HUMAN:EPPI

Species (Taxon ID)	Homo sapiens (Human). (9606)
Gene Name(s)	EPPIN (synonyms: SPINLW1, WAP7, WFDC7)
Protein Name(s)	Eppin Cancer/testis antigen 71 CT71 Epididymal protease inhibitor Protease inhibitor WAP7 Serine protease inhibitor-like with Kunitz and WAP domains 1 WAP four-disulfide core domain protein 7
External Links
UniProt	O95925
EMBL	AF286368 AF286369 AF286370 AL118493 AK301937 AL031663 AL031663 AL031663 BC044829 BC053369
CCDS	CCDS13359.1
RefSeq	NP_001185915.1 NP_065131.1
UniGene	Hs.121084 Hs.274876
ProteinModelPortal	O95925
SMR	O95925
IntAct	O95925
STRING	9606.ENSP00000361746
MEROPS	I02.058
PaxDb	O95925
PRIDE	O95925
DNASU	57119
Ensembl	ENST00000336443 ENST00000354280 ENST00000504988
GeneID	100526773 57119
KEGG	hsa:100526773 hsa:57119
UCSC	uc002xou.3 uc010zxc.2
CTD	100526773 57119
GeneCards	GC20M044164 GC20M044186
HGNC	HGNC:15932 HGNC:38825
MIM	609031
neXtProt	NX_O95925
PharmGKB	PA38054
eggNOG	NOG314382
GeneTree	ENSGT00730000110932
HOGENOM	HOG000115819
HOVERGEN	HBG004024
InParanoid	O95925
OMA	LAYFLRW
OrthoDB	EOG754HSR
PhylomeDB	O95925
TreeFam	TF342459
GeneWiki	SPINLW1
NextBio	62993
PRO	PR:O95925
Proteomes	UP000005640
Bgee	O95925
CleanEx	HS_SPINLW1
ExpressionAtlas	O95925
Genevestigator	O95925
GO	GO:0009986 GO:0005576 GO:0004867 GO:0042742 GO:0010466
Gene3D	4.10.410.10 4.10.75.10
InterPro	IPR002223 IPR020901 IPR008197
Pfam	PF00014 PF00095
PRINTS	PR00759
SMART	SM00131 SM00217
SUPFAM	SSF57256 SSF57362
PROSITE	PS00280 PS50279 PS51390

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
involved_in	GO:1901318	negative regulation of flagellated sperm motility	PMID:22075473	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0090281	negative regulation of calcium ion import	PMID:22075473	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0051259	protein complex oligomerization	PMID:17567961	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0005615	extracellular space	PMID:17567961	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(UBERON:0006530)	Seeded From UniProt	complete
part_of	GO:0032991	protein-containing complex	PMID:17567961	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(UBERON:0006530)|part_of:(GO:0009986) part_of:(CL:0000019)	Seeded From UniProt	complete
part_of	GO:0009986	cell surface	PMID:17567961	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(CL:0000019)	Seeded From UniProt	complete
involved_in	GO:0042742	defense response to bacterium	PMID:18331357	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0010466	negative regulation of peptidase activity	PMID:18331357	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0010466	negative regulation of peptidase activity		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN002928860 UniProtKB:O95925	P		Seeded From UniProt	complete
part_of	GO:0005615	extracellular space		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN002928860 UniProtKB:O95925	C		Seeded From UniProt	complete
involved_in	GO:0010951	negative regulation of endopeptidase activity	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0004867	P		Seeded From UniProt	complete
involved_in	GO:0010951	negative regulation of endopeptidase activity	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0004867	P		Seeded From UniProt	complete
enables	GO:0004867	serine-type endopeptidase inhibitor activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR002223 InterPro:IPR036880	F		Seeded From UniProt	complete
part_of	GO:0005576	extracellular region	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR008197	C		Seeded From UniProt	complete
enables	GO:0030414	peptidase inhibitor activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR008197	F		Seeded From UniProt	complete
part_of	GO:0097524	sperm plasma membrane	Reactome:R-HSA-6810643	ECO:0000304	author statement supported by traceable reference used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0019730	antimicrobial humoral response	Reactome:R-HSA-6803157	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0005576	extracellular region	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0964 UniProtKB-SubCell:SL-0243	C		Seeded From UniProt	complete
enables	GO:0030414	peptidase inhibitor activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0646	F		Seeded From UniProt	complete
enables	GO:0004867	serine-type endopeptidase inhibitor activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0722	F		Seeded From UniProt	complete
involved_in	GO:0010466	negative regulation of peptidase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0646	P		Seeded From UniProt	complete
part_of	GO:0009986	cell surface	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0310	C		Seeded From UniProt	complete
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