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HUMAN:ATCAY

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Species (Taxon ID) Homo sapiens (Human). (9606)
Gene Name(s) ATCAY (synonyms: KIAA1872)
Protein Name(s) Caytaxin

Ataxia cayman type protein BNIP-2-homology BNIP-H

External Links
UniProt Q86WG3
EMBL AY220297
AB058775
AK092309
BC008736
BC026217
CCDS CCDS45923.1
RefSeq NP_149053.1
UniGene Hs.418055
ProteinModelPortal Q86WG3
BioGrid 124463
IntAct Q86WG3
STRING 9606.ENSP00000390941
PhosphoSite Q86WG3
DMDM 38257451
MaxQB Q86WG3
PaxDb Q86WG3
PRIDE Q86WG3
DNASU 85300
Ensembl ENST00000450849
ENST00000600960
GeneID 85300
KEGG hsa:85300
UCSC uc002lyy.4
CTD 85300
GeneCards GC19P003880
HGNC HGNC:779
HPA HPA017755
MIM 601238
608179
neXtProt NX_Q86WG3
Orphanet 94122
PharmGKB PA25080
eggNOG NOG146204
GeneTree ENSGT00420000029688
HOGENOM HOG000230952
HOVERGEN HBG054692
InParanoid Q86WG3
KO K18450
OMA MRVVTHG
PhylomeDB Q86WG3
TreeFam TF324164
ChiTaRS ATCAY
GenomeRNAi 85300
NextBio 75779
PRO PR:Q86WG3
Proteomes UP000005640
Bgee Q86WG3
CleanEx HS_ATCAY
ExpressionAtlas Q86WG3
Genevestigator Q86WG3
GO GO:0030424
GO:0030054
GO:0005737
GO:0030425
GO:0031966
GO:0043005
GO:0045202
GO:0019894
GO:0006915
GO:0048311
GO:2000212
GO:0031175
GO:0032880
GO:0006810
Gene3D 3.40.525.10
InterPro IPR022181
IPR001251
Pfam PF12496
PF13716
SUPFAM SSF52087
PROSITE PS50191

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:2000212

negative regulation of glutamate metabolic process

PMID:16899818[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0048311

mitochondrion distribution

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q1M168

P

Seeded From UniProt

complete

part_of

GO:0045202

synapse

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q1M168

C

Seeded From UniProt

complete

part_of

GO:0043005

neuron projection

PMID:16899818[1]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0032880

regulation of protein localization

PMID:16899818[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0031966

mitochondrial membrane

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q8BHE3

C

Seeded From UniProt

complete

involved_in

GO:0031175

neuron projection development

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q8BHE3

P

Seeded From UniProt

complete

part_of

GO:0030425

dendrite

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q1M168

C

Seeded From UniProt

complete

part_of

GO:0030424

axon

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q1M168

C

Seeded From UniProt

complete

enables

GO:0019894

kinesin binding

PMID:19861499[2]

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:Q07866

F

Seeded From UniProt

complete

NOT|colocalizes_with

GO:0005739

mitochondrion

PMID:16899818[1]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

PMID:16899818[1]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0006915

apoptotic process

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000251507
UniProtKB:Q12982
UniProtKB:Q7Z465

P

Seeded From UniProt

complete

involved_in

GO:0006798

polyphosphate catabolic process

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001087311
SGD:S000001244

P

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001087311
SGD:S000001244
UniProtKB:Q12982
UniProtKB:Q86WG3

C

Seeded From UniProt

complete

enables

GO:0004309

exopolyphosphatase activity

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001087311
SGD:S000001244

F

Seeded From UniProt

complete

part_of

GO:0048471

perinuclear region of cytoplasm

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q1M168
ensembl:ENSRNOP00000045560

C

Seeded From UniProt

complete

involved_in

GO:0048311

mitochondrion distribution

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q1M168
ensembl:ENSRNOP00000045560

P

Seeded From UniProt

complete

part_of

GO:0045202

synapse

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q1M168
ensembl:ENSRNOP00000045560

C

Seeded From UniProt

complete

part_of

GO:0044306

neuron projection terminus

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q1M168
ensembl:ENSRNOP00000045560

C

Seeded From UniProt

complete

involved_in

GO:0031175

neuron projection development

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q1M168
ensembl:ENSRNOP00000045560

P

Seeded From UniProt

complete

part_of

GO:0030425

dendrite

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q1M168
ensembl:ENSRNOP00000045560

C

Seeded From UniProt

complete

part_of

GO:0030424

axon

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q1M168
ensembl:ENSRNOP00000045560

C

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q1M168
ensembl:ENSRNOP00000045560

C

Seeded From UniProt

complete

part_of

GO:0043005

neuron projection

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q8BHE3
ensembl:ENSMUSP00000036721

C

Seeded From UniProt

complete

involved_in

GO:0031175

neuron projection development

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q8BHE3
ensembl:ENSMUSP00000036721

P

Seeded From UniProt

complete

part_of

GO:0042995

cell projection

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0966

C

Seeded From UniProt

complete

part_of

GO:0030054

cell junction

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0965

C

Seeded From UniProt

complete

part_of

GO:0045202

synapse

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0770
UniProtKB-SubCell:SL-0258

C

Seeded From UniProt

complete

involved_in

GO:0007399

nervous system development

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0524

P

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

part_of

GO:0030425

dendrite

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0283

C

Seeded From UniProt

complete

part_of

GO:0030424

axon

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0279

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 1.4 Buschdorf, JP et al. (2006) Brain-specific BNIP-2-homology protein Caytaxin relocalises glutaminase to neurite terminals and reduces glutamate levels. J. Cell. Sci. 119 3337-50 PubMed GONUTS page
  2. Aoyama, T et al. (2009) Cayman ataxia protein caytaxin is transported by kinesin along neurites through binding to kinesin light chains. J. Cell. Sci. 122 4177-85 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page