HUMAN:ABCG1

Species (Taxon ID)	Homo sapiens (Human). (9606)
Gene Name(s)	ABCG1 (synonyms: ABC8, WHT1)
Protein Name(s)	ATP-binding cassette sub-family G member 1 ATP-binding cassette transporter 8 White protein homolog
External Links
UniProt	P45844
EMBL	X91249 AB038161 AJ289137 AJ289138 AJ289139 AJ289140 AJ289141 AJ289142 AJ289143 AJ289144 AJ289145 AJ289146 AJ289147 AJ289148 AJ289149 AJ289150 AJ289151 AF323658 AF323644 AF323645 AF323646 AF323647 AF323648 AF323649 AF323650 AF323651 AF323652 AF323653 AF323654 AF323655 AF323656 AF323657 AF323664 AF323658 AF323640 AF323645 AF323646 AF323647 AF323648 AF323649 AF323650 AF323651 AF323652 AF323653 AF323654 AF323655 AF323656 AF323657 AF323660 AF323663 AF323658 AF323642 AF323645 AF323646 AF323647 AF323648 AF323649 AF323650 AF323651 AF323652 AF323653 AF323654 AF323655 AF323656 AF323657 AF323662 AF323658 AF323643 AF323645 AF323646 AF323647 AF323648 AF323649 AF323650 AF323651 AF323652 AF323653 AF323654 AF323655 AF323656 AF323657 AF323658 AF323645 AF323646 AF323647 AF323648 AF323649 AF323650 AF323651 AF323652 AF323653 AF323654 AF323655 AF323656 AF323657 AF323661 AY048757 AP001746 BC029158 U34919
CCDS	CCDS13681.1 CCDS13682.1 CCDS13683.1 CCDS42937.1 CCDS42938.1
RefSeq	NP_004906.3 NP_058198.2 NP_997057.1 NP_997510.1 NP_997511.1 NP_997512.1
UniGene	Hs.124649 Hs.418279
ProteinModelPortal	P45844
SMR	P45844
BioGrid	114980
IntAct	P45844
STRING	9606.ENSP00000354995
DrugBank	DB00171
TCDB	3.A.1.204.12
PhosphoSite	P45844
BioMuta	ABCG1
DMDM	17433715
MaxQB	P45844
PaxDb	P45844
PRIDE	P45844
DNASU	9619
Ensembl	ENST00000343687 ENST00000347800 ENST00000361802 ENST00000398449 ENST00000398457
GeneID	9619
KEGG	hsa:9619
UCSC	uc002zam.3 uc002zan.3 uc002zao.3 uc002zap.3 uc002zaq.3 uc002zar.3
CTD	9619
GeneCards	GC21P043619
HGNC	HGNC:73
HPA	HPA031470 HPA031471
MIM	603076
neXtProt	NX_P45844
PharmGKB	PA24408
eggNOG	COG1131
GeneTree	ENSGT00740000114855
HOVERGEN	HBG103052
InParanoid	P45844
KO	K05679
OMA	ASMEGCH
OrthoDB	EOG7KWSGT
PhylomeDB	P45844
TreeFam	TF105210
Reactome	REACT_111158 REACT_13621
ChiTaRS	ABCG1
GeneWiki	ABCG1
GenomeRNAi	9619
NextBio	36087
PRO	PR:P45844
Proteomes	UP000005640
Bgee	P45844
ExpressionAtlas	P45844
Genevisible	P45844
GO	GO:0005789 GO:0005768 GO:0009897 GO:0005794 GO:0000139 GO:0005887 GO:0043231 GO:0005739 GO:0005654 GO:0005886 GO:0055037 GO:0043531 GO:0005524 GO:0015485 GO:0017127 GO:0034437 GO:0005543 GO:0005548 GO:0046983 GO:0046982 GO:0042803 GO:0034041 GO:0019534 GO:0042987 GO:0033344 GO:0042632 GO:0008203 GO:0009720 GO:0034436 GO:0034375 GO:0032367 GO:0042157 GO:0034374 GO:0010887 GO:0010745 GO:0033700 GO:0055091 GO:0045542 GO:0010875 GO:0010872 GO:0006355 GO:0055099 GO:0033993 GO:0010033 GO:0043691 GO:0044281 GO:1901998 GO:0055085
Gene3D	3.40.50.300
InterPro	IPR003593 IPR013525 IPR003439 IPR017871 IPR020064 IPR027417 IPR005284
PANTHER	PTHR19241:SF177
Pfam	PF01061 PF00005
SMART	SM00382
SUPFAM	SSF52540
TIGRFAMs	TIGR00955
PROSITE	PS00211 PS50893

