HUMAN:B2R9L7

Species (Taxon ID)	Homo sapiens (Human). (9606)
Gene Name(s)	OXTR (ECO:0000313 with EMBL:AAI37444.1)
Protein Name(s)	Oxytocin receptor (ECO:0000256 with RuleBase:RU046427)
External Links
UniProt	B2R9L7
EMBL	BC137443 AK313830 CH471055
RefSeq	NP_000907.2
UniGene	Hs.2820
SMR	B2R9L7
GeneID	5021
KEGG	hsa:5021
CTD	5021
PharmGKB	PA32858
HOVERGEN	HBG105710
KO	K04229
OMA	GPPRRNE
PhylomeDB	B2R9L7
GenomeRNAi	5021
NextBio	19332
GO	GO:0016324 GO:0005913 GO:0016021 GO:0005902 GO:0004990 GO:0017046 GO:0005000 GO:0048565 GO:0042755 GO:0070371 GO:0007565 GO:0007507 GO:0042711 GO:0060137 GO:0007613 GO:0060455 GO:0045777 GO:0007204 GO:0010701 GO:0060406 GO:0051965 GO:0032230 GO:0051968 GO:0070474 GO:0001975 GO:0034059 GO:0042220 GO:0034097 GO:0042493 GO:0032355 GO:0043434 GO:0032570 GO:0030431 GO:0035176 GO:0042713 GO:0001967 GO:0021537
InterPro	IPR000276 IPR017452 IPR002062 IPR001817
Pfam	PF00001
PRINTS	PR00237 PR00665 PR00896
PROSITE	PS00237 PS50262

