HUMAN:FIBG

Species (Taxon ID)	Homo sapiens (Human). (9606)
Gene Name(s)	FGG
Protein Name(s)	Fibrinogen gamma chain
External Links
UniProt	P02679
EMBL	M10014 M10014 AF118092 AF350254 AF350254 AK289422 AK290824 BT007081 CH471056 CH471056 BC007044 BC021674 X51473 X00086 K02569 K02569
CCDS	CCDS3788.1 CCDS47153.1
PIR	A90470 A90494
RefSeq	NP_000500.2 NP_068656.2
UniGene	Hs.727584
PDB	1DUG 1FIB 1FIC 1FID 1FZA 1FZB 1FZC 1FZE 1FZF 1FZG 1LT9 1LTJ 1N86 1N8E 1RE3 1RE4 1RF0 1RF1 2A45 2FFD 2FIB 2H43 2HLO 2HOD 2HPC 2HWL 2OYH 2OYI 2Q9I 2VDO 2VDP 2VDQ 2VDR 2VR3 2XNX 2XNY 2Y7L 2Z4E 3BVH 3E1I 3FIB 3GHG 3H32 3HUS 4B60
PDBsum	1DUG 1FIB 1FIC 1FID 1FZA 1FZB 1FZC 1FZE 1FZF 1FZG 1LT9 1LTJ 1N86 1N8E 1RE3 1RE4 1RF0 1RF1 2A45 2FFD 2FIB 2H43 2HLO 2HOD 2HPC 2HWL 2OYH 2OYI 2Q9I 2VDO 2VDP 2VDQ 2VDR 2VR3 2XNX 2XNY 2Y7L 2Z4E 3BVH 3E1I 3FIB 3GHG 3H32 3HUS 4B60
ProteinModelPortal	P02679
SMR	P02679
BioGrid	108557
DIP	DIP-29644N
IntAct	P02679
MINT	MINT-5004002
ChEMBL	CHEMBL2364709
DrugBank	DB00364
PhosphoSite	P02679
DMDM	20178280
DOSAC-COBS-2DPAGE	P02679
OGP	P02679
REPRODUCTION-2DPAGE	IPI00219713 P02679
SWISS-2DPAGE	P02679
MaxQB	P02679
PaxDb	P02679
PeptideAtlas	P02679
PRIDE	P02679
DNASU	2266
Ensembl	ENST00000336098 ENST00000404648
GeneID	2266
KEGG	hsa:2266
UCSC	uc003iog.3 uc003ioj.3
CTD	2266
GeneCards	GC04M155525
HGNC	HGNC:3694
HPA	HPA027529
MIM	134850 202400
neXtProt	NX_P02679
Orphanet	98880 98881 248408 101041
PharmGKB	PA430
eggNOG	NOG269667
GeneTree	ENSGT00760000118809
HOVERGEN	HBG099783
InParanoid	P02679
KO	K03905
OrthoDB	EOG7X9G60
PhylomeDB	P02679
TreeFam	TF336658
Reactome	REACT_13552 REACT_1439 REACT_15381 REACT_15523
ChiTaRS	FGG
EvolutionaryTrace	P02679
GeneWiki	FGG
GenomeRNAi	2266
NextBio	9205
PMAP-CutDB	P02679
PRO	PR:P02679
Proteomes	UP000005640
Bgee	P02679
CleanEx	HS_FGG
ExpressionAtlas	P02679
Genevestigator	P02679
GO	GO:0072562 GO:0005938 GO:0009986 GO:0009897 GO:0005576 GO:0005615 GO:0070062 GO:0005577 GO:0005886 GO:0031091 GO:0031093 GO:0050839 GO:0046872 GO:0005102 GO:0005198 GO:0007596 GO:0007160 GO:0043623 GO:0030198 GO:2000352 GO:1902042 GO:0030168 GO:0070527 GO:0002576 GO:0070374 GO:0045921 GO:0034116 GO:0090277 GO:0050714 GO:1900026 GO:0045907 GO:0051258 GO:0051592 GO:0007165
Gene3D	3.90.215.10 4.10.530.10
InterPro	IPR014716 IPR014715 IPR002181 IPR012290 IPR020837
Pfam	PF08702 PF00147
SMART	SM00186
SUPFAM	SSF56496
PROSITE	PS00514 PS51406

