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HUMAN:EFGM
Contents
| Species (Taxon ID) | Homo sapiens (Human). (9606) | |
| Gene Name(s) | GFM1 (ECO:0000255 with HAMAP-Rule:MF_03061) (synonyms: EFG, EFG1 (ECO:0000255 with HAMAP-Rule:MF_03061), GFM) | |
| Protein Name(s) | Elongation factor G, mitochondrial (ECO:0000255 with HAMAP-Rule:MF_03061)
EF-Gmt (ECO:0000255 with HAMAP-Rule:MF_03061) Elongation factor G 1, mitochondrial (ECO:0000255 with HAMAP-Rule:MF_03061) mEF-G 1 (ECO:0000255 with HAMAP-Rule:MF_03061) Elongation factor G1 (ECO:0000255 with HAMAP-Rule:MF_03061) hEFG1 | |
| External Links | ||
| UniProt | Q96RP9 | |
| EMBL | AF309777 AF367998 AK092293 AK315031 AC080013 CH471052 CH471052 BC049210 | |
| CCDS | CCDS33885.1 | |
| RefSeq | NP_079272.4 | |
| UniGene | Hs.518355 | |
| ProteinModelPortal | Q96RP9 | |
| SMR | Q96RP9 | |
| BioGrid | 124551 | |
| IntAct | Q96RP9 | |
| STRING | 9606.ENSP00000419038 | |
| PhosphoSite | Q96RP9 | |
| DMDM | 116241346 | |
| MaxQB | Q96RP9 | |
| PaxDb | Q96RP9 | |
| PRIDE | Q96RP9 | |
| Ensembl | ENST00000264263 ENST00000486715 | |
| GeneID | 85476 | |
| KEGG | hsa:85476 | |
| UCSC | uc003fce.3 uc003fcg.3 | |
| CTD | 85476 | |
| GeneCards | GC03P158362 | |
| HGNC | HGNC:13780 | |
| HPA | HPA034765 | |
| MIM | 606639 609060 | |
| neXtProt | NX_Q96RP9 | |
| Orphanet | 137681 | |
| PharmGKB | PA134971637 | |
| eggNOG | COG0480 | |
| GeneTree | ENSGT00550000074911 | |
| HOGENOM | HOG000231585 | |
| InParanoid | Q96RP9 | |
| KO | K02355 | |
| OMA | AFQLAAI | |
| OrthoDB | EOG7VDXNM | |
| PhylomeDB | Q96RP9 | |
| TreeFam | TF105631 | |
| Reactome | REACT_267677 | |
| UniPathway | UPA00345 | |
| ChiTaRS | GFM1 | |
| GeneWiki | GFM1 | |
| GenomeRNAi | 85476 | |
| NextBio | 76132 | |
| PRO | PR:Q96RP9 | |
| Proteomes | UP000005640 | |
| Bgee | Q96RP9 | |
| CleanEx | HS_GFM1 | |
| ExpressionAtlas | Q96RP9 | |
| Genevestigator | Q96RP9 | |
| GO | GO:0005739 GO:0005525 GO:0003924 GO:0044822 GO:0003746 GO:0006184 GO:0070125 | |
| Gene3D | 3.30.230.10 3.30.70.240 3.40.50.300 | |
| HAMAP | MF_00054_B | |
| InterPro | IPR000795 IPR009022 IPR000640 IPR027417 IPR020568 IPR014721 IPR005225 IPR009000 IPR004540 IPR005517 IPR004161 | |
| Pfam | PF00679 PF14492 PF03764 PF00009 PF03144 | |
| PRINTS | PR00315 | |
| SMART | SM00838 SM00889 | |
| SUPFAM | SSF50447 SSF52540 SSF54211 SSF54980 | |
| TIGRFAMs | TIGR00484 TIGR00231 | |
| PROSITE | PS00301 PS51722 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0003746 |
translation elongation factor activity |
ECO:0000247 |
UniProtKB:Q8K0D5 UniProtKB:Q07803
|
F |
Fig. 1 and the Paragraphs below it. |
complete | ||||
|
involved_in |
GO:0070125 |
mitochondrial translational elongation |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003723 |
RNA binding |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003924 |
GTPase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003746 |
translation elongation factor activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0070125 |
mitochondrial translational elongation |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000563009 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005739 |
mitochondrion |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0263133 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0003924 |
GTPase activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN002462392 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0003746 |
translation elongation factor activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN002462392 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0003746 |
translation elongation factor activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003924 |
GTPase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005525 |
GTP binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR000795 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006414 |
translational elongation |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003746 |
translation elongation factor activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000369139 |
F |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005739 |
mitochondrion |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000369139 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0003924 |
GTPase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000369139 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0005525 |
GTP binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000369139 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0070125 |
mitochondrial translational elongation |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000369139 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0070125 |
mitochondrial translational elongation |
Reactome:R-HSA-5389840 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005759 |
mitochondrial matrix |
Reactome:R-HSA-5419261 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0005525 |
GTP binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006414 |
translational elongation |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniProtKB-KW:KW-0251 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0003746 |
translation elongation factor activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005739 |
mitochondrion |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006412 |
translation |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0000166 |
nucleotide binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Gao, J et al. (2001) Cloning and characterization of human and mouse mitochondrial elongation factor G, GFM and Gfm, and mapping of GFM to human chromosome 3q25.1-q26.2. Genomics 74 109-14 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 Tsuboi, M et al. (2009) EF-G2mt is an exclusive recycling factor in mammalian mitochondrial protein synthesis. Mol. Cell 35 502-10 PubMed GONUTS page
- ↑ Castello, A et al. (2012) Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. Cell 149 1393-406 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 4.3 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
