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HHV11:LTP

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Species (Taxon ID) Human herpesvirus 1 (strain 17) (HHV-1) (Human herpes simplex virus1). (10299)
Gene Name(s) No Information Provided.
Protein Name(s) Large tegument protein deneddylase

Tegument protein VP1-2 Tegument protein VP1/2

External Links
UniProt P10220
EMBL X14112
DQ889502
FJ593289
PIR I30085
RefSeq YP_009137111.1
PDB 4TT0
4TT1
PDBsum 4TT0
4TT1
ProteinModelPortal P10220
BioGrid 971402
IntAct P10220
MINT MINT-6732711
MEROPS C76.001
GeneID 2703357
KEGG vg:2703357
Proteomes UP000009294
GO GO:0030430
GO:0042025
GO:0019033
GO:0019784
GO:0036459
GO:0039648
GO:0039693
InterPro IPR005210
IPR006928
Pfam PF04843
PF03586
PROSITE PS51521

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0019033

viral tegument

PMID:23408623[1]

ECO:0000314

C

Figure 6C

complete
CACAO 7003

part_of

GO:0019033

viral tegument

PMID:25609143[2]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0039708

nuclear capsid assembly

PMID:17715218[3]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0030430

host cell cytoplasm

PMID:17715218[3]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0019033

viral tegument

PMID:23408623[1]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0008234

cysteine-type peptidase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR034702

F

Seeded From UniProt

complete

enables

GO:0019784

NEDD8-specific protease activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR005210

F

Seeded From UniProt

complete

enables

GO:0036459

thiol-dependent ubiquitinyl hydrolase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR034702

F

Seeded From UniProt

complete

involved_in

GO:0039693

viral DNA genome replication

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR005210

P

Seeded From UniProt

complete

enables

GO:0036459

thiol-dependent ubiquitinyl hydrolase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:3.4.19.12

F

Seeded From UniProt

complete

part_of

GO:0042025

host cell nucleus

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000410382

C

Seeded From UniProt

complete

part_of

GO:0030430

host cell cytoplasm

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000410382

C

Seeded From UniProt

complete

enables

GO:0036459

thiol-dependent ubiquitinyl hydrolase activity

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000410382

F

Seeded From UniProt

complete

part_of

GO:0019033

viral tegument

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000410382

C

Seeded From UniProt

complete

involved_in

GO:0039648

modulation by virus of host protein ubiquitination

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000410382

P

Seeded From UniProt

complete

enables

GO:0008233

peptidase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0645

F

Seeded From UniProt

complete

part_of

GO:0042025

host cell nucleus

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-1048
UniProtKB-SubCell:SL-0414

C

Seeded From UniProt

complete

part_of

GO:0019033

viral tegument

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0920
UniProtKB-SubCell:SL-0273

C

Seeded From UniProt

complete

involved_in

GO:0016032

viral process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0945

P

Seeded From UniProt

complete

involved_in

GO:0039648

modulation by virus of host protein ubiquitination

GO_REF:0000037
GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-1127
UniProtKB-KW:KW-1130

P

Seeded From UniProt

complete

part_of

GO:0030430

host cell cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-1035
UniProtKB-SubCell:SL-0381

C

Seeded From UniProt

complete

enables

GO:0016787

hydrolase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0378

F

Seeded From UniProt

complete

part_of

GO:0019012

virion

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0946

C

Seeded From UniProt

complete

enables

GO:0008234

cysteine-type peptidase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0788

F

Seeded From UniProt

complete

involved_in

GO:0006508

proteolysis

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0645

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Henaff, D et al. (2013) Analysis of the early steps of herpes simplex virus 1 capsid tegumentation. J. Virol. 87 4895-906 PubMed GONUTS page
  2. Laine, RF et al. (2015) Structural analysis of herpes simplex virus by optical super-resolution imaging. Nat Commun 6 5980 PubMed GONUTS page
  3. 3.0 3.1 Coller, KE et al. (2007) The capsid and tegument of the alphaherpesviruses are linked by an interaction between the UL25 and VP1/2 proteins. J. Virol. 81 11790-7 PubMed GONUTS page