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
	GO:0005577	fibrinogen complex	PMID:6451630^[1]	ECO:0000314			C		Figure 6. Shows the presence of two binding sites for the D1 peptide on the NH-2 terminal region of the fibrin monomer.	complete CACAO 3722
enables	GO:0005201	extracellular matrix structural constituent	PMID:25037231^[2]	ECO:0007666	automatically integrated combinatorial computational and experimental evidence used in manual assertion		F	occurs_in:(UBERON:0001155)	Seeded From UniProt	complete
enables	GO:0005201	extracellular matrix structural constituent	PMID:28327460^[3]	ECO:0007666	automatically integrated combinatorial computational and experimental evidence used in manual assertion		F	occurs_in:(CL:0002540)	Seeded From UniProt	complete
part_of	GO:0062023	collagen-containing extracellular matrix	PMID:28327460^[3]	ECO:0007005	high throughput direct assay evidence used in manual assertion		C	part_of:(CL:0002540)	Seeded From UniProt	complete
part_of	GO:0062023	collagen-containing extracellular matrix	PMID:28344315^[4]	ECO:0007005	high throughput direct assay evidence used in manual assertion		C	part_of:(UBERON:0002371)	Seeded From UniProt	complete
enables	GO:0005201	extracellular matrix structural constituent	PMID:28344315^[4]	ECO:0007005	high throughput direct assay evidence used in manual assertion		F	occurs_in:(UBERON:0002371)	Seeded From UniProt	complete
part_of	GO:0062023	collagen-containing extracellular matrix	PMID:28675934^[5]	ECO:0007005	high throughput direct assay evidence used in manual assertion		C	part_of:(UBERON:0003688)	Seeded From UniProt	complete
enables	GO:0005201	extracellular matrix structural constituent	PMID:28675934^[5]	ECO:0007666	automatically integrated combinatorial computational and experimental evidence used in manual assertion		F	occurs_in:(UBERON:0003688)	Seeded From UniProt	complete
part_of	GO:0062023	collagen-containing extracellular matrix	PMID:25037231^[2]	ECO:0007005	high throughput direct assay evidence used in manual assertion		C	part_of:(UBERON:0002107)	Seeded From UniProt	complete
part_of	GO:0062023	collagen-containing extracellular matrix	PMID:25037231^[2]	ECO:0007005	high throughput direct assay evidence used in manual assertion		C	part_of:(UBERON:0001155)	Seeded From UniProt	complete
enables	GO:0005201	extracellular matrix structural constituent	PMID:25037231^[2]	ECO:0007666	automatically integrated combinatorial computational and experimental evidence used in manual assertion		F	occurs_in:(UBERON:0002107)	Seeded From UniProt	complete
involved_in	GO:0072378	blood coagulation, fibrin clot formation	PMID:16846481^[6]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0042730	fibrinolysis	PMID:16846481^[6]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0031639	plasminogen activation	PMID:16846481^[6]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0005577	fibrinogen complex	PMID:16846481^[6]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0009306	protein secretion	PMID:18676163^[7]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	has_direct_input:(GO:0005577)	Seeded From UniProt	complete
involved_in	GO:0072378	blood coagulation, fibrin clot formation	PMID:11001902^[8]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0005577	fibrinogen complex	PMID:18676163^[7]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005577	fibrinogen complex	PMID:6451630^[1]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0070062	extracellular exosome	PMID:23533145^[9]	ECO:0007005	high throughput direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:2000352	negative regulation of endothelial cell apoptotic process	PMID:10903502^[10]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:1902042	negative regulation of extrinsic apoptotic signaling pathway via death domain receptors	PMID:10903502^[10]	ECO:0000314	direct assay evidence used in manual assertion		P	occurs_in:(CL:0000115)	Seeded From UniProt	complete
