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HUMAN:CSTN1

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Species (Taxon ID) Homo sapiens (Human). (9606)
Gene Name(s) CLSTN1 (synonyms: CS1, KIAA0911)
Protein Name(s) Calsyntenin-1

Alcadein-alpha Alc-alpha Alzheimer-related cadherin-like protein Non-classical cadherin XB31alpha Soluble Alc-alpha SAlc-alpha CTF1-alpha C-terminal fragment 1-alpha

External Links
UniProt O94985
EMBL AF438482
AY753301
AB020718
AK289798
AL691449
AL357140
AL691449
AL357140
AL357140
AL691449
AL357140
AL691449
BC033902
CCDS CCDS105.1
CCDS30580.1
RefSeq NP_001009566.1
NP_055759.3
UniGene Hs.29665
ProteinModelPortal O94985
BioGrid 116550
IntAct O94985
MINT MINT-4544144
STRING 9606.ENSP00000366513
PhosphoSite O94985
MaxQB O94985
PaxDb O94985
PRIDE O94985
DNASU 22883
Ensembl ENST00000361311
ENST00000377298
GeneID 22883
KEGG hsa:22883
UCSC uc001aqh.3
uc001aqi.3
CTD 22883
GeneCards GC01M009789
HGNC HGNC:17447
HPA HPA012412
MIM 611321
neXtProt NX_O94985
PharmGKB PA38238
eggNOG NOG246161
GeneTree ENSGT00390000010858
HOGENOM HOG000037537
HOVERGEN HBG051146
InParanoid O94985
OMA NWTVGLP
OrthoDB EOG7SFHVX
PhylomeDB O94985
TreeFam TF315946
ChiTaRS CLSTN1
GeneWiki CLSTN1
GenomeRNAi 22883
NextBio 43465
PMAP-CutDB O94985
PRO PR:O94985
Proteomes UP000005640
Bgee O94985
CleanEx HS_CLSTN1
ExpressionAtlas O94985
Genevestigator O94985
GO GO:0030054
GO:0042995
GO:0005789
GO:0070062
GO:0000139
GO:0016021
GO:0005634
GO:0045211
GO:0001540
GO:0005509
GO:0019894
GO:0042988
GO:0007155
GO:0007156
Gene3D 2.60.120.200
2.60.40.60
InterPro IPR002126
IPR015919
IPR026914
IPR013320
PANTHER PTHR14139
Pfam PF00028
PRINTS PR00205
SMART SM00112
SUPFAM SSF49313
SSF49899
PROSITE PS50268

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

enables

GO:0042988

X11-like protein binding

PMID:12972431[1]

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:O00213

F

Seeded From UniProt

complete

enables

GO:0042988

X11-like protein binding

PMID:17332754[2]

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:O00213

F

Seeded From UniProt

complete

enables

GO:0019894

kinesin binding

PMID:17332754[2]

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:Q07866

F

Seeded From UniProt

complete

enables

GO:0001540

amyloid-beta binding

PMID:17332754[2]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0051965

positive regulation of synapse assembly

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1929895
MGI:MGI:1929897
MGI:MGI:2178323
PANTHER:PTN001020450

P

Seeded From UniProt

complete

involved_in

GO:0050806

positive regulation of synaptic transmission

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1929895
MGI:MGI:1929897
MGI:MGI:2178323
PANTHER:PTN001020450

P

Seeded From UniProt

complete

part_of

GO:0045211

postsynaptic membrane

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1929895
MGI:MGI:1929897
MGI:MGI:2178323
PANTHER:PTN001020450
RGD:621151
RGD:621153

C

Seeded From UniProt

complete

part_of

GO:0009986

cell surface

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1929895
MGI:MGI:1929897
MGI:MGI:2178323
PANTHER:PTN001020450

C

Seeded From UniProt

complete

part_of

GO:0099065

integral component of spine apparatus membrane

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q6Q0N0
ensembl:ENSRNOP00000047223

C

Seeded From UniProt

complete

part_of

GO:0099061

integral component of postsynaptic density membrane

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q6Q0N0
ensembl:ENSRNOP00000047223

C

Seeded From UniProt

complete

part_of

GO:0098982

GABA-ergic synapse

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q6Q0N0
ensembl:ENSRNOP00000047223

