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HELPY:MUTS2
Contents
| Species (Taxon ID) | Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacterpylori). (85962) | |
| Gene Name(s) | mutS2 (ECO:0000255 with HAMAP-Rule:MF_00092) (synonyms: mutSB) | |
| Protein Name(s) | Endonuclease MutS2 (ECO:0000255 with HAMAP-Rule:MF_00092) | |
| External Links | ||
| UniProt | O25338 | |
| EMBL | AE000511 | |
| PIR | E64597 | |
| RefSeq | NP_207415.1 WP_010875507.1 | |
| ProteinModelPortal | O25338 | |
| DIP | DIP-3208N | |
| IntAct | O25338 | |
| MINT | MINT-162121 | |
| STRING | 85962.HP0621 | |
| PRIDE | O25338 | |
| EnsemblBacteria | AAD07685 | |
| GeneID | 900258 | |
| KEGG | hpy:HP0621 | |
| PATRIC | 20592525 | |
| eggNOG | COG1193 | |
| KO | K07456 | |
| OMA | NAGGKTM | |
| OrthoDB | EOG6P5ZC4 | |
| BioCyc | HPY:HP0621-MONOMER | |
| Proteomes | UP000000429 | |
| GO | GO:0005524 GO:0016887 GO:0004519 GO:0030983 GO:0006298 GO:0045910 | |
| Gene3D | 3.40.50.300 | |
| HAMAP | MF_00092 | |
| InterPro | IPR000432 IPR007696 IPR005747 IPR027417 IPR002625 | |
| PANTHER | PTHR11361:SF14 | |
| Pfam | PF00488 PF01713 | |
| PIRSF | PIRSF005814 | |
| SMART | SM00534 SM00533 SM00463 | |
| SUPFAM | SSF48334 SSF52540 | |
| TIGRFAMs | TIGR01069 | |
| PROSITE | PS50828 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0045910 |
negative regulation of DNA recombination |
ECO:0000315 |
P |
Figure 4 shows that when mutS2 is not expressed, the frequency of recombination is very high. However, when mutS2 is expressed, intergenomic recombination is suppressed. |
complete | |||||
|
involved_in |
GO:0045910 |
negative regulation of DNA recombination |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0032300 |
mismatch repair complex |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG10625 |
C |
Seeded From UniProt |
complete | ||
|
contributes_to |
GO:0032143 |
single thymine insertion binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN002260779 |
F |
Seeded From UniProt |
complete | ||
|
contributes_to |
GO:0032137 |
guanine/thymine mispair binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:101816 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0008094 |
DNA-dependent ATPase activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN002260779 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0005524 |
ATP binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG10625 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0005524 |
ATP binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG10625 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0003684 |
damaged DNA binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:101816 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0090305 |
nucleic acid phosphodiester bond hydrolysis |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0004519 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0090305 |
nucleic acid phosphodiester bond hydrolysis |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0004519 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0090305 |
nucleic acid phosphodiester bond hydrolysis |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0004519 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0090305 |
nucleic acid phosphodiester bond hydrolysis |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0004518 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0004519 |
endonuclease activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005524 |
ATP binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006298 |
mismatch repair |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016887 |
ATPase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0030983 |
mismatched DNA binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0045910 |
negative regulation of DNA recombination |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003677 |
DNA binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000076352 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0004519 |
endonuclease activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000076352 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0005524 |
ATP binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000076352 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0004519 |
endonuclease activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004518 |
nuclease activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0000166 |
nucleotide binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003677 |
DNA binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016787 |
hydrolase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005524 |
ATP binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Kang, J et al. (2005) Structural and functional divergence of MutS2 from bacterial MutS1 and eukaryotic MSH4-MSH5 homologs. J. Bacteriol. 187 3528-37 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 2.4 2.5 2.6 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
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