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HORSE:CYC

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Species (Taxon ID) Equus caballus (Horse). (9796)
Gene Name(s) CYCS (synonyms: CYC)
Protein Name(s) Cytochrome c
External Links
UniProt P00004
PIR A00005
UniGene Eca.1571
PDB 1AKK
1CRC
1FI7
1FI9
1GIW
1HRC
1I5T
1LC1
1LC2
1M60
1OCD
1U75
1WEJ
2FRC
2GIW
2PCB
3NBS
3NBT
3O1Y
3O20
3WC8
3WUI
4NFG
PDBsum 1AKK
1CRC
1FI7
1FI9
1GIW
1HRC
1I5T
1LC1
1LC2
1M60
1OCD
1U75
1WEJ
2FRC
2GIW
2PCB
3NBS
3NBT
3O1Y
3O20
3WC8
3WUI
4NFG
DisProt DP00006
ProteinModelPortal P00004
SMR P00004
DIP DIP-36774N
IntAct P00004
STRING 9796.ENSECAP00000012031
MoonProt P00004
eggNOG COG3474
HOGENOM HOG000009762
HOVERGEN HBG003023
InParanoid P00004
SABIO-RK P00004
EvolutionaryTrace P00004
PMAP-CutDB P00004
Proteomes UP000002281
GO GO:0005829
GO:0005758
GO:0070469
GO:0045155
GO:0020037
GO:0005506
GO:0006309
GO:0055114
Gene3D 1.10.760.10
InterPro IPR009056
IPR002327
PANTHER PTHR11961
Pfam PF00034
PRINTS PR00604
SUPFAM SSF46626
PROSITE PS51007

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0018063

cytochrome c-heme linkage

PMID:4344990[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0070069

cytochrome complex

PMID:4344990[1]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0020037

heme binding

PMID:4344990[1]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:2001056

positive regulation of cysteine-type endopeptidase activity

PMID:11112785[2]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0045155

electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P99999

F

Seeded From UniProt

complete

part_of

GO:0005829

cytosol

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P99999

C

Seeded From UniProt

complete

involved_in

GO:0006123

mitochondrial electron transport, cytochrome c to oxygen

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000238899
RGD:2451
SGD:S000000765
SGD:S000003809

P

Seeded From UniProt

complete

involved_in

GO:0006122

mitochondrial electron transport, ubiquinol to cytochrome c

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000238899
SGD:S000000765
SGD:S000003809

P

Seeded From UniProt

complete

part_of

GO:0005758

mitochondrial intermembrane space

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000238899
SGD:S000000765
SGD:S000003809
UniProtKB:P99999

C

Seeded From UniProt

complete

enables

GO:0042802

identical protein binding

PMID:20615990[4]

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:P00004

F

Seeded From UniProt

complete

enables

GO:0009055

electron transfer activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR002327
InterPro:IPR009056
InterPro:IPR036909

F

Seeded From UniProt

complete

enables

GO:0020037

heme binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR002327
InterPro:IPR009056
InterPro:IPR036909

F

Seeded From UniProt

complete

part_of

GO:0070469

respirasome

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0679

C

Seeded From UniProt

complete

involved_in

GO:0055114

oxidation-reduction process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0249

P

Seeded From UniProt

complete

involved_in

GO:0006915

apoptotic process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0053

P

Seeded From UniProt

complete

part_of

GO:0005739

mitochondrion

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0496

C

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

part_of

GO:0005758

mitochondrial intermembrane space

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0169

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 Stellwagen, E et al. (1972) The conformation of horse heart apocytochrome c. J. Biol. Chem. 247 8074-7 PubMed GONUTS page
  2. Yu, T et al. (2001) A mutational epitope for cytochrome C binding to the apoptosis protease activation factor-1. J. Biol. Chem. 276 13034-8 PubMed GONUTS page
  3. 3.0 3.1 3.2 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
  4. Hirota, S et al. (2010) Cytochrome c polymerization by successive domain swapping at the C-terminal helix. Proc. Natl. Acad. Sci. U.S.A. 107 12854-9 PubMed GONUTS page