proliferation |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0006879 |
cellular iron ion homeostasis |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0042802 |
identical protein binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG10921 |
F |
Seeded From UniProt |
complete | ||
enables |
GO:0008199 |
ferric iron binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG10921 |
F |
Seeded From UniProt |
complete | ||
enables |
GO:0008198 |
ferrous iron binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000153092 |
F |
Seeded From UniProt |
complete | ||
involved_in |
GO:0006880 |
intracellular sequestering of iron ion |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG10921 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0005737 |
cytoplasm |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000153092 |
C |
Seeded From UniProt |
complete | ||
enables |
GO:0005506 |
iron ion binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:95588 |
F |
Seeded From UniProt |
complete | ||
enables |
GO:0004322 |
ferroxidase activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG10921 |
F |
Seeded From UniProt |
complete | ||
involved_in |
GO:0006826 |
iron ion transport |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0006879 |
cellular iron ion homeostasis |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0008199 |
ferric iron binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0004322 |
ferroxidase activity |
ECO:0000501 |
evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0006879 |
cellular iron ion homeostasis |
Reactome:R-HSA-917937 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0005759 |
mitochondrial matrix |
Reactome:R-HSA-5691107 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
C |
Seeded From UniProt |
complete | ||
enables |
GO:0046872 |
metal ion binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0055114 |
oxidation-reduction process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0016491 |
oxidoreductase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
part_of |
GO:0005739 |
mitochondrion |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0006879 |
cellular iron ion homeostasis |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 Zanella, I et al. (2008) The effects of frataxin silencing in HeLa cells are rescued by the expression of human mitochondrial ferritin. Biochim. Biophys. Acta 1782 90-8 PubMed GONUTS page
- ↑ de Mateo, S et al. (2011) Proteomic characterization of the human sperm nucleus. Proteomics 11 2714-26 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 3.4 3.5 3.6 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
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