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HHV11:ICP4

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Species (Taxon ID) Human herpesvirus 1 (strain 17) (HHV-1) (Human herpes simplex virus1). (10299)
Gene Name(s) ICP4 (synonyms: IE175)
Protein Name(s) Major viral transcription factor

Alpha-4 protein Infected cell protein 4 Transcriptional activator IE175

External Links
UniProt P08392
EMBL X14112
X14112
X06461
L00036
L00036
PIR A23510
RefSeq NP_044662.1
NP_044676.1
ProteinModelPortal P08392
IntAct P08392
MINT MINT-6732561
PRIDE P08392
GeneID 2703391
2703392
Proteomes UP000009294
GO GO:0030430
GO:0042025
GO:0019033
GO:0003677
GO:0045893
GO:0034340
GO:0006351
InterPro IPR005205
IPR005206
Pfam PF03585
PF03584

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0019033

viral tegument

PMID:23408623[1]

ECO:0000314

C

Figure 6C

complete
CACAO 7001

involved_in

GO:0039695

DNA-templated viral transcription

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P09310

P

Seeded From UniProt

complete

part_of

GO:0019033

viral tegument

PMID:23408623[1]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0034340

response to type I interferon

PMID:16873258[2]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0042025

host cell nucleus

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR005205
InterPro:IPR005206

C

Seeded From UniProt

complete

involved_in

GO:0045893

positive regulation of transcription, DNA-templated

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR005205
InterPro:IPR005206

P

Seeded From UniProt

complete

part_of

GO:0019033

viral tegument

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0920
UniProtKB-SubCell:SL-0273

C

Seeded From UniProt

complete

part_of

GO:0042025

host cell nucleus

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-1048
UniProtKB-SubCell:SL-0414

C

Seeded From UniProt

complete

part_of

GO:0030430

host cell cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-1035
UniProtKB-SubCell:SL-0381

C

Seeded From UniProt

complete

part_of

GO:0019012

virion

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0946

C

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0238

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Henaff, D et al. (2013) Analysis of the early steps of herpes simplex virus 1 capsid tegumentation. J. Virol. 87 4895-906 PubMed GONUTS page
  2. Negorev, DG et al. (2006) Differential role of Sp100 isoforms in interferon-mediated repression of herpes simplex virus type 1 immediate-early protein expression. J. Virol. 80 8019-29 PubMed GONUTS page