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Notes	Status
involved_in	GO:0055091	phospholipid homeostasis	PMID:16702602^[1]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	Seeded From UniProt	complete
part_of	GO:0055037	recycling endosome	PMID:16556852^[2]	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q64343	C	Seeded From UniProt	complete
enables	GO:0046982	protein heterodimerization activity	PMID:16870176^[3]	ECO:0000353	physical interaction evidence used in manual assertion	UniProtKB:Q9H172	F	Seeded From UniProt	complete
involved_in	GO:0045542	positive regulation of cholesterol biosynthetic process	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q64343	P	Seeded From UniProt	complete
involved_in	GO:0043691	reverse cholesterol transport	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q64343	P	Seeded From UniProt	complete
enables	GO:0043531	ADP binding	PMID:16702602^[1]	ECO:0000314	direct assay evidence used in manual assertion		F	Seeded From UniProt	complete
involved_in	GO:0042987	amyloid precursor protein catabolic process	PMID:17293612^[4]	ECO:0000314	direct assay evidence used in manual assertion		P	Seeded From UniProt	complete
enables	GO:0042803	protein homodimerization activity	PMID:16870176^[3]	ECO:0000314	direct assay evidence used in manual assertion		F	Seeded From UniProt	complete
involved_in	GO:0042632	cholesterol homeostasis	PMID:15994327^[5]	ECO:0000314	direct assay evidence used in manual assertion		P	Seeded From UniProt	complete
enables	GO:0034437	glycoprotein transmembrane transporter activity	PMID:17293612^[4]	ECO:0000314	direct assay evidence used in manual assertion		F	Seeded From UniProt	complete
involved_in	GO:0034436	glycoprotein transport	PMID:17293612^[4]	ECO:0000314	direct assay evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0034375	high-density lipoprotein particle remodeling	PMID:16556852^[2]	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q64343	P	Seeded From UniProt	complete
involved_in	GO:0034374	low-density lipoprotein particle remodeling	PMID:16556852^[2]	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q64343	P	Seeded From UniProt	complete
enables	GO:0034041	sterol-transporting ATPase activity	PMID:17408620^[6]	ECO:0000314	direct assay evidence used in manual assertion		F	Seeded From UniProt	complete
involved_in	GO:0033993	response to lipid	PMID:16556852^[2]	ECO:0000314	direct assay evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0033700	phospholipid efflux	PMID:16702602^[1]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0033344	cholesterol efflux	PMID:15994327^[5]	ECO:0000314	direct assay evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0032367	intracellular cholesterol transport	PMID:15994327^[5]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	Seeded From UniProt	complete
enables	GO:0019534	toxin transmembrane transporter activity	PMID:17408620^[6]	ECO:0000314	direct assay evidence used in manual assertion		F	Seeded From UniProt	complete
enables	GO:0017127	cholesterol transporter activity	PMID:15994327^[5]	ECO:0000314	direct assay evidence used in manual assertion		F	Seeded From UniProt	complete
enables	GO:0015485	cholesterol binding	PMID:15994327^[5]	ECO:0000305	curator inference used in manual assertion	GO:0017127	F	Seeded From UniProt	complete
involved_in	GO:0010872	regulation of cholesterol esterification	PMID:16556852^[2]	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q64343	P	Seeded From UniProt	complete
part_of	GO:0009897	external side of plasma membrane	PMID:16556852^[2]	ECO:0000314	direct assay evidence used in manual assertion		C	Seeded From UniProt	complete
involved_in	GO:0008203	cholesterol metabolic process	PMID:15994327^[5]	ECO:0000314	direct assay evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0006355	regulation of transcription, DNA-templated	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q64343	P	Seeded From UniProt	complete
part_of	GO:0005768	endosome	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q64343	C	Seeded From UniProt	complete
enables	GO:0005548	phospholipid transporter activity	PMID:16702602^[1]	ECO:0000314	direct assay evidence used in manual assertion		F	Seeded From UniProt	complete
enables	GO:0005543	phospholipid binding	PMID:16702602^[1]	ECO:0000305	curator inference used in manual assertion	GO:0005548	F	Seeded From UniProt	complete
enables	GO:0005524	ATP binding	PMID:16702602^[1]	ECO:0000314	direct assay evidence used in manual assertion		F	Seeded From UniProt	complete
enables	GO:0046983	protein dimerization activity	PMID:11500512^[7]	ECO:0000303	author statement without traceable support used in manual assertion		F	Seeded From UniProt	complete
involved_in	GO:0010033	response to organic substance	PMID:11500512^[7]	ECO:0000314	direct assay evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0009720	detection of hormone stimulus	PMID:11500512^[7]	ECO:0000303	author statement without traceable support used in manual assertion		P	Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	PMID:16780588^[8]	ECO:0007005	high throughput direct assay evidence used in manual assertion		C	Seeded From UniProt	complete