involved_in	GO:0090277	positive regulation of peptide hormone secretion	PMID:19193866^[11]	ECO:0000314	direct assay evidence used in manual assertion		P	has_input:(UniProtKB:P05305) occurs_in:(CL:0000115)	Seeded From UniProt	complete
involved_in	GO:0070527	platelet aggregation	PMID:6281794^[12]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0070374	positive regulation of ERK1 and ERK2 cascade	PMID:10903502^[10]	ECO:0000314	direct assay evidence used in manual assertion		P	occurs_in:(CL:0000115)	Seeded From UniProt	complete
involved_in	GO:0070374	positive regulation of ERK1 and ERK2 cascade	PMID:19193866^[11]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0051258	protein polymerization	PMID:12706644^[13]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0050714	positive regulation of protein secretion	PMID:19193866^[11]	ECO:0000314	direct assay evidence used in manual assertion		P	has_input:(UniProtKB:P04275) occurs_in:(CL:0000115)	Seeded From UniProt	complete
involved_in	GO:0045921	positive regulation of exocytosis	PMID:19193866^[11]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0045907	positive regulation of vasoconstriction	PMID:15739255^[14]	ECO:0000314	direct assay evidence used in manual assertion		P	occurs_in:(UBERON:0001980) occurs_in:(UBERON:0008488)\|occurs_in:(UBERON:0000947)\|occurs_in:(UBERON:0002060)	Seeded From UniProt	complete
involved_in	GO:0034622	cellular protein-containing complex assembly	PMID:8910396^[15]	ECO:0000314	direct assay evidence used in manual assertion		P	has_direct_input:(UniProtKB:P02671) has_direct_input:(UniProtKB:P02675) has_direct_input:(UniProtKB:P02679)	Seeded From UniProt	complete
involved_in	GO:0034116	positive regulation of heterotypic cell-cell adhesion	PMID:8100742^[16]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0007160	cell-matrix adhesion	PMID:10903502^[10]	ECO:0000314	direct assay evidence used in manual assertion		P	occurs_in:(CL:0000115)	Seeded From UniProt	complete
part_of	GO:0005577	fibrinogen complex	PMID:8910396^[15]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
enables	GO:0005198	structural molecule activity	PMID:8910396^[15]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
part_of	GO:0072562	blood microparticle	PMID:22516433^[17]	ECO:0007005	high throughput direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0070062	extracellular exosome	PMID:19056867^[18]	ECO:0007005	high throughput direct assay evidence used in manual assertion		C	part_of:(UBERON:0001088)	Seeded From UniProt	complete
part_of	GO:0005615	extracellular space	PMID:16502470^[19]	ECO:0007005	high throughput direct assay evidence used in manual assertion		C	part_of:(UBERON:0001914)	Seeded From UniProt	complete
part_of	GO:0005577	fibrinogen complex	PMID:8470043^[20]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:1900026	positive regulation of substrate adhesion-dependent cell spreading	PMID:24041635^[21]	ECO:0000303	author statement without traceable support used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0051592	response to calcium ion	PMID:6777381^[22]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0050839	cell adhesion molecule binding	PMID:7822297^[23]	ECO:0000353	physical interaction evidence used in manual assertion	UniProtKB:P05362	F		Seeded From UniProt	complete
part_of	GO:0031091	platelet alpha granule	PMID:6777381^[22]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0009986	cell surface	PMID:6777381^[22]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0009897	external side of plasma membrane	PMID:6777381^[22]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005615	extracellular space	PMID:6777381^[22]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
enables	GO:0005102	signaling receptor binding	PMID:7822297^[23]	ECO:0000353	physical interaction evidence used in manual assertion	UniProtKB:P05362	F		Seeded From UniProt	complete
involved_in	GO:0090331	negative regulation of platelet aggregation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P02680 ensembl:ENSRNOP00000032735	P		Seeded From UniProt	complete
