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HUMAN:CNEP1
Contents
| Species (Taxon ID) | Homo sapiens (Human). (9606) | |
| Gene Name(s) | CTDNEP1 (synonyms: DULLARD) | |
| Protein Name(s) | CTD nuclear envelope phosphatase 1
Serine/threonine-protein phosphatase dullard | |
| External Links | ||
| UniProt | O95476 | |
| EMBL | AJ011916 AY364239 AC003688 AC120057 CH471108 CH471108 CH471108 BC009295 | |
| CCDS | CCDS11093.1 | |
| RefSeq | NP_001137247.1 NP_056158.2 | |
| UniGene | Hs.513913 | |
| ProteinModelPortal | O95476 | |
| SMR | O95476 | |
| BioGrid | 116972 | |
| IntAct | O95476 | |
| STRING | 9606.ENSP00000321732 | |
| DEPOD | O95476 | |
| PhosphoSite | O95476 | |
| MaxQB | O95476 | |
| PaxDb | O95476 | |
| PRIDE | O95476 | |
| DNASU | 23399 | |
| Ensembl | ENST00000318988 ENST00000573600 ENST00000574205 ENST00000574322 | |
| GeneID | 23399 | |
| KEGG | hsa:23399 | |
| UCSC | uc002gfd.2 | |
| CTD | 23399 | |
| GeneCards | GC17M007147 | |
| HGNC | HGNC:19085 | |
| HPA | HPA037439 | |
| MIM | 610684 | |
| neXtProt | NX_O95476 | |
| PharmGKB | PA134937999 | |
| eggNOG | COG5190 | |
| GeneTree | ENSGT00550000075053 | |
| HOGENOM | HOG000236379 | |
| HOVERGEN | HBG098153 | |
| InParanoid | O95476 | |
| KO | K17617 | |
| OMA | RYFRQHC | |
| PhylomeDB | O95476 | |
| TreeFam | TF313962 | |
| Reactome | REACT_200828 | |
| SABIO-RK | O95476 | |
| SignaLink | O95476 | |
| ChiTaRS | CTDNEP1 | |
| GenomeRNAi | 23399 | |
| NextBio | 45549 | |
| PRO | PR:O95476 | |
| Proteomes | UP000005640 | |
| Bgee | O95476 | |
| CleanEx | HS_DULLARD | |
| ExpressionAtlas | O95476 | |
| Genevestigator | O95476 | |
| GO | GO:0005737 GO:0005789 GO:0016021 GO:0071595 GO:0005635 GO:0031965 GO:0004722 GO:0007276 GO:0007498 GO:0006998 GO:0090263 GO:0010867 GO:0006470 GO:0034504 | |
| Gene3D | 3.40.50.1000 | |
| InterPro | IPR011948 IPR023214 IPR004274 | |
| Pfam | PF03031 | |
| SMART | SM00577 | |
| SUPFAM | SSF56784 | |
| TIGRFAMs | TIGR02251 | |
| PROSITE | PS50969 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
part_of |
GO:0071595 |
Nem1-Spo7 phosphatase complex |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0034504 |
protein localization to nucleus |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0031965 |
nuclear membrane |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0010867 |
positive regulation of triglyceride biosynthetic process |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
P |
Seeded From UniProt |
Missing: with/from | |||
|
involved_in |
GO:0006998 |
nuclear envelope organization |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006470 |
protein dephosphorylation |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006470 |
protein dephosphorylation |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005789 |
endoplasmic reticulum membrane |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005635 |
nuclear envelope |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004722 |
protein serine/threonine phosphatase activity |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004721 |
phosphoprotein phosphatase activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:1196405 |
F |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005811 |
lipid droplet |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0090263 |
positive regulation of canonical Wnt signaling pathway |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q3TP92 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0007498 |
mesoderm development |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q3TP92 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0007276 |
gamete generation |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q3TP92 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q3TP92 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q3TP92 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0016791 |
phosphatase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004721 |
phosphoprotein phosphatase activity |
ECO:0000501 |
evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0007077 |
mitotic nuclear envelope disassembly |
Reactome:R-HSA-2980766 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005635 |
nuclear envelope |
Reactome:R-HSA-4419948 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0004722 |
protein serine/threonine phosphatase activity |
Reactome:R-HSA-4419948 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0004721 |
phosphoprotein phosphatase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016020 |
membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005783 |
endoplasmic reticulum |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016787 |
hydrolase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0031965 |
nuclear membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005789 |
endoplasmic reticulum membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 Han, S et al. (2012) Nuclear envelope phosphatase 1-regulatory subunit 1 (formerly TMEM188) is the metazoan Spo7p ortholog and functions in the lipin activation pathway. J. Biol. Chem. 287 3123-37 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 2.4 Kim, Y et al. (2007) A conserved phosphatase cascade that regulates nuclear membrane biogenesis. Proc. Natl. Acad. Sci. U.S.A. 104 6596-601 PubMed GONUTS page
- ↑ Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
e
m
n
p
- GO:0016791 ! phosphatase activity
- GO:0004721 ! phosphoprotein phosphatase activity
- GO:0090263 ! positive regulation of canonical Wnt signaling pathway
- GO:0010867 ! positive regulation of triglyceride biosynthetic process
- Primates
- GO:0006470 ! protein dephosphorylation
- GO:0034504 ! protein localization to nucleus
- GO:0004722 ! protein serine/threonine phosphatase activity
