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HUMAN:DBR1
Contents
Species (Taxon ID) | Homo sapiens (Human). (9606) | |
Gene Name(s) | DBR1 | |
Protein Name(s) | Lariat debranching enzyme | |
External Links | ||
UniProt | Q9UK59 | |
EMBL | AF180919 AK000116 BC009472 | |
CCDS | CCDS33863.1 | |
RefSeq | NP_057300.2 | |
UniGene | Hs.477700 | |
ProteinModelPortal | Q9UK59 | |
SMR | Q9UK59 | |
BioGrid | 119344 | |
IntAct | Q9UK59 | |
STRING | 9606.ENSP00000260803 | |
PhosphoSite | Q9UK59 | |
DMDM | 115311701 | |
MaxQB | Q9UK59 | |
PaxDb | Q9UK59 | |
PeptideAtlas | Q9UK59 | |
PRIDE | Q9UK59 | |
DNASU | 51163 | |
Ensembl | ENST00000260803 | |
GeneID | 51163 | |
KEGG | hsa:51163 | |
UCSC | uc003ert.3 uc003eru.3 | |
CTD | 51163 | |
GeneCards | GC03M137879 | |
HGNC | HGNC:15594 | |
HPA | HPA035365 | |
MIM | 607024 | |
neXtProt | NX_Q9UK59 | |
PharmGKB | PA27166 | |
eggNOG | NOG133819 | |
GeneTree | ENSGT00510000047481 | |
HOGENOM | HOG000216468 | |
HOVERGEN | HBG079917 | |
InParanoid | Q9UK59 | |
KO | K18328 | |
OMA | KVPCNFS | |
OrthoDB | EOG7BW0J7 | |
PhylomeDB | Q9UK59 | |
TreeFam | TF313221 | |
GeneWiki | DBR1 | |
GenomeRNAi | 51163 | |
NextBio | 54089 | |
PRO | PR:Q9UK59 | |
Proteomes | UP000005640 | |
Bgee | Q9UK59 | |
CleanEx | HS_DBR1 | |
ExpressionAtlas | Q9UK59 | |
Genevestigator | Q9UK59 | |
GO | GO:0005634 GO:0046872 GO:0044822 GO:0008419 GO:0000398 GO:0090502 GO:0000375 | |
Gene3D | 3.60.21.10 | |
InterPro | IPR004843 IPR007708 IPR029052 | |
Pfam | PF05011 PF00149 | |
SUPFAM | SSF56300 |
Annotations
Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
---|---|---|---|---|---|---|---|---|---|---|
enables |
GO:0003723 |
RNA binding |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0008419 |
RNA lariat debranching enzyme activity |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
part_of |
GO:0005634 |
nucleus |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0000375 |
RNA splicing, via transesterification reactions |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0008419 |
RNA lariat debranching enzyme activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:1931520 |
F |
Seeded From UniProt |
complete | ||
part_of |
GO:0005634 |
nucleus |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000304155 |
C |
Seeded From UniProt |
complete | ||
involved_in |
GO:0000398 |
mRNA splicing, via spliceosome |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:1931520 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0005654 |
nucleoplasm |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0090502 |
RNA phosphodiester bond hydrolysis, endonucleolytic |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0008419 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0090502 |
RNA phosphodiester bond hydrolysis, endonucleolytic |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0008419 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0090502 |
RNA phosphodiester bond hydrolysis, endonucleolytic |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0008419 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0008419 |
RNA lariat debranching enzyme activity |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q923B1 |
F |
Seeded From UniProt |
complete | ||
involved_in |
GO:0000398 |
mRNA splicing, via spliceosome |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q923B1 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0006397 |
mRNA processing |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0016787 |
hydrolase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0016788 |
hydrolase activity, acting on ester bonds |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0016787 |
hydrolase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0046872 |
metal ion binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
part_of |
GO:0005634 |
nucleus |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0006397 |
mRNA processing |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Castello, A et al. (2012) Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. Cell 149 1393-406 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 Kim, JW et al. (2000) Human RNA lariat debranching enzyme cDNA complements the phenotypes of Saccharomyces cerevisiae dbr1 and Schizosaccharomyces pombe dbr1 mutants. Nucleic Acids Res. 28 3666-73 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
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