part_of	GO:0005794	Golgi apparatus	PMID:16780588^[8]	ECO:0007005	high throughput direct assay evidence used in manual assertion		C	Seeded From UniProt	complete
part_of	GO:0005739	mitochondrion	PMID:22042635^[9]	ECO:0000314	direct assay evidence used in manual assertion		C	Seeded From UniProt	complete
involved_in	GO:0055085	transmembrane transport	PMID:21873635^[10]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0003996 FB:FBgn0020762 PANTHER:PTN000443108 TAIR:locus:2084081	P	Seeded From UniProt	complete
involved_in	GO:0042632	cholesterol homeostasis	PMID:21873635^[10]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN002710416 UniProtKB:P45844	P	Seeded From UniProt	complete
enables	GO:0042626	ATPase activity, coupled to transmembrane movement of substances	PMID:21873635^[10]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0020762 PANTHER:PTN000443108 TAIR:locus:2016089 UniProtKB:Q9H221 UniProtKB:Q9H222	F	Seeded From UniProt	complete
enables	GO:0034041	sterol-transporting ATPase activity	PMID:21873635^[10]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN002710416 UniProtKB:P45844	F	Seeded From UniProt	complete
involved_in	GO:0033344	cholesterol efflux	PMID:21873635^[10]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:107704 PANTHER:PTN001059392 UniProtKB:P45844	P	Seeded From UniProt	complete
involved_in	GO:0033344	cholesterol efflux	PMID:21873635^[10]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:107704 MGI:MGI:1890594 PANTHER:PTN001059392 UniProtKB:P45844	P	Seeded From UniProt	complete
enables	GO:0017127	cholesterol transporter activity	PMID:21873635^[10]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN002710416 UniProtKB:P45844	F	Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	PMID:21873635^[10]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000443108 PomBase:SPCC18B5.01c RGD:631345 SGD:S000002418 SGD:S000005537 SGD:S000005679 SGD:S000005855 SGD:S000005979 TAIR:locus:2009680 TAIR:locus:2016089 TAIR:locus:2019693 TAIR:locus:2028656 TAIR:locus:2030898 TAIR:locus:2037703 TAIR:locus:2039523 TAIR:locus:2039682 TAIR:locus:2044893 TAIR:locus:2046203 TAIR:locus:2049867 TAIR:locus:2084081 TAIR:locus:2090009 TAIR:locus:2100514 TAIR:locus:2124029 TAIR:locus:2144133 TAIR:locus:2196593 UniProtKB:A0A1D8PCM6 UniProtKB:A0A1D8PE84 UniProtKB:A0A1D8PQ95 UniProtKB:E9RBG1 UniProtKB:Q4X006 UniProtKB:Q8H8V7 UniProtKB:Q94A18 UniProtKB:Q9UNQ0	C	Seeded From UniProt	complete
enables	GO:0005548	phospholipid transporter activity	PMID:21873635^[10]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN002710416 UniProtKB:P45844	F	Seeded From UniProt	complete
involved_in	GO:1901998	toxin transport	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0019534	P	Seeded From UniProt	complete
involved_in	GO:0071403	cellular response to high density lipoprotein particle stimulus	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q64343 ensembl:ENSMUSP00000024829	P	Seeded From UniProt	complete
part_of	GO:0055037	recycling endosome	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q64343 ensembl:ENSMUSP00000024829	C	Seeded From UniProt	complete
involved_in	GO:0045542	positive regulation of cholesterol biosynthetic process	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q64343 ensembl:ENSMUSP00000024829	P	Seeded From UniProt	complete
involved_in	GO:0043691	reverse cholesterol transport	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q64343 ensembl:ENSMUSP00000024829	P	Seeded From UniProt	complete
involved_in	GO:0034375	high-density lipoprotein particle remodeling	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q64343 ensembl:ENSMUSP00000024829	P	Seeded From UniProt	complete
involved_in	GO:0034374	low-density lipoprotein particle remodeling	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q64343 ensembl:ENSMUSP00000024829	P	Seeded From UniProt	complete
involved_in	GO:0033344	cholesterol efflux	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q64343 ensembl:ENSMUSP00000024829	P	Seeded From UniProt	complete
involved_in	GO:0030301	cholesterol transport	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q64343 ensembl:ENSMUSP00000024829	P	Seeded From UniProt	complete
involved_in	GO:0010888	negative regulation of lipid storage	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q64343 ensembl:ENSMUSP00000024829	P	Seeded From UniProt	complete
involved_in	GO:0010875	positive regulation of cholesterol efflux	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q64343 ensembl:ENSMUSP00000024829	P	Seeded From UniProt	complete
involved_in	GO:0010872	regulation of cholesterol esterification	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q64343 ensembl:ENSMUSP00000024829	P	Seeded From UniProt	complete
part_of	GO:0009897	external side of plasma membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q64343 ensembl:ENSMUSP00000024829	C	Seeded From UniProt	complete
involved_in	GO:0006355	regulation of transcription, DNA-templated	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q64343 ensembl:ENSMUSP00000024829	P	Seeded From UniProt	complete
part_of	GO:0005768	endosome	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q64343 ensembl:ENSMUSP00000024829	C	Seeded From UniProt	complete