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
involved_in	GO:0070474	positive regulation of uterine smooth muscle contraction	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P70536 ensembl:ENSRNOP00000007724	P		Seeded From UniProt	complete
involved_in	GO:0070371	ERK1 and ERK2 cascade	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P70536 ensembl:ENSRNOP00000007724	P		Seeded From UniProt	complete
involved_in	GO:0060455	negative regulation of gastric acid secretion	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P70536 ensembl:ENSRNOP00000007724	P		Seeded From UniProt	complete
involved_in	GO:0060406	positive regulation of penile erection	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P70536 ensembl:ENSRNOP00000007724	P		Seeded From UniProt	complete
involved_in	GO:0060137	maternal process involved in parturition	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P70536 ensembl:ENSRNOP00000007724	P		Seeded From UniProt	complete
involved_in	GO:0051968	positive regulation of synaptic transmission, glutamatergic	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P70536 ensembl:ENSRNOP00000007724	P		Seeded From UniProt	complete
involved_in	GO:0051965	positive regulation of synapse assembly	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P70536 ensembl:ENSRNOP00000007724	P		Seeded From UniProt	complete
involved_in	GO:0048565	digestive tract development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P70536 ensembl:ENSRNOP00000007724	P		Seeded From UniProt	complete
involved_in	GO:0048545	response to steroid hormone	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P70536 ensembl:ENSRNOP00000007724	P		Seeded From UniProt	complete
involved_in	GO:0044849	estrous cycle	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P70536 ensembl:ENSRNOP00000007724	P		Seeded From UniProt	complete
involved_in	GO:0044058	regulation of digestive system process	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P70536 ensembl:ENSRNOP00000007724	P		Seeded From UniProt	complete
involved_in	GO:0043434	response to peptide hormone	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P70536 ensembl:ENSRNOP00000007724	P		Seeded From UniProt	complete
involved_in	GO:0042755	eating behavior	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P70536 ensembl:ENSRNOP00000007724	P		Seeded From UniProt	complete
involved_in	GO:0042713	sperm ejaculation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P70536 ensembl:ENSRNOP00000007724	P		Seeded From UniProt	complete
involved_in	GO:0042711	maternal behavior	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P70536 ensembl:ENSRNOP00000007724	P		Seeded From UniProt	complete
involved_in	GO:0042493	response to drug	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P70536 ensembl:ENSRNOP00000007724	P		Seeded From UniProt	complete
involved_in	GO:0042220	response to cocaine	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P70536 ensembl:ENSRNOP00000007724	P		Seeded From UniProt	complete
involved_in	GO:0035176	social behavior	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P70536 ensembl:ENSRNOP00000007724	P		Seeded From UniProt	complete
involved_in	GO:0034097	response to cytokine	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P70536 ensembl:ENSRNOP00000007724	P		Seeded From UniProt	complete
involved_in	GO:0034059	response to anoxia	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P70536 ensembl:ENSRNOP00000007724	P		Seeded From UniProt	complete
involved_in	GO:0032570	response to progesterone	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P70536 ensembl:ENSRNOP00000007724	P		Seeded From UniProt	complete
involved_in	GO:0032355	response to estradiol	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P70536 ensembl:ENSRNOP00000007724	P		Seeded From UniProt	complete
involved_in	GO:0032230	positive regulation of synaptic transmission, GABAergic	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P70536 ensembl:ENSRNOP00000007724	P		Seeded From UniProt	complete
involved_in	GO:0030431	sleep	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P70536 ensembl:ENSRNOP00000007724	P		Seeded From UniProt	complete
involved_in	GO:0021537	telencephalon development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P70536 ensembl:ENSRNOP00000007724	P		Seeded From UniProt	complete
enables	GO:0017046	peptide hormone binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P70536 ensembl:ENSRNOP00000007724	F		Seeded From UniProt	complete
part_of	GO:0016324	apical plasma membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P70536 ensembl:ENSRNOP00000007724	C		Seeded From UniProt	complete
involved_in	GO:0014070	response to organic cyclic compound	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P70536 ensembl:ENSRNOP00000007724	P		Seeded From UniProt	complete
involved_in	GO:0010701	positive regulation of norepinephrine secretion	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P70536 ensembl:ENSRNOP00000007724	P		Seeded From UniProt	complete
involved_in	GO:0007613	memory	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P70536 ensembl:ENSRNOP00000007724	P		Seeded From UniProt	complete
involved_in	GO:0007565	female pregnancy	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P70536 ensembl:ENSRNOP00000007724	P		Seeded From UniProt	complete
involved_in	GO:0007507	heart development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P70536 ensembl:ENSRNOP00000007724	P		Seeded From UniProt	complete
involved_in	GO:0007204	positive regulation of cytosolic calcium ion concentration	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P70536 ensembl:ENSRNOP00000007724	P		Seeded From UniProt	complete
involved_in	GO:0007186	G protein-coupled receptor signaling pathway	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P70536 ensembl:ENSRNOP00000007724	P		Seeded From UniProt	complete
part_of	GO:0005913	cell-cell adherens junction	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P70536 ensembl:ENSRNOP00000007724	C		Seeded From UniProt	complete
part_of	GO:0005902	microvillus	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P70536 ensembl:ENSRNOP00000007724	C		Seeded From UniProt	complete
enables	GO:0004990	oxytocin receptor activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P70536 ensembl:ENSRNOP00000007724	F		Seeded From UniProt	complete
involved_in	GO:0001975	response to amphetamine	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P70536 ensembl:ENSRNOP00000007724	P		Seeded From UniProt	complete
involved_in	GO:0001967	suckling behavior	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P70536 ensembl:ENSRNOP00000007724	P		Seeded From UniProt	complete
involved_in	GO:0120162	positive regulation of cold-induced thermogenesis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P97926 ensembl:ENSMUSP00000051132	P		Seeded From UniProt	complete
involved_in	GO:0045777	positive regulation of blood pressure	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P97926 ensembl:ENSMUSP00000051132	P		Seeded From UniProt	complete
enables	GO:0004930	G protein-coupled receptor activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000276	F		Seeded From UniProt	complete
enables	GO:0004990	oxytocin receptor activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR002062	F		Seeded From UniProt	complete
enables	GO:0005000	vasopressin receptor activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001817	F		Seeded From UniProt	complete
involved_in	GO:0007186	G protein-coupled receptor signaling pathway	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000276 InterPro:IPR001817 InterPro:IPR002062	P		Seeded From UniProt	complete
part_of	GO:0016021	integral component of membrane	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000276 InterPro:IPR001817 InterPro:IPR002062 InterPro:IPR017452	C		Seeded From UniProt	complete
enables	GO:0004930	G protein-coupled receptor activity	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0297	F		Seeded From UniProt	complete
involved_in	GO:0007186	G protein-coupled receptor signaling pathway	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0297	P		Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0472	C		Seeded From UniProt	complete
involved_in	GO:0007165	signal transduction	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0807	P		Seeded From UniProt	complete
part_of	GO:0016021	integral component of membrane	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0812	C		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000040	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-SubCell:SL-0039	C		Seeded From UniProt	complete
enables	GO:0004990	oxytocin receptor activity	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000046427	F		Seeded From UniProt	complete
part_of	GO:0016021	integral component of membrane	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000046427	C		Seeded From UniProt	complete
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References

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