part_of	GO:0072562	blood microparticle	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P02680 ensembl:ENSRNOP00000032735	C		Seeded From UniProt	complete
involved_in	GO:0071354	cellular response to interleukin-6	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P02680 ensembl:ENSRNOP00000032735	P		Seeded From UniProt	complete
involved_in	GO:0071347	cellular response to interleukin-1	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P02680 ensembl:ENSRNOP00000032735	P		Seeded From UniProt	complete
enables	GO:0042803	protein homodimerization activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P02680 ensembl:ENSRNOP00000032735	F		Seeded From UniProt	complete
involved_in	GO:0036345	platelet maturation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P02680 ensembl:ENSRNOP00000032735	P		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P02680 ensembl:ENSRNOP00000032735	C		Seeded From UniProt	complete
enables	GO:0005102	signaling receptor binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR012290	F		Seeded From UniProt	complete
part_of	GO:0005577	fibrinogen complex	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR012290	C		Seeded From UniProt	complete
involved_in	GO:0007596	blood coagulation	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR037581	P		Seeded From UniProt	complete
involved_in	GO:0030168	platelet activation	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR012290	P		Seeded From UniProt	complete
involved_in	GO:0051258	protein polymerization	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR012290	P		Seeded From UniProt	complete
involved_in	GO:0044267	cellular protein metabolic process	Reactome:R-HSA-392499	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0043687	post-translational protein modification	Reactome:R-HSA-597592	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0031093	platelet alpha granule lumen	Reactome:R-HSA-481007	ECO:0000304	author statement supported by traceable reference used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0030198	extracellular matrix organization	Reactome:R-HSA-1474244	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0007596	blood coagulation	Reactome:R-HSA-140875	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	Reactome:R-HSA-114560	ECO:0000304	author statement supported by traceable reference used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005788	endoplasmic reticulum lumen	Reactome:R-HSA-8952289	ECO:0000304	author statement supported by traceable reference used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005576	extracellular region	Reactome:R-HSA-8870678 Reactome:R-HSA-481007 Reactome:R-HSA-429441 Reactome:R-HSA-429415 Reactome:R-HSA-377644 Reactome:R-HSA-377643 Reactome:R-HSA-377641 Reactome:R-HSA-377640 Reactome:R-HSA-372705 Reactome:R-HSA-372697 Reactome:R-HSA-372693 Reactome:R-HSA-354165 Reactome:R-HSA-354149 Reactome:R-HSA-354124 Reactome:R-HSA-354087 Reactome:R-HSA-354073 Reactome:R-HSA-354066 Reactome:R-HSA-216082 Reactome:R-HSA-216069 Reactome:R-HSA-140851 Reactome:R-HSA-140842 Reactome:R-HSA-140840 Reactome:R-HSA-114560	ECO:0000304	author statement supported by traceable reference used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0002576	platelet degranulation	Reactome:R-HSA-114608	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0002224	toll-like receptor signaling pathway	Reactome:R-HSA-168898	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0046872	metal ion binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0479	F		Seeded From UniProt	complete
part_of	GO:0005576	extracellular region	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0964 UniProtKB-SubCell:SL-0243	C		Seeded From UniProt	complete
involved_in	GO:0007599	hemostasis	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0356	P		Seeded From UniProt	complete
involved_in	GO:0007596	blood coagulation	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0094	P		Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 Olexa, SA & Budzynski, AZ (1981) Localization of a fibrin polymerization site. J. Biol. Chem. 256 3544-9 PubMed GONUTS page
