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HUMAN:B4DJU0

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Species (Taxon ID) Homo sapiens (Human). (9606)
Gene Name(s) LAYN
Protein Name(s) Layilin

cDNA FLJ50977, highly similar to Homo sapiens layilin, mRNA

External Links
UniProt B4DJU0
EMBL AP002008
AK296231
RefSeq NP_001245319.1
NP_001245320.1
NP_849156.1
UniGene Hs.503831
Ensembl ENST00000436913
GeneID 143903
KEGG hsa:143903
UCSC uc010rwg.2
CTD 143903
HGNC HGNC:29471
HOGENOM HOG000069977
HOVERGEN HBG050945
KO K10077
GenomeRNAi 143903
NextBio 84809

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

part_of

GO:0005925

focal adhesion

PMID:21423176[1]

ECO:0007005

high throughput direct assay evidence used in manual assertion

C

part_of:(CL:0000057)

Seeded From UniProt

complete

part_of

GO:0009986

cell surface

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q9Z209

C

Seeded From UniProt

complete

NOT|part_of

GO:0005925

focal adhesion

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q9Z209

C

Seeded From UniProt

complete

enables

GO:0005540

hyaluronic acid binding

PMID:11294894[2]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

part_of

GO:0001726

ruffle

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q9Z209

C

Seeded From UniProt

complete

enables

GO:0005540

hyaluronic acid binding

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002686033
UniProtKB:Q6UX15

F

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472
UniProtKB-SubCell:SL-0162

C

Seeded From UniProt

complete

enables

GO:0030246

carbohydrate binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0430

F

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0812

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Kuo, JC et al. (2011) Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation. Nat. Cell Biol. 13 383-93 PubMed GONUTS page
  2. Bono, P et al. (2001) Layilin, a novel integral membrane protein, is a hyaluronan receptor. Mol. Biol. Cell 12 891-900 PubMed GONUTS page
  3. Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page