C

Seeded From UniProt

complete

part_of

GO:0098978

glutamatergic synapse

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q6Q0N0
ensembl:ENSRNOP00000047223

C

Seeded From UniProt

complete

involved_in

GO:0099003

vesicle-mediated transport in synapse

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9EPL2
ensembl:ENSMUSP00000036962

P

Seeded From UniProt

complete

part_of

GO:0098978

glutamatergic synapse

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9EPL2
ensembl:ENSMUSP00000036962

C

Seeded From UniProt

complete

involved_in

GO:0098969

neurotransmitter receptor transport to postsynaptic membrane

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9EPL2
ensembl:ENSMUSP00000036962

P

Seeded From UniProt

complete

part_of

GO:0098845

postsynaptic endosome

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9EPL2
ensembl:ENSMUSP00000036962

C

Seeded From UniProt

complete

involved_in

GO:0090128

regulation of synapse maturation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9EPL2
ensembl:ENSMUSP00000036962

P

Seeded From UniProt

complete

involved_in

GO:0051965

positive regulation of synapse assembly

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9EPL2
ensembl:ENSMUSP00000036962

P

Seeded From UniProt

complete

involved_in

GO:0050806

positive regulation of synaptic transmission

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9EPL2
ensembl:ENSMUSP00000036962

P

Seeded From UniProt

complete

part_of

GO:0045211

postsynaptic membrane

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9EPL2
ensembl:ENSMUSP00000036962

C

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9EPL2
ensembl:ENSMUSP00000036962

C

Seeded From UniProt

complete

part_of

GO:0014069

postsynaptic density

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9EPL2
ensembl:ENSMUSP00000036962

C

Seeded From UniProt

complete

part_of

GO:0009986

cell surface

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9EPL2
ensembl:ENSMUSP00000036962

C

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9EPL2
ensembl:ENSMUSP00000036962

C

Seeded From UniProt

complete

involved_in

GO:0001558

regulation of cell growth

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9EPL2
ensembl:ENSMUSP00000036962

P

Seeded From UniProt

complete

enables

GO:0005509

calcium ion binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR002126
InterPro:IPR015919
InterPro:IPR026914

F

Seeded From UniProt

complete

involved_in

GO:0007156

homophilic cell adhesion via plasma membrane adhesion molecules

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR002126

P

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR002126
InterPro:IPR015919

C

Seeded From UniProt

complete

involved_in

GO:0007155

cell adhesion

PMID:17332754[2]

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0030054

cell junction

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0965

C

Seeded From UniProt

complete

part_of

GO:0045202

synapse

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0770

C

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0812

C

Seeded From UniProt

complete

part_of

GO:0005783

endoplasmic reticulum

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0256

C

Seeded From UniProt

complete

part_of

GO:0042995

cell projection

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0966
UniProtKB-SubCell:SL-0280

C

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-1003

C

Seeded From UniProt

complete

part_of

GO:0045211

postsynaptic membrane

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0628
UniProtKB-SubCell:SL-0219

C

Seeded From UniProt

complete

involved_in

GO:0007155

cell adhesion

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0130

P

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0539
UniProtKB-SubCell:SL-0191

C

Seeded From UniProt

complete

part_of

GO:0005794

Golgi apparatus

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0333

C

Seeded From UniProt

complete

part_of

GO:0000139

Golgi membrane

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0134

C

Seeded From UniProt

complete

part_of

GO:0005789

endoplasmic reticulum membrane

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0097

C

Seeded From UniProt

complete

edit table

Notes

References

See Help:References for how to manage references in GONUTS.

  1. ↑ Araki, Y et al. (2003) Novel cadherin-related membrane proteins, Alcadeins, enhance the X11-like protein-mediated stabilization of amyloid beta-protein precursor metabolism. J. Biol. Chem. 278 49448-58 PubMed GONUTS page
  2. ↑ 2.0 2.1 2.2 2.3 Araki, Y et al. (2007) The novel cargo Alcadein induces vesicle association of kinesin-1 motor components and activates axonal transport. EMBO J. 26 1475-86 PubMed GONUTS page
  3. ↑ 3.0 3.1 3.2 3.3 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
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