↑ ^2.0 ^2.1 ^2.2 ^2.3 Naba, A et al. (2014) Extracellular matrix signatures of human primary metastatic colon cancers and their metastases to liver. BMC Cancer 14 518 PubMed GONUTS page
↑ ^3.0 ^3.1 Ragelle, H et al. (2017) Comprehensive proteomic characterization of stem cell-derived extracellular matrices. Biomaterials 128 147-159 PubMed GONUTS page
↑ ^4.0 ^4.1 Glavey, SV et al. (2017) Proteomic characterization of human multiple myeloma bone marrow extracellular matrix. Leukemia 31 2426-2434 PubMed GONUTS page
↑ ^5.0 ^5.1 Naba, A et al. (2017) Characterization of the Extracellular Matrix of Normal and Diseased Tissues Using Proteomics. J. Proteome Res. 16 3083-3091 PubMed GONUTS page
↑ ^6.0 ^6.1 ^6.2 ^6.3 Flood, VH et al. (2006) The fibrinogen Aalpha R16C mutation results in fibrinolytic resistance. Br. J. Haematol. 134 220-6 PubMed GONUTS page
↑ ^7.0 ^7.1 Platè, M et al. () Congenital hypofibrinogenemia: characterization of two missense mutations affecting fibrinogen assembly and secretion. Blood Cells Mol. Dis. 41 292-7 PubMed GONUTS page
↑ Asselta, R et al. (2000) Afibrinogenemia: first identification of a splicing mutation in the fibrinogen gamma chain gene leading to a major gamma chain truncation. Blood 96 2496-500 PubMed GONUTS page
↑ Principe, S et al. (2013) In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine. Proteomics 13 1667-71 PubMed GONUTS page
↑ ^10.0 ^10.1 ^10.2 ^10.3 Pluskota, E & D'Souza, SE (2000) Fibrinogen interactions with ICAM-1 (CD54) regulate endothelial cell survival. Eur. J. Biochem. 267 4693-704 PubMed GONUTS page
↑ ^11.0 ^11.1 ^11.2 ^11.3 Sen, U et al. (2009) Fibrinogen-induced endothelin-1 production from endothelial cells. Am. J. Physiol., Cell Physiol. 296 C840-7 PubMed GONUTS page
↑ Hawiger, J et al. (1982) gamma and alpha chains of human fibrinogen possess sites reactive with human platelet receptors. Proc. Natl. Acad. Sci. U.S.A. 79 2068-71 PubMed GONUTS page
↑ Meyer, M et al. (2003) Fibrinogen Magdeburg I: a novel variant of human fibrinogen with an amino acid exchange in the fibrinopeptide A (Aalpha 9, Leu-->Pro). Thromb. Res. 109 145-51 PubMed GONUTS page
↑ Lominadze, D et al. (2005) Fibrinogen and fragment D-induced vascular constriction. Am. J. Physiol. Heart Circ. Physiol. 288 H1257-64 PubMed GONUTS page
↑ ^15.0 ^15.1 ^15.2 Huang, S et al. (1996) The role of betagamma and alphagamma complexes in the assembly of human fibrinogen. J. Biol. Chem. 271 27942-7 PubMed GONUTS page
↑ Languino, LR et al. (1993) Fibrinogen mediates leukocyte adhesion to vascular endothelium through an ICAM-1-dependent pathway. Cell 73 1423-34 PubMed GONUTS page
↑ Bastos-Amador, P et al. (2012) Proteomic analysis of microvesicles from plasma of healthy donors reveals high individual variability. J Proteomics 75 3574-84 PubMed GONUTS page
↑ Gonzales, PA et al. (2009) Large-scale proteomics and phosphoproteomics of urinary exosomes. J. Am. Soc. Nephrol. 20 363-79 PubMed GONUTS page
↑ Palmer, DJ et al. (2006) Human colostrum: identification of minor proteins in the aqueous phase by proteomics. Proteomics 6 2208-16 PubMed GONUTS page
↑ Rosenberg, JB et al. (1993) Paris I dysfibrinogenemia: a point mutation in intron 8 results in insertion of a 15 amino acid sequence in the fibrinogen gamma-chain. Thromb. Haemost. 69 217-20 PubMed GONUTS page
↑ Snir, A et al. (2013) The role of fibrin matrices and tissue factor in early-term trophoblast proliferation and spreading. Thromb. Res. 132 477-83 PubMed GONUTS page
↑ ^22.0 ^22.1 ^22.2 ^22.3 ^22.4 Phillips, DR et al. (1980) Ca2+-mediated association of glycoprotein G (thrombinsensitive protein, thrombospondin) with human platelets. J. Biol. Chem. 255 11629-32 PubMed GONUTS page
↑ ^23.0 ^23.1 Altieri, DC et al. (1995) Structural recognition of a novel fibrinogen gamma chain sequence (117-133) by intercellular adhesion molecule-1 mediates leukocyte-endothelium interaction. J. Biol. Chem. 270 696-9 PubMed GONUTS page

