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HAEDU:HGBA

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Species (Taxon ID) Haemophilus ducreyi (strain 35000HP / ATCC 700724). (233412)
Gene Name(s) hgbA (ECO:0000303 with PMID:7890379[1]) (synonyms: hupA (ECO:0000303 with PMID:8613384[2]))
Protein Name(s) Hemoglobin and hemoglobin-haptoglobin-binding protein (ECO:0000305)
External Links
UniProt Q47952
EMBL U17281
U34048
AE017143
RefSeq NP_874343.1
WP_010945753.1
ProteinModelPortal Q47952
STRING 233412.HD2025
EnsemblBacteria AAP96732
GeneID 1491851
KEGG hdu:HD2025
PATRIC 20180171
eggNOG COG1629
KO K16087
OMA GWIFEDS
OrthoDB EOG6HB9KP
BioCyc HDUC233412:GH5F-1827-MONOMER
Proteomes UP000001022
GO GO:0009279
GO:0016021
GO:0004872
GO:0005215
GO:0009405
Gene3D 2.170.130.10
2.40.170.20
InterPro IPR012910
IPR000531
IPR010949
Pfam PF07715
PF00593
TIGRFAMs TIGR01786

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0030492

hemoglobin binding

PMID:7890379[1]

ECO:0000314

F

Fig 1 shows SDS-page gel of HgbA from solubilized outer membranes of H. ducreyi strain 35000 affinity purified on human hemoglobin.

complete
CACAO 5146

part_of

GO:0019867

outer membrane

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR010949

C

Seeded From UniProt

complete

enables

GO:0022857

transmembrane transporter activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR010949

F

Seeded From UniProt

complete

involved_in

GO:0055085

transmembrane transport

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR010949

P

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

part_of

GO:0009279

cell outer membrane

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0998
UniProtKB-SubCell:SL-0040

C

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0812

C

Seeded From UniProt

complete

involved_in

GO:0009405

pathogenesis

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0843

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Elkins, C (1995) Identification and purification of a conserved heme-regulated hemoglobin-binding outer membrane protein from Haemophilus ducreyi. Infect. Immun. 63 1241-5 PubMed GONUTS page
  2. Stevens, MK et al. (1996) A hemoglobin-binding outer membrane protein is involved in virulence expression by Haemophilus ducreyi in an animal model. Infect. Immun. 64 1724-35 PubMed GONUTS page