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HUMAN:DPP6

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Species (Taxon ID) Homo sapiens (Human). (9606)
Gene Name(s) DPP6
Protein Name(s) Dipeptidyl aminopeptidase-like protein 6

DPPX Dipeptidyl aminopeptidase-related protein Dipeptidyl peptidase 6 Dipeptidyl peptidase IV-like protein Dipeptidyl peptidase VI DPP VI

External Links
UniProt P42658
EMBL M96859
M96860
AC006019
AC024239
AC024730
AC073336
CCDS CCDS75683.1
CCDS75684.1
PIR I54331
I68600
RefSeq NP_570629.2
UniGene Hs.490684
Hs.551097
Hs.669076
Hs.703229
PDB 1XFD
PDBsum 1XFD
ProteinModelPortal P42658
SMR P42658
BioGrid 108138
IntAct P42658
STRING 9606.ENSP00000367001
MEROPS S09.973
PhosphoSite P42658
DMDM 218512016
PaxDb P42658
PRIDE P42658
Ensembl ENST00000332007
ENST00000377770
GeneID 1804
KEGG hsa:1804
UCSC uc003wlk.3
uc003wlm.3
CTD 1804
GeneCards GC07P153584
H-InvDB HIX0020629
HGNC HGNC:3010
HPA HPA050509
MIM 126141
612956
neXtProt NX_P42658
Orphanet 2514
228140
PharmGKB PA27468
eggNOG COG1506
GeneTree ENSGT00760000119233
HOGENOM HOG000231875
HOVERGEN HBG105877
InParanoid P42658
OMA DLVENCT
PhylomeDB P42658
TreeFam TF313309
ChiTaRS DPP6
EvolutionaryTrace P42658
GeneWiki DPP6
GenomeRNAi 1804
NextBio 7349
PRO PR:P42658
Proteomes UP000005640
Bgee P42658
CleanEx HS_DPP6
ExpressionAtlas P42658
Genevestigator P42658
GO GO:0070062
GO:0016021
GO:0008239
GO:0008236
GO:0019228
GO:1901381
Gene3D 2.140.10.30
3.40.50.1820
InterPro IPR029058
IPR001375
IPR002469
Pfam PF00930
PF00326
SUPFAM SSF53474

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

part_of

GO:0005886

plasma membrane

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q9Z218

C

Seeded From UniProt

complete

enables

GO:0015459

potassium channel regulator activity

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q9Z218

F

Seeded From UniProt

complete

involved_in

GO:1901379

regulation of potassium ion transmembrane transport

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q9Z218

P

Seeded From UniProt

complete

involved_in

GO:0072659

protein localization to plasma membrane

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q9Z218

P

Seeded From UniProt

complete

involved_in

GO:1901379

regulation of potassium ion transmembrane transport

PMID:18364354[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

PMID:18364354[1]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0015459

potassium channel regulator activity

PMID:18364354[1]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

NOT|enables

GO:0008239

dipeptidyl-peptidase activity

PMID:8103397[2]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

part_of

GO:0008076

voltage-gated potassium channel complex

PMID:18364354[1]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0006508

proteolysis

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001375
InterPro:IPR002469

P

Seeded From UniProt

complete

enables

GO:0008236

serine-type peptidase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001375

F

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0812

C

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-1003
UniProtKB-SubCell:SL-0039

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 Soh, H & Goldstein, SA (2008) I SA channel complexes include four subunits each of DPP6 and Kv4.2. J. Biol. Chem. 283 15072-7 PubMed GONUTS page
  2. Yokotani, N et al. (1993) Non-conservation of a catalytic residue in a dipeptidyl aminopeptidase IV-related protein encoded by a gene on human chromosome 7. Hum. Mol. Genet. 2 1037-9 PubMed GONUTS page