[PMID:6451630-1] 1.0 ^1.1 Olexa, SA & Budzynski, AZ (1981) Localization of a fibrin polymerization site. J. Biol. Chem. 256 3544-9 PubMed GONUTS page

[PMID:25037231-2] 2.0 ^2.1 ^2.2 ^2.3 Naba, A et al. (2014) Extracellular matrix signatures of human primary metastatic colon cancers and their metastases to liver. BMC Cancer 14 518 PubMed GONUTS page

[PMID:28327460-3] 3.0 ^3.1 Ragelle, H et al. (2017) Comprehensive proteomic characterization of stem cell-derived extracellular matrices. Biomaterials 128 147-159 PubMed GONUTS page

[PMID:28344315-4] 4.0 ^4.1 Glavey, SV et al. (2017) Proteomic characterization of human multiple myeloma bone marrow extracellular matrix. Leukemia 31 2426-2434 PubMed GONUTS page

[PMID:28675934-5] 5.0 ^5.1 Naba, A et al. (2017) Characterization of the Extracellular Matrix of Normal and Diseased Tissues Using Proteomics. J. Proteome Res. 16 3083-3091 PubMed GONUTS page

[PMID:16846481-6] 6.0 ^6.1 ^6.2 ^6.3 Flood, VH et al. (2006) The fibrinogen Aalpha R16C mutation results in fibrinolytic resistance. Br. J. Haematol. 134 220-6 PubMed GONUTS page

[PMID:18676163-7] 7.0 ^7.1 Platè, M et al. () Congenital hypofibrinogenemia: characterization of two missense mutations affecting fibrinogen assembly and secretion. Blood Cells Mol. Dis. 41 292-7 PubMed GONUTS page

[PMID:11001902-8] Asselta, R et al. (2000) Afibrinogenemia: first identification of a splicing mutation in the fibrinogen gamma chain gene leading to a major gamma chain truncation. Blood 96 2496-500 PubMed GONUTS page

[PMID:23533145-9] Principe, S et al. (2013) In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine. Proteomics 13 1667-71 PubMed GONUTS page

[PMID:10903502-10] 10.0 ^10.1 ^10.2 ^10.3 Pluskota, E & D'Souza, SE (2000) Fibrinogen interactions with ICAM-1 (CD54) regulate endothelial cell survival. Eur. J. Biochem. 267 4693-704 PubMed GONUTS page

[PMID:19193866-11] 11.0 ^11.1 ^11.2 ^11.3 Sen, U et al. (2009) Fibrinogen-induced endothelin-1 production from endothelial cells. Am. J. Physiol., Cell Physiol. 296 C840-7 PubMed GONUTS page

[PMID:6281794-12] Hawiger, J et al. (1982) gamma and alpha chains of human fibrinogen possess sites reactive with human platelet receptors. Proc. Natl. Acad. Sci. U.S.A. 79 2068-71 PubMed GONUTS page

[PMID:12706644-13] Meyer, M et al. (2003) Fibrinogen Magdeburg I: a novel variant of human fibrinogen with an amino acid exchange in the fibrinopeptide A (Aalpha 9, Leu-->Pro). Thromb. Res. 109 145-51 PubMed GONUTS page

[PMID:15739255-14] Lominadze, D et al. (2005) Fibrinogen and fragment D-induced vascular constriction. Am. J. Physiol. Heart Circ. Physiol. 288 H1257-64 PubMed GONUTS page

[PMID:8910396-15] 15.0 ^15.1 ^15.2 Huang, S et al. (1996) The role of betagamma and alphagamma complexes in the assembly of human fibrinogen. J. Biol. Chem. 271 27942-7 PubMed GONUTS page

[PMID:8100742-16] Languino, LR et al. (1993) Fibrinogen mediates leukocyte adhesion to vascular endothelium through an ICAM-1-dependent pathway. Cell 73 1423-34 PubMed GONUTS page

[PMID:22516433-17] Bastos-Amador, P et al. (2012) Proteomic analysis of microvesicles from plasma of healthy donors reveals high individual variability. J Proteomics 75 3574-84 PubMed GONUTS page

[PMID:19056867-18] Gonzales, PA et al. (2009) Large-scale proteomics and phosphoproteomics of urinary exosomes. J. Am. Soc. Nephrol. 20 363-79 PubMed GONUTS page

[PMID:16502470-19] Palmer, DJ et al. (2006) Human colostrum: identification of minor proteins in the aqueous phase by proteomics. Proteomics 6 2208-16 PubMed GONUTS page

[PMID:8470043-20] Rosenberg, JB et al. (1993) Paris I dysfibrinogenemia: a point mutation in intron 8 results in insertion of a 15 amino acid sequence in the fibrinogen gamma-chain. Thromb. Haemost. 69 217-20 PubMed GONUTS page

[PMID:24041635-21] Snir, A et al. (2013) The role of fibrin matrices and tissue factor in early-term trophoblast proliferation and spreading. Thromb. Res. 132 477-83 PubMed GONUTS page

[PMID:6777381-22] 22.0 ^22.1 ^22.2 ^22.3 ^22.4 Phillips, DR et al. (1980) Ca2+-mediated association of glycoprotein G (thrombinsensitive protein, thrombospondin) with human platelets. J. Biol. Chem. 255 11629-32 PubMed GONUTS page

[PMID:7822297-23] 23.0 ^23.1 Altieri, DC et al. (1995) Structural recognition of a novel fibrinogen gamma chain sequence (117-133) by intercellular adhesion molecule-1 mediates leukocyte-endothelium interaction. J. Biol. Chem. 270 696-9 PubMed GONUTS page

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