enables	GO:0005524	ATP binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR003439 InterPro:IPR017871 InterPro:IPR020064	F	Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR013525	C	Seeded From UniProt	complete
part_of	GO:0016021	integral component of membrane	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR005284 InterPro:IPR020064	C	Seeded From UniProt	complete
enables	GO:0016887	ATPase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR003439 InterPro:IPR017871	F	Seeded From UniProt	complete
enables	GO:0017127	cholesterol transporter activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR020064	F	Seeded From UniProt	complete
involved_in	GO:0032367	intracellular cholesterol transport	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR020064	P	Seeded From UniProt	complete
involved_in	GO:0055085	transmembrane transport	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR005284	P	Seeded From UniProt	complete
involved_in	GO:0010887	negative regulation of cholesterol storage	PMID:18490524^[11]	ECO:0000304	author statement supported by traceable reference used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0010745	negative regulation of macrophage derived foam cell differentiation	PMID:18490524^[11]	ECO:0000304	author statement supported by traceable reference used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0055085	transmembrane transport	Reactome:R-HSA-382556	ECO:0000304	author statement supported by traceable reference used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0034375	high-density lipoprotein particle remodeling	Reactome:R-HSA-8964058	ECO:0000304	author statement supported by traceable reference used in manual assertion		P	Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	Reactome:R-HSA-266082	ECO:0000304	author statement supported by traceable reference used in manual assertion		C	Seeded From UniProt	complete
part_of	GO:0005783	endoplasmic reticulum	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0256	C	Seeded From UniProt	complete
enables	GO:0005524	ATP binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0067	F	Seeded From UniProt	complete
part_of	GO:0005794	Golgi apparatus	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0333	C	Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0472	C	Seeded From UniProt	complete
enables	GO:0000166	nucleotide binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0547	F	Seeded From UniProt	complete
involved_in	GO:0006869	lipid transport	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0445	P	Seeded From UniProt	complete
part_of	GO:0016021	integral component of membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0812	C	Seeded From UniProt	complete
part_of	GO:0005789	endoplasmic reticulum membrane	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0097	C	Seeded From UniProt	complete
part_of	GO:0000139	Golgi membrane	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0134	C	Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 ^1.2 ^1.3 ^1.4 ^1.5 Kobayashi, A et al. (2006) Efflux of sphingomyelin, cholesterol, and phosphatidylcholine by ABCG1. J. Lipid Res. 47 1791-802 PubMed GONUTS page
↑ ^2.0 ^2.1 ^2.2 ^2.3 ^2.4 ^2.5 Wang, N et al. (2006) LXR-induced redistribution of ABCG1 to plasma membrane in macrophages enhances cholesterol mass efflux to HDL. Arterioscler. Thromb. Vasc. Biol. 26 1310-6 PubMed GONUTS page
↑ ^3.0 ^3.1 Engel, T et al. (2006) Expression and functional characterization of ABCG1 splice variant ABCG1(666). FEBS Lett. 580 4551-9 PubMed GONUTS page
↑ ^4.0 ^4.1 ^4.2 Tansley, GH et al. (2007) The cholesterol transporter ABCG1 modulates the subcellular distribution and proteolytic processing of beta-amyloid precursor protein. J. Lipid Res. 48 1022-34 PubMed GONUTS page
↑ ^5.0 ^5.1 ^5.2 ^5.3 ^5.4 ^5.5 Vaughan, AM & Oram, JF (2005) ABCG1 redistributes cell cholesterol to domains removable by high density lipoprotein but not by lipid-depleted apolipoproteins. J. Biol. Chem. 280 30150-7 PubMed GONUTS page
↑ ^6.0 ^6.1 Engel, T et al. (2007) Expression of ATP binding cassette-transporter ABCG1 prevents cell death by transporting cytotoxic 7beta-hydroxycholesterol. FEBS Lett. 581 1673-80 PubMed GONUTS page
↑ ^7.0 ^7.1 ^7.2 Kennedy, MA et al. (2001) Characterization of the human ABCG1 gene: liver X receptor activates an internal promoter that produces a novel transcript encoding an alternative form of the protein. J. Biol. Chem. 276 39438-47 PubMed GONUTS page
↑ ^8.0 ^8.1 Hu, YH et al. (2006) Cell array-based intracellular localization screening reveals novel functional features of human chromosome 21 proteins. BMC Genomics 7 155 PubMed GONUTS page
↑ Uhlén, M et al. (2012) Antibody-based protein profiling of the human chromosome 21. Mol. Cell Proteomics 11 M111.013458 PubMed GONUTS page
↑ ^10.0 ^10.1 ^10.2 ^10.3 ^10.4 ^10.5 ^10.6 ^10.7 ^10.8 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
↑ ^11.0 ^11.1 Mauldin, JP et al. (2008) Reduced expression of ATP-binding cassette transporter G1 increases cholesterol accumulation in macrophages of patients with type 2 diabetes mellitus. Circulation 117 2785-92 PubMed GONUTS page

