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HUMAN:ENAH

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Species (Taxon ID) Homo sapiens (Human). (9606)
Gene Name(s) ENAH (synonyms: MENA)
Protein Name(s) Protein enabled homolog
External Links
UniProt Q8N8S7
EMBL AY345143
AF519769
EU255274
AL591380
AC092811
AL356216
AL591380
AC092811
AL356216
AL356216
AC092811
AL356216
AL591380
AC092811
AL356216
AL591380
AC092811
BC065238
BC095481
AK001635
AK096246
AL133059
CCDS CCDS31040.1
CCDS31041.1
PIR T42661
RefSeq NP_001008493.1
NP_060682.2
UniGene Hs.497893
PDB 2HO2
2IYB
2XQN
4MY6
PDBsum 2HO2
2IYB
2XQN
4MY6
ProteinModelPortal Q8N8S7
SMR Q8N8S7
BioGrid 120858
IntAct Q8N8S7
MINT MINT-3041121
STRING 9606.ENSP00000355809
PhosphoSite Q8N8S7
DMDM 48428086
MaxQB Q8N8S7
PaxDb Q8N8S7
PRIDE Q8N8S7
Ensembl ENST00000366843
ENST00000366844
GeneID 55740
KEGG hsa:55740
UCSC uc001hpc.1
uc001hpd.1
CTD 55740
GeneCards GC01M225674
HGNC HGNC:18271
HPA HPA028448
HPA028696
MIM 609061
neXtProt NX_Q8N8S7
PharmGKB PA38517
eggNOG NOG289321
GeneTree ENSGT00730000110272
HOVERGEN HBG006655
InParanoid Q8N8S7
KO K05746
OrthoDB EOG72JWGQ
PhylomeDB Q8N8S7
TreeFam TF321411
Reactome REACT_12623
REACT_19351
ChiTaRS ENAH
EvolutionaryTrace Q8N8S7
GeneWiki ENAH_(gene)
GenomeRNAi 55740
NextBio 35488942
PRO PR:Q8N8S7
Proteomes UP000005640
Bgee Q8N8S7
CleanEx HS_ENAH
Genevestigator Q8N8S7
GO GO:0030054
GO:0005737
GO:0005829
GO:0030175
GO:0005925
GO:0030027
GO:0005886
GO:0001725
GO:0045202
GO:0050699
GO:0008154
GO:0007411
GO:0046907
GO:0001843
GO:0050852
Gene3D 2.30.29.30
InterPro IPR011993
IPR000156
IPR014885
IPR000697
Pfam PF08776
PF00568
SMART SM00160
SM00461
PROSITE PS50229

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

part_of

GO:0005925

focal adhesion

PMID:21423176[1]

ECO:0007005

high throughput direct assay evidence used in manual assertion

C

part_of:(CL:0000057)

Seeded From UniProt

complete

enables

GO:0050699

WW domain binding

PMID:17686488[2]

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:O00213

F

Seeded From UniProt

complete

part_of

GO:0030054

cell junction

GO_REF:0000052

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005925

focal adhesion

GO_REF:0000052

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

GO_REF:0000052

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005829

cytosol

GO_REF:0000052

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0007411

axon guidance

Reactome:R-HSA-422475

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005829

cytosol

Reactome:R-HSA-428534

ECO:0000304

author statement supported by traceable reference used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0042995

cell projection

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0966

C

Seeded From UniProt

complete

part_of

GO:0045202

synapse

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0770
UniProtKB-SubCell:SL-0258

C

Seeded From UniProt

complete

part_of

GO:0005856

cytoskeleton

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0206
UniProtKB-SubCell:SL-0090

C

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

enables

GO:0003779

actin binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0009

F

Seeded From UniProt

complete

part_of

GO:0030054

cell junction

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0965

C

Seeded From UniProt

complete

enables

GO:0017124

SH3 domain binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0729

F

Seeded From UniProt

complete

part_of

GO:0030175

filopodium

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0286

C

Seeded From UniProt

complete

part_of

GO:0030027

lamellipodium

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0291

C

Seeded From UniProt

complete

part_of

GO:0005925

focal adhesion

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0118

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Kuo, JC et al. (2011) Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation. Nat. Cell Biol. 13 383-93 PubMed GONUTS page
  2. Meiyappan, M et al. (2007) Structural basis for polyproline recognition by the FE65 WW domain. J. Mol. Biol. 372 970-80 PubMed GONUTS page