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HUMAN:DPP9
Contents
| Species (Taxon ID) | Homo sapiens (Human). (9606) | |
| Gene Name(s) | DPP9 (synonyms: DPRP2) | |
| Protein Name(s) | Dipeptidyl peptidase 9
DP9 Dipeptidyl peptidase IV-related protein 2 DPRP-2 Dipeptidyl peptidase IX DPP IX Dipeptidyl peptidase-like protein 9 DPLP9 | |
| External Links | ||
| UniProt | Q86TI2 | |
| EMBL | AF452102 AY172660 AF542510 AY374518 DQ417928 AK054656 AK075030 AK122654 AK131100 AK131499 AC005594 AC005783 CH471139 CH471139 BC000970 BC037948 AL834376 CR627380 | |
| CCDS | CCDS45928.1 | |
| RefSeq | NP_631898.3 XP_005259730.1 XP_011526710.1 XP_011526712.1 XP_011526713.1 | |
| UniGene | Hs.515081 | |
| ProteinModelPortal | Q86TI2 | |
| SMR | Q86TI2 | |
| BioGrid | 124789 | |
| MINT | MINT-4535936 | |
| STRING | 9606.ENSP00000262960 | |
| BindingDB | Q86TI2 | |
| ChEMBL | CHEMBL4793 | |
| ESTHER | human-DPP9 | |
| MEROPS | S09.019 | |
| PhosphoSite | Q86TI2 | |
| DMDM | 67460390 | |
| MaxQB | Q86TI2 | |
| PaxDb | Q86TI2 | |
| PRIDE | Q86TI2 | |
| DNASU | 91039 | |
| Ensembl | ENST00000262960 ENST00000594671 ENST00000598800 | |
| GeneID | 91039 | |
| KEGG | hsa:91039 | |
| UCSC | uc002mba.3 | |
| CTD | 91039 | |
| GeneCards | DPP9 | |
| H-InvDB | HIX0027578 | |
| HGNC | HGNC:18648 | |
| HPA | HPA036059 | |
| MIM | 608258 | |
| neXtProt | NX_Q86TI2 | |
| Orphanet | 2032 | |
| PharmGKB | PA38620 | |
| eggNOG | COG1506 | |
| GeneTree | ENSGT00760000119233 | |
| HOGENOM | HOG000006870 | |
| HOVERGEN | HBG061620 | |
| InParanoid | Q86TI2 | |
| KO | K08656 | |
| OMA | DGRARCY | |
| OrthoDB | EOG7XWPN8 | |
| PhylomeDB | Q86TI2 | |
| TreeFam | TF313309 | |
| SABIO-RK | Q86TI2 | |
| ChiTaRS | DPP9 | |
| GeneWiki | DPP9 | |
| GenomeRNAi | 91039 | |
| NextBio | 77078 | |
| PRO | PR:Q86TI2 | |
| Proteomes | UP000005640 | |
| Bgee | Q86TI2 | |
| ExpressionAtlas | Q86TI2 | |
| Genevisible | Q86TI2 | |
| GO | GO:0005737 GO:0005829 GO:0016020 GO:0005634 GO:0004177 GO:0042802 GO:0008236 | |
| Gene3D | 2.140.10.30 3.40.50.1820 | |
| InterPro | IPR029058 IPR001375 IPR002469 | |
| Pfam | PF00930 PF00326 | |
| SUPFAM | SSF53474 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0005874 |
microtubule |
ECO:0000314 |
C |
Figure 1 D shows microtubule florescence (red), GFP florescence of DPP9 (green), and an overlay of these images in which yellow florescence shows overlapping. This yellow florescence shows that DPP9 is present in the microtubules. |
complete | |||||
|
enables |
GO:0042802 |
identical protein binding |
ECO:0000353 |
physical interaction evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
| GO:0031252 |
cell leading edge |
ECO:0000314 |
C |
Figure 3 shows localization of DPP9 near the plasma membrane of the cell leading edge during cell migration. Figure 2 shows that DPP9 is only localized near the plasma membrane and not " physically situated in or on the membrane (Fig. 2D)" |
complete | |||||
|
part_of |
GO:0005829 |
cytosol |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006508 |
proteolysis |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0008236 |
serine-type peptidase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016787 |
hydrolase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006508 |
proteolysis |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0008236 |
serine-type peptidase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004177 |
aminopeptidase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0008233 |
peptidase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005829 |
cytosol |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Zhang, H et al. (2015) Dipeptidyl peptidase 9 subcellular localization and a role in cell adhesion involving focal adhesion kinase and paxillin. Biochim. Biophys. Acta 1853 470-80 PubMed GONUTS page
- ↑ Tang, HK et al. (2011) Role of a propeller loop in the quaternary structure and enzymatic activity of prolyl dipeptidases DPP-IV and DPP9. FEBS Lett. 585 3409-14 PubMed GONUTS page