[PMID:16702602-1] 1.0 ^1.1 ^1.2 ^1.3 ^1.4 ^1.5 Kobayashi, A et al. (2006) Efflux of sphingomyelin, cholesterol, and phosphatidylcholine by ABCG1. J. Lipid Res. 47 1791-802 PubMed GONUTS page

[PMID:16556852-2] 2.0 ^2.1 ^2.2 ^2.3 ^2.4 ^2.5 Wang, N et al. (2006) LXR-induced redistribution of ABCG1 to plasma membrane in macrophages enhances cholesterol mass efflux to HDL. Arterioscler. Thromb. Vasc. Biol. 26 1310-6 PubMed GONUTS page

[PMID:16870176-3] 3.0 ^3.1 Engel, T et al. (2006) Expression and functional characterization of ABCG1 splice variant ABCG1(666). FEBS Lett. 580 4551-9 PubMed GONUTS page

[PMID:17293612-4] 4.0 ^4.1 ^4.2 Tansley, GH et al. (2007) The cholesterol transporter ABCG1 modulates the subcellular distribution and proteolytic processing of beta-amyloid precursor protein. J. Lipid Res. 48 1022-34 PubMed GONUTS page

[PMID:15994327-5] 5.0 ^5.1 ^5.2 ^5.3 ^5.4 ^5.5 Vaughan, AM & Oram, JF (2005) ABCG1 redistributes cell cholesterol to domains removable by high density lipoprotein but not by lipid-depleted apolipoproteins. J. Biol. Chem. 280 30150-7 PubMed GONUTS page

[PMID:17408620-6] 6.0 ^6.1 Engel, T et al. (2007) Expression of ATP binding cassette-transporter ABCG1 prevents cell death by transporting cytotoxic 7beta-hydroxycholesterol. FEBS Lett. 581 1673-80 PubMed GONUTS page

[PMID:11500512-7] 7.0 ^7.1 ^7.2 Kennedy, MA et al. (2001) Characterization of the human ABCG1 gene: liver X receptor activates an internal promoter that produces a novel transcript encoding an alternative form of the protein. J. Biol. Chem. 276 39438-47 PubMed GONUTS page

[PMID:16780588-8] 8.0 ^8.1 Hu, YH et al. (2006) Cell array-based intracellular localization screening reveals novel functional features of human chromosome 21 proteins. BMC Genomics 7 155 PubMed GONUTS page

[PMID:22042635-9] Uhlén, M et al. (2012) Antibody-based protein profiling of the human chromosome 21. Mol. Cell Proteomics 11 M111.013458 PubMed GONUTS page

[PMID:21873635-10] 10.0 ^10.1 ^10.2 ^10.3 ^10.4 ^10.5 ^10.6 ^10.7 ^10.8 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:18490524-11] 11.0 ^11.1 Mauldin, JP et al. (2008) Reduced expression of ATP-binding cassette transporter G1 increases cholesterol accumulation in macrophages of patients with type 2 diabetes mellitus. Circulation 117 2785-92 PubMed GONUTS page

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HUMAN:ABCG1

Contents

Annotations

Notes

References

a

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