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HUMAN:ARID2
Contents
| Species (Taxon ID) | Homo sapiens (Human). (9606) | |
| Gene Name(s) | ARID2 (synonyms: KIAA1557) | |
| Protein Name(s) | AT-rich interactive domain-containing protein 2
ARID domain-containing protein 2 BRG1-associated factor 200 BAF200 Zinc finger protein with activation potential Zipzap/p200 | |
| External Links | ||
| UniProt | Q68CP9 | |
| EMBL | DQ096628 AY727870 AL832200 BX537879 CR749833 AK027718 AK127872 BC090062 AB046777 | |
| CCDS | CCDS31783.1 | |
| RefSeq | NP_001334768.1 NP_689854.2 | |
| UniGene | Hs.317304 | |
| ProteinModelPortal | Q68CP9 | |
| BioGrid | 128219 | |
| DIP | DIP-33391N | |
| IntAct | Q68CP9 | |
| STRING | 9606.ENSP00000335044 | |
| iPTMnet | Q68CP9 | |
| PhosphoSitePlus | Q68CP9 | |
| BioMuta | ARID2 | |
| DMDM | 73921721 | |
| EPD | Q68CP9 | |
| MaxQB | Q68CP9 | |
| PaxDb | Q68CP9 | |
| PeptideAtlas | Q68CP9 | |
| PRIDE | Q68CP9 | |
| DNASU | 196528 | |
| Ensembl | ENST00000334344 | |
| GeneID | 196528 | |
| KEGG | hsa:196528 | |
| UCSC | uc001ros.2 | |
| CTD | 196528 | |
| DisGeNET | 196528 | |
| GeneCards | ARID2 | |
| HGNC | HGNC:18037 | |
| HPA | HPA063044 | |
| MIM | 609539 | |
| neXtProt | NX_Q68CP9 | |
| OpenTargets | ENSG00000189079 | |
| PharmGKB | PA134916396 | |
| eggNOG | KOG2312 KOG2744 ENOG410XT3H | |
| GeneTree | ENSGT00390000016138 | |
| HOVERGEN | HBG068777 | |
| InParanoid | Q68CP9 | |
| KO | K11765 | |
| OMA | LKQYYLR | |
| OrthoDB | EOG091G169Y | |
| PhylomeDB | Q68CP9 | |
| TreeFam | TF106406 | |
| Reactome | [www.reactome.org/content/detail/R-HSA-3214858 R-HSA-3214858] | |
| SIGNOR | Q68CP9 | |
| ChiTaRS | ARID2 | |
| GeneWiki | ARID2 | |
| GenomeRNAi | 196528 | |
| PMAP-CutDB | Q68CP9 | |
| PRO | PR:Q68CP9 | |
| Proteomes | UP000005640 | |
| Bgee | ENSG00000189079 | |
| ExpressionAtlas | Q68CP9 | |
| Genevisible | Q68CP9 | |
| GO | GO:0090544 GO:0005654 GO:0005886 GO:0003677 GO:0046872 GO:0060038 GO:0060982 GO:0016569 GO:0048568 GO:0003007 GO:0042592 GO:0030336 GO:0008285 GO:0006337 GO:0006355 GO:0006351 | |
| Gene3D | 1.10.10.10 1.10.150.60 | |
| InterPro | IPR001606 IPR016024 IPR003150 IPR011991 IPR007087 | |
| Pfam | PF01388 PF02257 | |
| SMART | SM00501 | |
| SUPFAM | SSF46774 SSF46785 SSF48371 | |
| PROSITE | PS51011 PS51526 PS00028 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
enables |
GO:0000981 |
DNA-binding transcription factor activity, RNA polymerase II-specific |
ECO:0005556 |
multiple sequence alignment evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0008285 |
negative regulation of cell population proliferation |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0030336 |
negative regulation of cell migration |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003677 |
DNA binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006337 |
nucleosome disassembly |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005886 |
plasma membrane |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
| GO:1905168 |
positive regulation of double-strand break repair via homologous recombination |
ECO:0000315 |
P |
Baf200 (Arid2) PBAF-defining subunit/AT-rich interactive domain-containing protein 2. Homo sapiens. FIGURE 4. Baf200 and Baf180 expression is important for homologous recombination. |
complete | |||||
|
part_of |
GO:0005654 |
nucleoplasm |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006357 |
regulation of transcription by RNA polymerase II |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0000981 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0072358 |
cardiovascular system development |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:E9Q7E2 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0060982 |
coronary artery morphogenesis |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:E9Q7E2 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0060038 |
cardiac muscle cell proliferation |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:E9Q7E2 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0048568 |
embryonic organ development |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:E9Q7E2 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0042592 |
homeostatic process |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:E9Q7E2 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0003007 |
heart morphogenesis |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:E9Q7E2 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0003676 |
nucleic acid binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003677 |
DNA binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006355 |
regulation of transcription, DNA-templated |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0046872 |
metal ion binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006325 |
chromatin organization |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003677 |
DNA binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Yu, P et al. (2015) miR-208-3p promotes hepatocellular carcinoma cell proliferation and invasion through regulating ARID2 expression. Exp. Cell Res. 336 232-41 PubMed GONUTS page
- ↑ Patsialou, A et al. (2005) DNA-binding properties of ARID family proteins. Nucleic Acids Res. 33 66-80 PubMed GONUTS page
- ↑ Wang, W et al. (1996) Purification and biochemical heterogeneity of the mammalian SWI-SNF complex. EMBO J. 15 5370-82 PubMed GONUTS page
- ↑ de Castro, RO et al. (2017) The Chromatin-remodeling Subunit Baf200 Promotes Homology-directed DNA Repair and Regulates Distinct Chromatin-remodeling Complexes. J. Biol. Chem. PubMed GONUTS page
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