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HUMAN:CNTRB
Contents
Species (Taxon ID) | Homo sapiens (Human). (9606) | |
Gene Name(s) | CNTROB (synonyms: LIP8) | |
Protein Name(s) | Centrobin
Centrosomal BRCA2-interacting protein LYST-interacting protein 8 | |
External Links | ||
UniProt | Q8N137 | |
EMBL | AY160226 AY160227 AF331638 AL137669 AL833907 AC104581 BC014055 BC021134 AK074847 AF141344 | |
CCDS | CCDS11126.1 CCDS32557.1 | |
RefSeq | NP_001032221.1 NP_444279.2 XP_005256494.1 | |
UniGene | Hs.348012 | |
ProteinModelPortal | Q8N137 | |
BioGrid | 125533 | |
IntAct | Q8N137 | |
MINT | MINT-2878302 | |
STRING | 9606.ENSP00000369614 | |
PhosphoSite | Q8N137 | |
DMDM | 74728485 | |
MaxQB | Q8N137 | |
PaxDb | Q8N137 | |
PRIDE | Q8N137 | |
DNASU | 116840 | |
Ensembl | ENST00000380262 ENST00000563694 ENST00000565740 | |
GeneID | 116840 | |
KEGG | hsa:116840 | |
UCSC | uc002gjp.3 uc002gjq.3 uc002gjr.3 | |
CTD | 116840 | |
GeneCards | GC17P007835 | |
HGNC | HGNC:29616 | |
HPA | HPA023319 HPA023320 HPA023321 HPA023325 | |
MIM | 611425 | |
neXtProt | NX_Q8N137 | |
PharmGKB | PA143485436 | |
eggNOG | NOG128239 | |
GeneTree | ENSGT00610000086191 | |
HOVERGEN | HBG081290 | |
InParanoid | Q8N137 | |
KO | K16468 | |
OMA | AMLQAHW | |
OrthoDB | EOG7KH9J6 | |
PhylomeDB | Q8N137 | |
TreeFam | TF337444 | |
ChiTaRS | CNTROB | |
GeneWiki | CNTROB | |
GenomeRNAi | 116840 | |
NextBio | 80002 | |
PRO | PR:Q8N137 | |
Proteomes | UP000005640 | |
Bgee | Q8N137 | |
CleanEx | HS_CNTROB | |
ExpressionAtlas | Q8N137 | |
Genevestigator | Q8N137 | |
GO | GO:0005814 GO:0005813 GO:0005737 GO:0019904 GO:0007099 GO:0051299 GO:1902410 |
Annotations
Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
---|---|---|---|---|---|---|---|---|---|---|
GO:0007099 |
positive regulation of centriole replication |
ECO:0000315 |
P |
Figure 3 |
complete | |||||
GO:0005813 |
protein localization to centrosome |
ECO:0000315 |
P |
Figure 5 |
complete | |||||
part_of |
GO:0005814 |
centriole |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005813 |
centrosome |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0007099 |
centriole replication |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0051299 |
centrosome separation |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0007099 |
centriole replication |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0005814 |
centriole |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:1902410 |
mitotic cytokinetic process |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0019904 |
protein domain specific binding |
ECO:0000353 |
physical interaction evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
part_of |
GO:0005813 |
centrosome |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:1902410 |
mitotic cytokinetic process |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN002438084 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0051299 |
centrosome separation |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN002438084 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0007099 |
centriole replication |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN002438084 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0005814 |
centriole |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0035295 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0005813 |
centrosome |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN002438084 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0005829 |
cytosol |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005813 |
centrosome |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0007099 |
centriole replication |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:1902017 |
regulation of cilium assembly |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0005737 |
cytoplasm |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005856 |
cytoskeleton |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0007049 |
cell cycle |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0051301 |
cell division |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0005814 |
centriole |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 Gudi, R et al. (2011) Centrobin-tubulin interaction is required for centriole elongation and stability. J. Cell Biol. 193 711-25 PubMed GONUTS page
- ↑ Chang, CW et al. (2016) CEP295 interacts with microtubules and is required for centriole elongation. J. Cell. Sci. 129 2501-13 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 Zou, C et al. (2005) Centrobin: a novel daughter centriole-associated protein that is required for centriole duplication. J. Cell Biol. 171 437-45 PubMed GONUTS page
- ↑ Tchernev, VT et al. (2002) The Chediak-Higashi protein interacts with SNARE complex and signal transduction proteins. Mol. Med. 8 56-64 PubMed GONUTS page
- ↑ Jakobsen, L et al. (2011) Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods. EMBO J. 30 1520-35 PubMed GONUTS page
- ↑ 6.0 6.1 6.2 6.3 6.4 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page