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HUMAN:AR6P1
Contents
| Species (Taxon ID) | Homo sapiens (Human). (9606) | |
| Gene Name(s) | ARL6IP1 (synonyms: ARL6IP, KIAA0069) | |
| Protein Name(s) | ADP-ribosylation factor-like protein 6-interacting protein 1
ARL-6-interacting protein 1 Aip-1 | |
| External Links | ||
| UniProt | Q15041 | |
| EMBL | D31885 AK300869 AK301636 AC138811 BC010281 | |
| CCDS | CCDS10572.1 | |
| RefSeq | NP_001300787.1 NP_055976.1 | |
| UniGene | Hs.634882 | |
| ProteinModelPortal | Q15041 | |
| BioGrid | 116812 | |
| IntAct | Q15041 | |
| MINT | MINT-1378119 | |
| STRING | 9606.ENSP00000306788 | |
| iPTMnet | Q15041 | |
| PhosphoSite | Q15041 | |
| BioMuta | ARL6IP1 | |
| DMDM | 14424435 | |
| EPD | Q15041 | |
| MaxQB | Q15041 | |
| PaxDb | Q15041 | |
| PeptideAtlas | Q15041 | |
| PRIDE | Q15041 | |
| TopDownProteomics | Q15041 | |
| DNASU | 23204 | |
| Ensembl | ENST00000304414 ENST00000546206 | |
| GeneID | 23204 | |
| KEGG | hsa:23204 | |
| UCSC | uc002dfl.2 | |
| CTD | 23204 | |
| GeneCards | ARL6IP1 | |
| HGNC | HGNC:697 | |
| HPA | HPA045307 | |
| MalaCards | ARL6IP1 | |
| MIM | 607669 615685 | |
| neXtProt | NX_Q15041 | |
| Orphanet | 401780 | |
| PharmGKB | PA162376894 | |
| eggNOG | ENOG410IHBG ENOG410Z6SH | |
| GeneTree | ENSGT00390000005707 | |
| HOGENOM | HOG000034032 | |
| HOVERGEN | HBG050558 | |
| InParanoid | Q15041 | |
| OMA | HGIISKY | |
| OrthoDB | EOG7CZK70 | |
| PhylomeDB | Q15041 | |
| TreeFam | TF105477 | |
| GeneWiki | ARL6IP1 | |
| GenomeRNAi | 23204 | |
| NextBio | 35480048 | |
| PRO | PR:Q15041 | |
| Proteomes | UP000005640 | |
| Bgee | Q15041 | |
| CleanEx | HS_ARL6IP1 | |
| ExpressionAtlas | Q15041 | |
| Genevisible | Q15041 | |
| GO | GO:0005829 GO:0016021 GO:0016020 GO:0005784 GO:0006613 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
involved_in |
GO:0002038 |
positive regulation of L-glutamate import across plasma membrane |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0043154 |
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0043066 |
negative regulation of apoptotic process |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0030176 |
integral component of endoplasmic reticulum membrane |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:1990809 |
endoplasmic reticulum tubular network membrane organization |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0071787 |
endoplasmic reticulum tubular network formation |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005789 |
endoplasmic reticulum membrane |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016020 |
membrane |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:1858943 |
C |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006613 |
cotranslational protein targeting to membrane |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:1858943 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005784 |
Sec61 translocon complex |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:1858943 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0042802 |
identical protein binding |
ECO:0000353 |
physical interaction evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q9JKW0 |
C |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006613 |
cotranslational protein targeting to membrane |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q9JKW0 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005829 |
cytosol |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q9JKW0 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005784 |
Sec61 translocon complex |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q9JKW0 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005783 |
endoplasmic reticulum |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q9JKW0 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q9JKW0 |
C |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0002038 |
positive regulation of L-glutamate import across plasma membrane |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q9JKW0 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006915 |
apoptotic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016020 |
membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005783 |
endoplasmic reticulum |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005789 |
endoplasmic reticulum membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
| GO:0005789 |
endoplasmic reticulum membrane |
ECO:0000314 |
C |
Figure 1(B) and 1(C) shows localization of endogenous Arl6IP1 at the ER. |
complete | |||||
|
part_of |
GO:0012505 |
endomembrane system |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
| GO:1903371 |
regulation of endoplasmic reticulum tubular network organization |
ECO:0000315 |
P |
Figure 4(A) shows stabilization of the tubular structures of the ER in the absence of microtubules by overexpression of Arl6IP1. |
complete | |||||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 Lui, HM et al. (2003) ARMER, apoptotic regulator in the membrane of the endoplasmic reticulum, a novel inhibitor of apoptosis. Mol. Cancer Res. 1 508-18 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 2.4 Yamamoto, Y et al. (2014) Arl6IP1 has the ability to shape the mammalian ER membrane in a reticulon-like fashion. Biochem. J. 458 69-79 PubMed GONUTS page
- ↑ Ghosh, D et al. (2010) Defining the membrane proteome of NK cells. J Mass Spectrom 45 1-25 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
- ↑ Rolland, T et al. (2014) A proteome-scale map of the human interactome network. Cell 159 1212-26 PubMed GONUTS page
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